V. Dutoit

发表

Exploiting the glioblastoma peptidome to discover novel tumour-associated antigens for immunotherapy.

Hans-Georg Rammensee, Steffen Walter, Christel Herold-Mende, 2012, Brain : a journal of neurology.

Phagocytic function of tumor-associated macrophages as a key determinant of tumor progression control: a review

P. Walker, V. Dutoit, Marc Lecoultre, 2020, Journal for ImmunoTherapy of Cancer.

An Experimentally Defined Hypoxia Gene Signature in Glioblastoma and Its Modulation by Metformin

P. Walker, S. Tankov, P. Dietrich, 2020, Biology.

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma*

S. H. van der Burg, J. Castle, H. Rammensee, 2019, Molecular & Cellular Proteomics.

Expansion and functional maturation of human tumor antigen-specific CD8+ T cells after vaccination with antigenic peptide.

D. Speiser, P. Romero, D. Valmori, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Circulating Tumor-reactive CD8(+) T cells in melanoma patients contain a CD45RA(+)CCR7(-) effector subset exerting ex vivo tumor-specific cytolytic activity.

D. Schadendorf, E. Thiel, P. Romero, 2002, Cancer research.

Antigenicity and immunogenicity of Melan‐A/MART‐1 derived peptides as targets for tumor reactive CTL in human melanoma

D. Speiser, P. Romero, N. Rufer, 2002, Immunological reviews.

T-cell immunotherapy for malignant glioma: toward a combined approach

P. Walker, P. Dietrich, V. Dutoit, 2010, Current opinion in oncology.

Limits of CD133 as a marker of glioma self‐renewing cells

I. Radovanovic, D. Marino, P. Dietrich, 2009, International journal of cancer.

First report of clinical responses to immunotherapy in 3 relapsing cases of chordoma after failure of standard therapies

B. Landis, M. Becker, P. Dietrich, 2017, Oncoimmunology.

Treatment of hepatitis C in HCV mono-infected and in HIV-HCV co-infected patients: an open-labelled comparison study.

J. Borovička, E. Bernasconi, F. Negro, 2010, Swiss medical weekly.

Immunotherapy for glioma: from illusion to realistic prospects?

P. Walker, P. Dietrich, V. Dutoit, 2014, American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.

Immunotherapy of Brain Tumors.

P. Walker, P. Dietrich, V. Dutoit, 2015, Progress in tumor research.

CD8 + T-Cell Response to NY-ESO-I: Relative Antigenicity and in Vitro Immunogenicity of Natural and Analogue Sequences 1

V. Dutoit, J. C, Danielle Li, 2007 .

CD8+ T-cell response to NY-ESO-1: relative antigenicity and in vitro immunogenicity of natural and analogue sequences.

D. Speiser, P. Romero, D. Valmori, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Metataxonomic and Metabolic Impact of Fecal Microbiota Transplantation From Patients With Pancreatic Cancer Into Germ-Free Mice: A Pilot Study

J. Schrenzel, V. Lazarevic, L. Genton, 2021, Frontiers in Cellular and Infection Microbiology.

Decreased Binding of Peptides-MHC Class I (pMHC) Multimeric Complexes to CD8 Affects Their Binding Avidity for the TCR But Does Not Significantly Impact on pMHC/TCR Dissociation Rate1

D. Valmori, C. Hesdorffer, M. Ayyoub, 2003, The Journal of Immunology.

Self-Antigen Specific for a Human Tumor-Associated Selection of the Preimmune Repertoire-Chain in the α Prevalent Role of TCR Cerottini

M. Bonneville, P. Romero, P. Coulie, 2003 .

TCR Dissociation Rate But Does Not Significantly Impact on Affects Their Binding Avidity for the TCR ( pMHC ) Multimeric Complexes to CD 8 Decreased Binding of Peptides-MHC Class

D. Valmori, C. Hesdorffer, M. Ayyoub, 2003 .

Dissecting TCR‐MHC/peptide complex interactions with A2/peptide multimers incorporating tumor antigen peptide variants: crucial role of interaction kinetics on functional outcomes

P. Romero, D. Valmori, J. Cerottini, 2002, European journal of immunology.

Vaccination with a Melan-A Peptide Selects an Oligoclonal T Cell Population with Increased Functional Avidity and Tumor Reactivity1

P. Romero, M. Pittet, P. Walker, 2002, The Journal of Immunology.

Functional Avidity of Tumor Antigen-Specific CTL Recognition Directly Correlates with the Stability of MHC/Peptide Multimer Binding to TCR1

D. Speiser, P. Romero, D. Valmori, 2002, The Journal of Immunology.

Reactivity Increased Functional Avidity and Tumor an Oligoclonal T Cell Population with Vaccination with a MelanA Peptide Selects

P. Romero, M. Pittet, P. Walker, 2002 .

Functional analysis of HLA-A*0201/Melan-A peptide multimer+ CD8+ T cells isolated from an HLA-A*0201- donor: exploring tumor antigen allorestricted recognition.

