R. Arch

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Cutting Edge: Distinct Motifs Within CD28 Regulate T Cell Proliferation and Induction of Bcl-XL1

A. Shaw, N. Savage, S. Kimzey, 2001, The Journal of Immunology.

Participation in normal immune responses of a metastasis-inducing splice variant of CD44.

P. Herrlich, M. Zöller, R. Arch, 1992, Science.

Translocation of TRAF proteins regulates apoptotic threshold of cells.

C. Thompson, R. Gedrich, R. Arch, 2000, Biochemical and biophysical research communications.

4-1BB and Ox40 Are Members of a Tumor Necrosis Factor (TNF)-Nerve Growth Factor Receptor Subfamily That Bind TNF Receptor-Associated Factors and Activate Nuclear Factor κB

C. Thompson, R. Arch, C. Thompson, 1998, Molecular and Cellular Biology.

Expression of CD30 and Ox40 on T lymphocyte subsets is controlled by distinct regulatory mechanisms

J. Green, R. Arch, Holly M. Toennies, 2004, Journal of leukocyte biology.

Cd44 and Splice Variants of Cd44 in Normal Differentiation and Tumor Progression

J. Sleeman, P. Herrlich, M. Zöller, 1993 .

Inhibition of VEGFR-2 Reverses Type 1 Diabetes in NOD Mice by Abrogating Insulitis and Restoring Islet Function

G. Szot, J. Bluestone, M. Atkinson, 2013, Diabetes.

Regulation of lipopolysaccharide-induced increases in neutrophil glucose uptake.

D. Link, S. Brody, Z. Zhou, 2007, American journal of physiology. Lung cellular and molecular physiology.

Development of a bispecific F(ab′)2 conjugate against the complement receptor CR3 of macrophages and a variant CD44 antigen of rat pancreatic adenocarcinoma for redirecting macrophage-mediated tumor cytotoxicity

M. Zöller, R. Arch, S. Matzku, 1996, Cancer Immunology, Immunotherapy.

TRAF4 functions as an intermediate of GITR-induced NF-κB activation

R. Arch, E. Esparza, 2004, Cellular and Molecular Life Sciences CMLS.

A chemotactic peptide from laminin alpha 5 functions as a regulator of inflammatory immune responses via TNF alpha-mediated signaling.

R. Senior, J. Miner, T. Adair-Kirk, 2005, Journal of immunology.

Prevention o f Tumor Metastasis Formation by Anti-Variant CD 44 By

P. Herrlich, R. Arch, M. Hofmann, 2003 .

Expression of CD44 isoforms carrying metastasis-associated sequences in newborn and adult rats.

P. Herrlich, M. Zöller, R. Arch, 1993, European journal of cancer.

Costimulatory Molecules in T CeII Activation and Transplantation

M. Green, R. Arch, 2004 .

The caspase inhibitor IDN-6556 (PF3491390) improves marginal mass engraftment after islet transplantation in mice.

A. Shapiro, T. Kin, R. Pawlick, 2011, Surgery.

Expression of CD44 variant isoforms in malignant melanoma.

D. Schadendorf, M. Zöller, W. Tilgen, 1996, Clinical cancer research : an official journal of the American Association for Cancer Research.

Transient expression of CD44 variant isoforms in the ontogeny of the rat: ectoderm-, endoderm- and mesoderm-derived cells express different exon combinations.

M. Zöller, P. Möller, Bernd Weber, 1996, Differentiation; research in biological diversity.

Prevention of tumor metastasis formation by anti-variant CD44

P. Herrlich, M. Zöller, R. Arch, 1993, The Journal of experimental medicine.

Therapeutic Approaches for Nonalcoholic Steatohepatitis ( NASH )

R. Arch, Ralf Glatthar, 2021 .

A carboxyfullerene SOD mimetic improves cognition and extends the lifespan of mice

C. Xiong, D. Wozniak, L. Dugan, 2008, Neurobiology of Aging.

Reactive Oxygen Species Are Downstream Products of TRAF-mediated Signal Transduction*

N. Chandel, P. Schumacker, R. Arch, 2001, The Journal of Biological Chemistry.

Regulation of T cell apoptosis

M. Holtzman, J. Green, R. Arch, 2000, Apoptosis.

Lymphocyte survival--the struggle against death.

