Aiming Sun

发表

A target site for template-based design of measles virus entry inhibitors.

J. Snyder, A. Prussia, R. Plemper, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Dual Myxovirus Screen Identifies a Small-Molecule

M. Luo, R. Plemper, D. Steinhauer, 2013 .

Dual Myxovirus Screen Identifies a Small-Molecule Agonist of the Host Antiviral Response

M. Luo, R. Plemper, D. Steinhauer, 2013, Journal of Virology.

Cancer and virus leads by HTS, chemical design and SEA data mining.

J. Snyder, R. Dingledine, A. Prussia, 2009, Current topics in medicinal chemistry.

Potent non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex.

J. Snyder, A. Prussia, R. Plemper, 2008, Journal of medicinal chemistry.

Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex activity: Synthesis and in vitro evaluation.

J. Snyder, R. Plemper, Jeong-Joong Yoon, 2007, Bioorganic & medicinal chemistry letters.

Nonpeptide inhibitors of measles virus entry.

V. A. Palyulin, J. Snyder, A. Prussia, 2006, Journal of medicinal chemistry.

Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits.

J. Snyder, H. Fu, Jaeki Min, 2012, Chemistry & biology.

Ebselen Congeners Inhibit NADPH-oxidase 2 (Nox2)Dependent Superoxide Generation by Interrupting the Binding of Regulatory Subunits

J. Snyder, H. Fu, Jaeki Min, 2011 .

Discovering Small‐Molecule Estrogen Receptor α/Coactivator Binding Inhibitors: High‐Throughput Screening, Ligand Development, and Models for Enhanced Potency

J. Snyder, J. Katzenellenbogen, H. Fu, 2011, ChemMedChem.

Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa

J. Snyder, W. Kisiel, H. Shim, 2008 .

Discovery of aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90): Synthesis, biology, and molecular modeling.

J. Snyder, R. Dingledine, P. Thepchatri, 2008, Bioorganic & medicinal chemistry.

Inhibition of Breast Cancer Bone Metastasis and Pancreatic and Colon Cancer by Synthetic Curcumin Analogs

J. Snyder, D. Brat, E. Sausville, 2018 .

Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties.

J. Snyder, A. Marcus, H. Shim, 2012, International immunopharmacology.

Sphingoid bases and de novo ceramide synthesis: enzymes involved, pharmacology and mechanisms of action.

A. Merrill, D. Liotta, M. C. Sullards, 2003, Pharmacological research.

High-throughput Assays for Superoxide and Hydrogen Peroxide

J. Lambeth, J. Joseph, B. Kalyanaraman, 2014, The Journal of Biological Chemistry.

Synthesis and Metabolic Studies of Host Directed Inhibitors for Anti Viral Therapy.

J. Snyder, A. Prussia, P. Thepchatri, 2013, ACS medicinal chemistry letters.

Host-directed Inhibitors of Myxoviruses: Synthesis and in vitro Biochemical Evaluation.

J. Ndungu, J. Snyder, P. Thepchatri, 2011, ACS medicinal chemistry letters.

Synthesis of EF24-tripeptide chloromethyl ketone: a novel curcumin-related anticancer drug delivery system.

J. Snyder, D. Liotta, M. Shoji, 2006, Journal of medicinal chemistry.

Synthesis of EF24-tripeptide chloromethyl ketone: a novel curcumin-related anticancer drug delivery system.

J. Snyder, D. Liotta, M. Shoji, 2006, Journal of medicinal chemistry.

Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa.

J. Snyder, W. Kisiel, H. Shim, 2008, Journal of drug targeting.

Synthesis and SAR study of N-(4-hydroxy-3-(2-hydroxynaphthalene-1-yl)phenyl)-arylsulfonamides: heat shock protein 90 (Hsp90) inhibitors with submicromolar activity in an in vitro assay.

J. Snyder, P. Thepchatri, H. Fu, 2008, Bioorganic & medicinal chemistry letters.

Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody

J. Ndungu, J. Snyder, D. Brat, 2015, Journal of drug targeting.

3-Fluoropiperidines and N-methyl-3-fluoropiperidinium salts: the persistence of axial fluorine.

J. Snyder, D. Lankin, K. Hardcastle, 2005, Chemistry.

Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism.

J. Snyder, D. Liotta, Haipeng Hu, 2009, Bioorganic & medicinal chemistry letters.

Thioxo-dihydroquinazolin-one Compounds as Novel Inhibitors of Myeloperoxidase.

J. Lambeth, B. Diebold, Aiming Sun, 2015, ACS medicinal chemistry letters.

Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase: synthesis, structure-activity relationships, and pharmacokinetics.

J. Ndungu, J. Snyder, R. Plemper, 2012, Journal of medicinal chemistry.

Monocarbonyl analogs of curcumin inhibit growth of antibiotic sensitive and resistant strains of Mycobacterium tuberculosis.