P. Romero, D. Valmori, J. Cerottini, 2002, Cancer immunity.

This information is current as to TCR Stability of MHC / Peptide Multimer Binding theCTL Recognition Directly Correlates with Functional Avidity of Tumor Antigen-Specific Romero and Danila

D. Speiser, P. Romero, D. Valmori, 2002 .

Heterogeneous T-cell response to MAGE-A10(254-262): high avidity-specific cytolytic T lymphocytes show superior antitumor activity.

D. Speiser, P. Romero, D. Valmori, 2001, Cancer research.

Antitumor Activity Avidity-specific Cytolytic T Lymphocytes Show Superior : High 262 − 254 Heterogeneous T-Cell Response to MAGE-A 10 Updated Version

D. Speiser, P. Romero, D. Valmori, 2001 .

Efficient Simultaneous Presentation of NY-ESO-1/LAGE-1 Primary and Nonprimary Open Reading Frame-Derived CTL Epitopes in Melanoma

D. Speiser, P. Romero, D. Valmori, 2000, The Journal of Immunology.

Naturally occurring human lymphocyte antigen-A2 restricted CD8+ T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients.

D. Speiser, U. Şahin, P. Romero, 2000, Cancer research.

T Cells in Melanoma + Melan-A-Specific CD8 Usage Reveals a Large Repertoire of -Chain b Tetramer-Guided Analysis of TCR

D. Speiser, P. Romero, D. Valmori, 2000 .

CTL Epitopes in Melanoma Nonprimary Open Reading Frame-Derived NY-ESO-1 / LAGE-1 Primary and Efficient Simultaneous Presentation of and Danila

D. Speiser, P. Romero, D. Valmori, 2000 .

Frequent cytolytic T-cell responses to peptide MAGE-A10(254-262) in melanoma.

P. Romero, D. Valmori, J. Cerottini, 2001, Cancer research.

P. Dietrich, V. Dutoit, E. Marinari, 2016, Annals of oncology : official journal of the European Society for Medical Oncology.

Tissue homing and persistence of defined antigen-specific CD8+ tumor-reactive T-cell clones in long-term melanoma survivors.

J. Schrenzel, D. Speiser, P. Romero, 2007, The Journal of investigative dermatology.

Study protocol of a phase II study to evaluate safety and efficacy of neo-adjuvant pembrolizumab and radiotherapy in localized rectal cancer

F. Ris, T. Koessler, M. Di Marco, 2021, BMC Cancer.

Advances in Brief Frequent Cytolytic T-Cell Responses to Peptide MAGE-A 10254 – 262 in Melanoma 1

P. Romero, D. Valmori, J. Cerottini, 2001 .

Everolimus as first-line therapy in nonrapidly progressive metastatic castration-resistant prostate cancer (mCRPC): A multicenter phase II trial (SAKK 08/08).

R. Winterhalder, P. Wild, M. Borner, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Simultaneous CD8+ T cell responses to multiple tumor antigen epitopes in a multipeptide melanoma vaccine.

Danila Valmori, Pedro Romero, Philippe Guillaume, 2003, Cancer immunity.

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma.

S. H. van der Burg, J. Castle, H. Rammensee, 2019, Molecular & cellular proteomics : MCP.

Immunotherapy of Malignant Tumors in the Brain: How Different from Other Sites?

P. Walker, P. Dietrich, V. Dutoit, 2016, Front. Oncol..

Polyfunctional HCV‐specific T‐cell responses are associated with effective control of HCV replication

J. Borovička, M. Battegay, E. Bernasconi, 2008, European journal of immunology.

Allogeneic CAR T Cells: An Alternative to Overcome Challenges of CAR T Cell Therapy in Glioblastoma

V. Dutoit, D. Migliorini, D. Martínez Bedoya, 2021, Frontiers in Immunology.

Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells

J. Sarkaria, K. Krause, P. Walker, 2021, Communications biology.

Cancer Vaccines

H. Arkenau, A. Patrikidou, V. Dutoit, 2019, Cancer Immunotherapy and Biological Cancer Treatments.

Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma.

Karl-Heinz Krause, Paul S Mischel, Kun-Liang Guan, 2017, Cancer cell.

Extrachromosomal driver mutations in glioblastoma and low grade glioma

S. Antonarakis, S. Nikolaev, F. Béna, 2014, Nature Communications.

Combinatorial peptide libraries as an alternative approach to the identification of ligands for tumor-reactive cytolytic T lymphocytes.

R A Houghten, R Simon, R. Simon, 2001, Cancer research.

Peptides as cancer vaccines.

P. Walker, P. Dietrich, V. Dutoit, 2019, Current opinion in pharmacology.

Current strategies for vaccination in glioblastoma.