C. Thompson, R. Arch, C. Thompson, 1999, Annual review of cell and developmental biology.

Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death.

C. Thompson, R. Gedrich, R. Arch, 1998, Genes & development.

Function of tumor necrosis factor receptor family members on regulatory T-cells

R. Arch, 2005, Immunologic research.

Assessment of liver fibrosis progression and regression by a serological collagen turnover profile.

M. Karsdal, D. Schuppan, Z. Goodman, 2019, American journal of physiology. Gastrointestinal and liver physiology.

Extrahepatic platelet-derived growth factor-β, delivered by platelets, promotes activation of hepatic stellate cells and biliary fibrosis in mice.

D. Schuppan, S. Yoshida, S. Ogawa, 2014, Gastroenterology.

Signaling triggered by glucocorticoid-induced tumor necrosis factor receptor family-related gene: regulation at the interface between regulatory T cells and immune effector cells.

R. Arch, E. Esparza, 2006, Frontiers in bioscience : a journal and virtual library.

Tumor Necrosis Factor Receptor (TNFR)-associated Factor 5 Is a Critical Intermediate of Costimulatory Signaling Pathways Triggered by Glucocorticoid-induced TNFR in T Cells*

T. Lindsten, R. Arch, E. Esparza, 2006, Journal of Biological Chemistry.

Glucocorticoid-Induced TNF Receptor, a Costimulatory Receptor on Naive and Activated T Cells, Uses TNF Receptor-Associated Factor 2 in a Novel Fashion as an Inhibitor of NF-κB Activation1

R. Arch, E. Esparza, 2005, The Journal of Immunology.

Glucocorticoid-Induced TNF Receptor Functions as a Costimulatory Receptor That Promotes Survival in Early Phases of T Cell Activation1

R. Arch, E. Esparza, 2005, The Journal of Immunology.

A Chemotactic Peptide from Laminin α5 Functions as a Regulator of Inflammatory Immune Responses via TNFα-mediated Signaling1

R. Senior, J. Miner, T. Adair-Kirk, 2005, The Journal of Immunology.

Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study

E. Winzeler, D. Fidock, M. Phillips, 2018, The Lancet. Infectious diseases.

Characterization of binding mode of action of a blocking anti-platelet-derived growth factor (PDGF)-B monoclonal antibody, MOR8457, reveals conformational flexibility and avidity needed for PDGF-BB to bind PDGF receptor-β.

L. Mosyak, N. Pullen, E. Lavallie, 2015, Biochemistry.

Anti‐PDGF‐B monoclonal antibody reduces liver fibrosis development

B. Violand, J. Masferrer, R. Arch, 2010, Hepatology research : the official journal of the Japan Society of Hepatology.

Metastatic Tumor Cells Mimic Lymphocytes

P. Herrlich, M. Zöller, R. Arch, 1992 .

Intratumoral delivery of immune therapy and gene therapy: the next era for cancer therapy.

R. Arch, Jun Zhang, D. Canton, 2023, Immunotherapy.

Multiplex transcriptional analysis of paraffin-embedded liver needle biopsy from patients with liver fibrosis

Yunqing Ma, Botoul Maqsodi, J. Masferrer, 2012, Fibrogenesis & tissue repair.

CD44 in Normal Differentation and Tumor Progression

P. Herrlich, M. Zöller, K. Heider, 1993 .

Prevention of tumor metastasis formation by anti-variant CD44

P. Herrlich, M. Zöller, R. Arch, 1993, The Journal of experimental medicine.

TRAF4 functions as an intermediate of GITR-induced NF-kappaB activation.

R. Arch, E. Esparza, 2004, Cellular and molecular life sciences : CMLS.

Anti‐PDGF‐B monoclonal antibody reduces liver fibrosis development

B. Violand, J. Masferrer, R. Arch, 2010, Hepatology research : the official journal of the Japan Society of Hepatology.

L. Mosyak, N. Pullen, E. Lavallie, 2015, Biochemistry.