K. Cox

发表

A Tetravalent Sub-unit Dengue Vaccine Formulated with Ionizable Cationic Lipid Nanoparticle induces Significant Immune Responses in Rodents and Non-Human Primates

Marian E. Gindy, D. Casimiro, A. Bett, 2016, Scientific Reports.

A novel lipid nanoparticle adjuvant significantly enhances B cell and T cell responses to sub-unit vaccine antigens.

Marian E. Gindy, K. Vora, D. Casimiro, 2016, Vaccine.

Human monoclonal antibodies isolated from a primary pneumococcal conjugate Vaccinee demonstrates the expansion of an antigen-driven Hypermutated memory B cell response

K. Vora, L. Guan, T. Verch, 2018, BMC Infectious Diseases.

A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein

H. Su, K. Vora, M. Eddins, 2019, Nature Communications.

Profiling of hMPV F-specific antibodies isolated from human memory B cells

H. Su, K. Vora, M. Eddins, 2022, Nature Communications.

Modified mRNA/lipid nanoparticle-based vaccines expressing respiratory syncytial virus F protein variants are immunogenic and protective in rodent models of RSV infection

Amy S. Espeseth, Marian E. Gindy, D. Hazuda, 2020, npj Vaccines.

Respiratory syncytial virus elicits enriched CD8+ T lymphocyte responses in lung compared with blood in African green monkeys

Amy S. Espeseth, A. Espeseth, K. Vora, 2017, PloS one.

Effector and Central Memory Poly-Functional CD4+ and CD8+ T Cells are Boosted upon ZOSTAVAX® Vaccination

K. Vora, D. Casimiro, K. Cox, 2015, Front. Immunol..

A phase I study to evaluate safety, pharmacokinetics, and pharmacodynamics of respiratory syncytial virus neutralizing monoclonal antibody MK‐1654 in healthy Japanese adults

M. Kodama, O. Tokumaru, K. Cox, 2022, Clinical and translational science.

A Novel LNP-Based Chlamydia Subunit Vaccine Formulation That Induces Th1 Responses without Upregulating IL-17 Provides Equivalent Protection in Mice as Formulations That Induced IL-17 and Th1 Cytokines

Amy S. Espeseth, A. Espeseth, K. Vora, 2019, World Journal of Vaccines.

A phase I randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, and immunogenicity of a live-attenuated quadrivalent dengue vaccine in flavivirus-naïve and flavivirus-experienced healthy adults

K. Russell, R. Rupp, B. Coller, 2022, Human vaccines & immunotherapeutics.

Functional Evaluation and Genetic Evolution of Human T-cell Responses after Vaccination with a Conditionally Replication-Defective Cytomegalovirus Vaccine.

I. Wang, K. Vora, T. Fu, 2020, The Journal of infectious diseases.

Vaccination with Ad5 Vectors Expands Ad5-Specific CD8+ T Cells without Altering Memory Phenotype or Functionality

M. Betts, H. Ertl, D. Carnathan, 2010, PloS one.

The differential short- and long-term effects of HIV-1 latency-reversing agents on T cell function

M. Hudgens, D. Margolis, N. Archin, 2016, Scientific Reports.

AIDS clinical trials group 5197: a placebo-controlled trial of immunization of HIV-1-infected persons with a replication-deficient adenovirus type 5 vaccine expressing the HIV-1 core protein.

R. Schooley, M. Lederman, D. Kuritzkes, 2010, The Journal of infectious diseases.

CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells

D. Hazuda, D. Richman, J. Martinez-Picado, 2018, Science Translational Medicine.

Baseline Ad5 serostatus does not predict Ad5-HIV vaccine-induced expansion of Ad-specific CD4+ T-cells

M. Betts, H. Ertl, D. Carnathan, 2009, Nature Medicine.

Characterization of potent RSV neutralizing antibodies isolated from human memory B cells and identification of diverse RSV/hMPV cross-neutralizing epitopes

H. Su, K. Vora, C. Callahan, 2019, mAbs.

Evaluation of cellular immune responses in subjects chronically infected with HIV type 1.