P. Dietrich, V. Dutoit, D. Migliorini, 2019, Current opinion in oncology.

Antigenic expression and spontaneous immune responses support the use of a selected peptide set from the IMA950 glioblastoma vaccine for immunotherapy of grade II and III glioma

J. Costello, S. Momjian, P. Walker, 2017, Oncoimmunology.

Actively personalized vaccination trial for newly diagnosed glioblastoma

J. Castle, H. Rammensee, S. Stevanović, 2018, Nature.

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma.

S. H. van der Burg, J. Castle, H. Rammensee, 2018, Molecular & cellular proteomics : MCP.

Clonal Evolution of a High-Grade Pediatric Glioma With Distant Metastatic Spread

S. Nikolaev, K. Schaller, P. Tsantoulis, 2021, Neurology: Genetics.

Lentivirus-mediated Rna Interference of Dc-sign Expression Inhibits Human Immunodeficiency Virus Transmission from Dendritic Cells to T Cells in the Early Events of Human Immunodeficiency Virus Type 1 (hiv-1) Infection, Immature Dendritic Cells (dcs) Expressing the Dc-specific Intercellular Adhesion

M. Wiznerowicz, D. Trono, T. Geijtenbeek, 2022 .

Functional signatures of protective antiviral T‐cell immunity in human virus infections

G. Pantaleo, A. Harari, R. D. Du Pasquier, 2006, Immunological reviews.

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma*

S. H. van der Burg, J. Castle, H. Rammensee, 2018, Molecular & Cellular Proteomics.

Emerging Trends for Radio-Immunotherapy in Rectal Cancer

T. Koessler, V. Dutoit, C. Corrò, 2021, Cancers.

Inflammation and lymphocyte infiltration are associated with shorter survival in patients with high-grade glioma

P. Tsantoulis, D. Merkler, P. Dietrich, 2020, Oncoimmunology.

Phase 2 trial of single-agent everolimus in chemotherapy-naive patients with castration-resistant prostate cancer (SAKK 08/08).

Ruedi Aebersold, Christian Rothermundt, Peter J Wild, 2013, European urology.

Oncolytic Viruses as a Platform for the Treatment of Malignant Brain Tumors

V. Dutoit, D. Migliorini, Jana de Sostoa, 2020, International journal of molecular sciences.

ER–mitochondria contacts control surface glycan expression and sensitivity to killer lymphocytes in glioma stem‐like cells

N. Hulo, P. Walker, D. Martinvalet, 2017, The EMBO journal.

Human tissue engineering allows the identification of active miRNA regulators of glioblastoma aggressiveness.

L. Farinelli, T. Petty, O. Preynat-Seauve, 2016, Biomaterials.

Comprehensive metagenomic analysis of glioblastoma reveals absence of known virus despite antiviral-like type I interferon gene response

L. Farinelli, K. Krause, E. Zdobnov, 2014, International journal of cancer.

The relationship between brain tumor cell invasion of engineered neural tissues and in vivo features of glioblastoma.

K. Krause, T. Virolle, H. Chneiweiss, 2013, Biomaterials.

Tetramer-Guided Analysis of TCR β-Chain Usage Reveals a Large Repertoire of Melan-A-Specific CD8+ T Cells in Melanoma Patients1

D. Speiser, P. Romero, V. Cerundolo, 2000, The Journal of Immunology.

Promises and Challenges of Predictive Blood Biomarkers for Locally Advanced Rectal Cancer Treated with Neoadjuvant Chemoradiotherapy

T. Koessler, V. Dutoit, C. Corrò, 2023, Cells.

Multiepitope CD8(+) T cell response to a NY-ESO-1 peptide vaccine results in imprecise tumor targeting.

Danila Valmori, Philippe Guillaume, Susan Talbot, 2002, The Journal of clinical investigation.

Therapeutic cancer vaccines based on molecularly defined human tumor antigens.

D. Speiser, P. Romero, M. Pittet, 2002, Vaccine.

Impact of Radiochemotherapy on Immune Cell Subtypes in High-Grade Glioma Patients

K. Schaller, P. Dietrich, V. Dutoit, 2020, Frontiers in Oncology.

Differences in HCV‐specific T cell responses between chronic HCV infection and HIV/HCV co‐infection

G. Pantaleo, J. Gonvers, V. Dutoit, 2005, European journal of immunology.

Discrepancy between ELISPOT IFN-γ secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life

D. Speiser, P. Romero, D. Valmori, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Prevalent Role of TCR α-Chain in the Selection of the Preimmune Repertoire Specific for a Human Tumor-Associated Self-Antigen1

M. Bonneville, P. Romero, P. Coulie, 2003, The Journal of Immunology.

Positional Scanning-Synthetic Peptide Library-Based Analysis of Self- and Pathogen-Derived Peptide Cross-Reactivity with Tumor-Reactive Melan-A-Specific CTL1

Yingdong Zhao, Clemencia Pinilla, Danila Valmori, 2002, The Journal of Immunology.