J. Snyder, D. Kalman, D. Liotta, 2015, European journal of medicinal chemistry.

Antiviral Atropisomers: Conformational Energy Surfaces by NMR for Host-Directed Myxovirus Blockers

Gordon Wells, James P. Snyder, Aiming Sun, 2014, J. Chem. Inf. Model..

Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases.

Aiming Sun, Yoichi Shinkai, James P Snyder, 2010, Journal of molecular biology.

Autophagy and Apoptosis in Hepatocellular Carcinoma Induced by EF25-(GSH)2: A Novel Curcumin Analog

J. Snyder, Dahai Liu, H. Fu, 2014, PloS one.

Anticancer effects of monocarbonyl analogs of curcumin: oxidative stress, nuclear translocation and modulation of AP-1 and NF-κB

J. Snyder, D. Liotta, B. El-Rayes, 2015 .

EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism

Dean P. Jones, J. Snyder, Jiyang Cai, 2005, Anti-cancer drugs.

Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors

Chao Yang, J. Snyder, S. Hiddingh, 2009, Molecular Cancer.

Design of a Small-Molecule Entry Inhibitor with Activity against Primary Measles Virus Strains

J. Snyder, A. Prussia, R. Plemper, 2005, Antimicrobial Agents and Chemotherapy.

Asymmetric synthesis of host-directed inhibitors of myxoviruses

J. Ndungu, J. Snyder, P. Thepchatri, 2013, Beilstein journal of organic chemistry.

Inhibition of IκB Kinase-Nuclear Factor-κB Signaling Pathway by 3,5-Bis(2-flurobenzylidene)piperidin-4-one (EF24), a Novel Monoketone Analog of Curcumin

J. Snyder, F. Khuri, Shi-Yong Sun, 2008, Molecular Pharmacology.

Potent Host-Directed Small-Molecule Inhibitors of Myxovirus RNA-Dependent RNA-Polymerases

J. Ndungu, J. Snyder, R. Plemper, 2011, PloS one.

Target Analysis of the Experimental Measles Therapeutic AS-136A

J. Ndungu, J. Snyder, R. Plemper, 2009, Antimicrobial Agents and Chemotherapy.

Nonnucleoside Inhibitor of Measles Virus RNA-Dependent RNA Polymerase Complex Activity

J. Snyder, R. Plemper, H. Fu, 2007, Antimicrobial Agents and Chemotherapy.

Two Domains That Control Prefusion Stability and Transport Competence of the Measles Virus Fusion Protein

J. Snyder, A. Prussia, R. Plemper, 2006, Journal of Virology.

Tumor Angiogenesis Therapy Using Targeted Delivery of Paclitaxel to the Vasculature of Breast Cancer Metastases

Daniel J Brat, Aiming Sun, James P Snyder, 2014, Journal of drug delivery.

Novel curcumin analogue UBS109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis: involvement in Smad activation and NF-κB inhibition.

J. Snyder, M. Shoji, Aiming Sun, 2012, Integrative biology : quantitative biosciences from nano to macro.

High-Throughput Screening—Based Identification of Paramyxovirus Inhibitors

J. Snyder, R. Plemper, Yuhong Du, 2008, Journal of biomolecular screening.

Synthetic curcumin analog EF31 inhibits the growth of head and neck squamous cell carcinoma xenografts.

J. Snyder, G. Sica, F. Khuri, 2012, Integrative biology : quantitative biosciences from nano to macro.

An Orally Available, Small-Molecule Polymerase Inhibitor Shows Efficacy Against a Lethal Morbillivirus Infection in a Large Animal Model

R. Plemper, D. Liotta, V. von Messling, 2014, Science Translational Medicine.

Targeted delivery of paclitaxel to tumor cells: synthesis and in vitro evaluation.

J. Ndungu, J. Snyder, Xu Wang, 2010, Journal of medicinal chemistry.

Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor

R. Dingledine, P. Thepchatri, Yuhong Du, 2010, Proceedings of the National Academy of Sciences.

Enhancement of interferon gamma stability as an anticancer therapeutic protein against hepatocellular carcinoma upon interaction with calycosin.

Suliman Khan, K. Akhtari, Qian Bai, 2021, International journal of biological macromolecules.

Krumm Against a Lethal Morbillivirus Infection in a Large Animal Model An Orally Available , Small-Molecule Polymerase Inhibitor Shows Efficacy

R. Plemper, D. Liotta, M. Natchus, 2014 .

High-Throughput Screening—Based Identification of Paramyxovirus Inhibitors

J. Snyder, Yuhong Du, Jeong-Joong Yoon, 2008, Journal of biomolecular screening.

Inhibition of I (cid:1) B Kinase-Nuclear Factor- (cid:1) B Signaling Pathway by 3,5-Bis(2-flurobenzylidene)piperidin-4-one (EF24), a Novel Monoketone Analog of Curcumin □ S

F. Khuri, A. Kasinski, Yuhong Du, 2008 .