S. Kalams, D. Mehrotra, M. Mulligan, 2007, AIDS research and human retroviruses.

PD-1 Blockade in Rhesus Macaques: Impact on Chronic Infection and Prophylactic Vaccination

D. Hazuda, J. Shiver, A. Finnefrock, 2009, The Journal of Immunology.

DNA gag/Adenovirus Type 5 (Ad5) gag and Ad5 gag/Ad5 gag Vaccines Induce Distinct T-Cell Response Profiles

J. Shiver, D. Casimiro, K. Cox, 2008, Journal of Virology.

A comparison of standard immunogenicity assays for monitoring HIV type 1 gag-specific T cell responses in Ad5 HIV Type 1 gag vaccinated human subjects.

Devan V Mehrotra, Robin Mogg, D. Mehrotra, 2006, AIDS research and human retroviruses.

Vaccinationon Chronic Infection and Prophylactic PD-1 Blockade in Rhesus Macaques: Impact

D. Hazuda, J. Shiver, A. Finnefrock, 2008 .

Co-Administration of Lipid Nanoparticles and Sub-Unit Vaccine Antigens Is Required for Increase in Antigen-Specific Immune Responses in Mice

Marian E. Gindy, D. Casimiro, A. Bett, 2016, Vaccines.

Efficacy of Multivalent Adenovirus-Based Vaccine against Simian Immunodeficiency Virus Challenge

D. Watkins, D. O’Connor, J. Shiver, 2009, Journal of Virology.

A phase 1, randomized, placebo-controlled study to evaluate the safety and immunogenicity of an mRNA-based RSV prefusion F protein vaccine in healthy younger and older adults

Daniel S Spellman, Amy S. Espeseth, A. Espeseth, 2020, Human vaccines & immunotherapeutics.

Efficient generation of monoclonal antibodies from single rhesus macaque antibody secreting cells

Xue-jun Fan, J. Joyce, D. Casimiro, 2015, mAbs.

The effect of early versus delayed challenge after vaccination in controlling SHIV 89.6P infection.

Leslie L. Chavez, A. Perelson, M. Davenport, 2008, Virology.

Corrigendum: Baseline Ad5 serostatus does not predict Ad5 HIV vaccine–induced expansion of adenovirus-specific CD4+ T cells

M. Betts, H. Ertl, D. Carnathan, 2009, Nature Medicine.

A replication-defective human cytomegalovirus vaccine for prevention of congenital infection

Jingyuan Xu, Dai Wang, Amy S. Espeseth, 2016, Science Translational Medicine.

A Phase 1 Randomized, Double‐Blind, Placebo‐Controlled Trial to Assess the Safety, Tolerability, and Pharmacokinetics of a Respiratory Syncytial Virus Neutralizing Monoclonal Antibody MK‐1654 in Healthy Adults

R. Railkar, K. Vora, K. Cox, 2020, Clinical pharmacology in drug development.

Rapid isolation of dengue-neutralizing antibodies from single cell-sorted human antigen-specific memory B-cell cultures

K. Vora, B. Doranz, D. Casimiro, 2015, mAbs.

DNA gag/Adenovirus Type 5 (Ad5) gag and Ad5 gag/Ad5 gag Vaccines Induce Distinct T-Cell Response Profiles

J. Shiver, D. Casimiro, K. Cox, 2008, Journal of Virology.

Efficacy of Multivalent Adenovirus-Based Vaccine against Simian Immunodeficiency Virus Challenge

D. Watkins, D. O’Connor, J. Shiver, 2009, Journal of Virology.

Characterization of humoral and cell-mediated immunity induced by mRNA vaccines expressing influenza hemagglutinin stem and nucleoprotein in mice and nonhuman primates.

Amy S. Espeseth, Marian E. Gindy, Kapil Bahl, 2022, Vaccine.