Degeneracy of Antigen Recognition as the Molecular Basis for the High Frequency of Naive A2/Melan-A Peptide Multimer+ CD8+ T Cells in Humans

R. Houghten, C. Pinilla, P. Romero, 2002, The Journal of experimental medicine.

Toward synthetic combinatorial peptide libraries in positional scanning format (PS-SCL)-based identification of CD8+ Tumor-reactive T-Cell Ligands: a comparative analysis of PS-SCL recognition by a single tumor-reactive CD8+ cytolytic T-lymphocyte clone.

Yingdong Zhao, Clemencia Pinilla, Danila Valmori, 2002, Cancer research.

Melanoma patients respond to a cytotoxic T lymphocyte-defined self-peptide with diverse and nonoverlapping T-cell receptor repertoires.

P. Romero, P. Walker, D. Valmori, 2001, Cancer research.

Nonoverlapping T-Cell Receptor Repertoires Lymphocyte-defined Self-Peptide with Diverse and Melanoma Patients Respond to a Cytotoxic T Updated

P. Romero, P. Walker, D. Valmori, 2001 .

Phase I/II trial testing safety and immunogenicity of the multipeptide IMA950/poly-ICLC vaccine in newly diagnosed adult malignant astrocytoma patients.

A. Hottinger, S. Momjian, P. Walker, 2019, Neuro-oncology.

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma.

S. H. van der Burg, J. Castle, H. Rammensee, 2019, Molecular & cellular proteomics : MCP.

Distinct Structural TCR Repertoires in Naturally Occurring Versus Vaccine-Induced CD8+ T-Cell Responses to the Tumor-Specific Antigen NY-ESO-1

D. Valmori, E. Jäger, J. Cerottini, 2005, Journal of immunotherapy.

Exploratory Study of the Effect of IMA950/Poly-ICLC Vaccination on Response to Bevacizumab in Relapsing High-Grade Glioma Patients

A. Patrikidou, P. Dietrich, V. Dutoit, 2019, Cancers.

SSX antigens as tumor vaccine targets in human sarcoma.

Yao-Tseng Chen, L. Old, D. Valmori, 2003, Cancer immunity.

Combinatorial peptide library‐based identification of peptide ligands for tumor‐reactive cytolytic T lymphocytes of unknown specificity

Clemencia Pinilla, Danila Valmori, Pedro Romero, 2002, European journal of immunology.

Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells

J. Sarkaria, K. Krause, P. Walker, 2021, Communications Biology.

Abstract 2396: IMA950: A novel multi-peptide cancer vaccine for treatment of glioblastoma

H. Rammensee, S. Stevanović, O. Schoor, 2010 .

Humoral and cellular immunogenicity two months after SARS-CoV-2 messenger RNA vaccines in patients with cancer

A. Gayet-Ageron, A. Addeo, P. Roux‐Lombard, 2021, iScience.

Comprehensive metagenomic analysis of glioblastoma reveals absence of known virus despite antiviral-like type I interferon gene response

Tom J. Petty, L. Farinelli, K. Krause, 2014, International journal of cancer.

Polyfunctional HCV‐specific T‐cell responses are associated with effective control of HCV replication

J. Borovička, M. Battegay, E. Bernasconi, 2008, European journal of immunology.

Identification of a miRNA multi-targeting therapeutic strategy in glioblastoma

P. R. Walker, Tom J. Petty, J. Tamburini, 2023, Cell death & disease.

Lentivirus-Mediated RNA Interference of DC-SIGN Expression Inhibits Human Immunodeficiency Virus Transmission from Dendritic Cells to T Cells

M. Wiznerowicz, Y. Kooyk, D. Trono, 2004 .

Lentivirus-Mediated RNA Interference of DC-SIGN Expression Inhibits Human Immunodeficiency Virus Transmission from Dendritic Cells to T Cells

M. Wiznerowicz, D. Trono, T. Geijtenbeek, 2004, Journal of Virology.

First report of clinical responses to immunotherapy in 3 relapsing cases of chordoma after failure of standard therapies

B. Landis, P. Dietrich, V. Dutoit, 2017, Oncoimmunology.

Limits of CD133 as a marker of glioma self‐renewing cells

I. Radovanovic, D. Marino, P. Dietrich, 2009, International journal of cancer.

Everolimus as first-line therapy in non-rapidly progressive metastatic castration resistant prostate cancer (mCRPC)

R. Winterhalder, P. Wild, M. Borner, 2011 .

[Therapeutic vaccination for glioblastoma].

P. Dietrich, V. Dutoit, 2020, Medecine sciences : M/S.