A. Pashine

发表

Rheumatoid Arthritis (RA)-Associated HLA-DR Alleles Form Less Stable Complexes with Class II-Associated Invariant Chain Peptide Than Non-RA-Associated HLA-DR Alleles1

E. Mellins, N. Patil, A. Pashine, 2001, The Journal of Immunology.

Influenza Infection Activation in the Human Response to Dendritic Cells Is Necessary for NK Cell NKp46 and NKG2D Recognition of Infected

P. Parham, D. Cosman, A. Moretta, 2007 .

NKp46 and NKG2D Recognition of Infected Dendritic Cells Is Necessary for NK Cell Activation in the Human Response to Influenza Infection1

Peter Parham, P. Parham, D. Cosman, 2007, The Journal of Immunology.

Accessory molecules for MHC class II peptide loading.

R. Doebele, R. Busch, E. Mellins, 2000, Current opinion in immunology.

Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides.

G. Nolan, R. Doebele, R. Busch, 2003, Immunity.

Stabilization of soluble, low-affinity HLA-DM/HLA-DR1 complexes by leucine zippers.

K. Garcia, R. Busch, E. Mellins, 2002, Journal of immunological methods.

Class II Polymorphism Chain Peptide Affinity as a Constraint on Implicate Class II-Associated Invariant Antigen-Binding Groove of HLA-DR 3 Point Mutations in or Near the Mellins Zaller

D. Zaller, R. Doebele, R. Busch, 2003 .

Point Mutations in or Near the Antigen-Binding Groove of HLA-DR3 Implicate Class II-Associated Invariant Chain Peptide Affinity as a Constraint on MHC Class II Polymorphism1

D. Zaller, R. Doebele, R. Busch, 2003, The Journal of Immunology.

DM influences the abundance of major histocompatibility complex class II alleles with low affinity for class II‐associated invariant chain peptides via multiple mechanisms

R. Busch, C. Macaubas, E. Mellins, 2010, Immunology.

Human Dendritic Cell Expression of HLA-DO Is Subset Specific and Regulated by Maturation1

J. Harding, T. Burster, Andrew W. Lee, 2006, The Journal of Immunology.

Human Cytomegalovirus Alters Localization of MHC Class II and Dendrite Morphology in Mature Langerhans Cells1

T. Burster, Andrew W. Lee, L. Hertel, 2006, The Journal of Immunology.

in of MHC Class II and Dendrite Morphology Human Cytomegalovirus Alters Localization

T. Burster, Andrew W. Lee, L. Hertel, 2006 .

Role of IL-12-Independent and IL-12-Dependent Pathways in Regulating Generation of the IFN-γ Component of T Cell Responses to Salmonella typhimurium1

D. Rajagopal, B. John, A. Pashine, 2002, Journal of Immunology.

Targeting the innate immune response with improved vaccine adjuvants

Jeffrey B Ulmer, J. Ulmer, N. Valiante, 2005, Nature Medicine.

Inhibition of T Cell Proliferation by Macrophage Tryptophan Catabolism

D. Munn, Ebrahim Shafizadeh, A. Mellor, 1999, The Journal of experimental medicine.

Determination of the HLA-DM interaction site on HLA-DR molecules.

R. Doebele, R. Busch, E. Mellins, 2000, Immunity.

Hydrogen/deuterium exchange mass spectrometry and computational modeling reveal a discontinuous epitope of an antibody/TL1A Interaction

S. Krystek, M. Srinivasan, R. Graziano, 2018, mAbs.

Human cytomegalovirus decreases constitutive transcription of MHC class II genes in mature Langerhans cells by reducing CIITA transcript levels.

J. Harding, Andrew W. Lee, L. Hertel, 2011, Molecular Immunology.

Alleles Peptide Than Non-RA-Associated HLA-DR with Class II-Associated Invariant Chain ComplexesHLA-DR Alleles Form Less Stable Rheumatoid Arthritis ( RA )-Associated

H. Mcconnell, E. Mellins, N. Patil, 2001 .

Th1 dominance in the immune response to live Salmonella typhimurium requires bacterial invasiveness but not persistence.

B. John, A. Pashine, S. Rath, 1999, International immunology.

Innate immune mechanisms and the identification of immune potentiators as vaccine adjuvants

J. Ulmer, N. Valiante, A. Pashine, 2006, Immunopotentiators in Modern Vaccines.

WITHDRAWN: Failed efficacy of soluble human CD83-Ig in allogeneic mixed lymphocyte reactions and experimental autoimmune encephalomyelitis: implications for a lack of therapeutic potential?

S. Peng, Jinzhi Chen, U. Göpfert, 2007, Immunology letters.

Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy

Johannes C. Hermann, C. Lukacs, Seng-Lai Tan, 2013, Arthritis Research & Therapy.

A Robust High Throughput Platform to Generate Functional Recombinant Monoclonal Antibodies Using Rabbit B Cells from Peripheral Blood

I. Thorey, S. Klostermann, S. Offner, 2014, PloS one.

RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents

Daigen Xu, J. Demartino, S. Narula, 2012, Journal of Pharmacology and Experimental Therapeutics.

Thymic stromal lymphopoietin receptor blockade reduces allergic inflammation in a cynomolgus monkey model of asthma.

Donavan T. Cheng, S. Apparsundaram, H. Bitter, 2013, The Journal of allergy and clinical immunology.

JPET #187740 RN486 [6-Cyclopropyl-8-fluoro-2-(2-hydroxymethyl-3-{1-methyl-5-[5-(4-methyl- piperazin-1-yl)-pyridin-2-ylamino]-6-oxo-1,6-dihydro-pyridin-3-yl}-phenyl)-2H- isoquinolin-1-one], a Selective Bruton’s Tyrosine Kinase (Btk) Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis

Daigen Xu, J. Demartino, S. Narula, 2011 .

Blockade of thymic stromal lymphopoietin receptor (TSLPR) reduces atopic inflammation in a cynomolgus monkey model of asthma

Donavan T. Cheng, S. Apparsundaram, H. Bitter, 2012 .

OR.50. Human Cytomegalovirus Alters Localization of Mhc Class Ii and Dendrite Morphology in Mature Langerhans Cells

T. Burster, Andrew W. Lee, L. Hertel, 2006 .

RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents

Daigen Xu, S. Narula, D. Srinivasan, 2012, Journal of Pharmacology and Experimental Therapeutics.

The candidate lupus susceptibility gene Ifi202a is largely dispensable for B-cell function.

S. Peng, M. G. Gubbels Bupp, A. Pashine, 2008, Rheumatology.