J. Loader

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Mast Cells, FcεRI, and IL-13 Are Required for Development of Airway Hyperresponsiveness after Aerosolized Allergen Exposure in the Absence of Adjuvant1

Xudong Wei, E. Gelfand, E. Hamelmann, 2004, The Journal of Immunology.

Apoptosis induced by ozone and oxysterols in human alveolar epithelial cells.

R. Murphy, R. Mason, J. Loader, 2010, Free radical biology & medicine.

Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.

R. Rancourt, C. White, B. Day, 2010, Free radical biology & medicine.

Role of reactive oxygen and nitrogen species in olfactory epithelial injury by the sulfur mustard analogue 2-chloroethyl ethyl sulfide.

C. White, D. Orlicky, B. Day, 2011, American journal of respiratory cell and molecular biology.

Sarcoendoplasmic reticulum Ca(2+) ATPase. A critical target in chlorine inhalation-induced cardiotoxicity.

Aftab Ahmad, Shama Ahmad, C. White, 2015, American journal of respiratory cell and molecular biology.

Nebulized IFN-gamma inhibits the development of secondary allergic responses in mice.

E. Gelfand, E. Hamelmann, G. Lack, 1996, Journal of immunology.

Tissue plasminogen activator prevents mortality from sulfur mustard analog-induced airway obstruction.

C. White, J. Loader, L. Veress, 2013, American journal of respiratory cell and molecular biology.

Inhibition of cell proliferation by putative metabolites and non-degradable analogs of methotrexate-Y-dimyristoylphosphatidylethanolamine

S. Kinsky, J. Loader, Hashimoto Keiichiro, 1987 .

Bronchiolitis Obliterans and Pulmonary Fibrosis after Sulfur Mustard Inhalation in Rats

C. White, J. Loader, L. Veress, 2018, American journal of respiratory cell and molecular biology.

Estrogen determines sex differences in airway responsiveness after allergen exposure.

E. Gelfand, A. Joetham, A. Dakhama, 2008, American journal of respiratory cell and molecular biology.

Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog

R. Rancourt, C. White, J. Loader, 2015, Pediatric pulmonology.

The Leukotriene B4 Receptor (BLT1) Is Required for Effector CD8+ T Cell-Mediated, Mast Cell-Dependent Airway Hyperresponsiveness1

E. Gelfand, A. Tager, A. Dakhama, 2006, The Journal of Immunology.

Bcl-2 suppresses sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression in cystic fibrosis airways: role in oxidant-mediated cell death.

A. Perraud, S. Randell, Aftab Ahmad, 2009, American journal of respiratory and critical care medicine.

Leukotriene B4 release from mast cells in IgE-mediated airway hyperresponsiveness and inflammation.

M. Tanimoto, E. Gelfand, A. Joetham, 2009, American journal of respiratory cell and molecular biology.

Hyperresponsiveness Cell-Mediated , Mast Cell-Dependent Airway T + Required for Effector CD 8 The Leukotriene B 4 Receptor ( BLT 1 ) Is

E. Gelfand, A. Tager, A. Dakhama, 2006 .

The leukotriene B4 receptor (BLT1) is required for effector CD8+ T cell-mediated, mast cell-dependent airway hyperresponsiveness.

E. Gelfand, A. Tager, A. Dakhama, 2006, Journal of immunology.

Passive transfer of immediate hypersensitivity and airway hyperresponsiveness by allergen-specific immunoglobulin (Ig) E and IgG1 in mice.

E. Gelfand, E. Hamelmann, G. Larsen, 1996, The Journal of clinical investigation.

Airway response to electrical field stimulation in sensitized inbred mice. Passive transfer of increased responsiveness with peribronchial lymph nodes.

E. Gelfand, G. Larsen, H. Renz, 1992, The Journal of clinical investigation.

Increased acetylcholine release in tracheas from allergen-exposed IgE-immune mice.

E. Gelfand, G. Larsen, H. Renz, 1994, The American journal of physiology.

CD23 exhibits negative regulatory effects on allergic sensitization and airway hyperresponsiveness.

D. Conrad, E. Gelfand, James J. Lee, 2000, American journal of respiratory and critical care medicine.

Inhibition of IgE production and normalization of airways responsiveness by sensitized CD8 T cells in a mouse model of allergen-induced sensitization.

E. Gelfand, A. Kupfer, G. Lack, 1994, Journal of immunology.

Modulation of airway responses by prostaglandins in young and fully grown rabbits.

G. Larsen, A. Dakhama, J. Loader, 2007, American journal of physiology. Lung cellular and molecular physiology.

Neuropeptide release from airways of young and fully‐grown rabbits

G. Larsen, A. Dakhama, J. Loader, 2006, Pediatric pulmonology.

Mechanisms determining cholinergic neural responses in airways of young and mature rabbits

G. Larsen, A. Dakhama, J. Loader, 2004, Pediatric pulmonology.

Antiinterleukin-5 antibody prevents airway hyperresponsiveness in a murine model of airway sensitization.

E. Gelfand, James J. Lee, E. Hamelmann, 1997, American journal of respiratory and critical care medicine.

Anti-CD86 (B7.2) treatment abolishes allergic airway hyperresponsiveness in mice.

E. Hamelmann, G. Cieslewicz, A. Joetham, 1999, American journal of respiratory and critical care medicine.

Human respiratory syncytial virus produces prolonged alterations of neural control in airways of developing ferrets.

G. Prince, G. Larsen, J. Loader, 1998, American journal of respiratory and critical care medicine.

Nebulized but not parenteral IFN-gamma decreases IgE production and normalizes airways function in a murine model of allergen sensitization.

E. Gelfand, G. Lack, G. Larsen, 1994, Journal of immunology.

Spontaneous airway hyperresponsiveness in estrogen receptor-alpha-deficient mice.

K. Korach, E. Gelfand, E. Jacobs, 2007, American journal of respiratory and critical care medicine.

Alteration of airway neuropeptide expression and development of airway hyperresponsiveness following respiratory syncytial virus infection.

E. Gelfand, A. Joetham, G. Larsen, 2005, American journal of physiology. Lung cellular and molecular physiology.

Regulation of airway hyperresponsiveness by calcitonin gene-related peptide in allergen sensitized and challenged mice.

M. Mäkelä, E. Gelfand, G. Larsen, 2002, American journal of respiratory and critical care medicine.

Allergen-specific IgE and IL-5 are essential for the development of airway hyperresponsiveness.

E. Gelfand, E. Hamelmann, J. Schwarze, 1997, American journal of respiratory cell and molecular biology.

Requirement for CD 8 + T Cells in the Deve lopment o f Airway Hyperresponsiveness in a Murine Model o f Airway Sensitization

E. Gelfand, E. Hamelmann, T. Potter, 2003 .

Transcriptome profiling of the newborn mouse lung response to acute ozone exposure.

C. White, A. Dakhama, S. Leach, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Decrease in the airways' nonadrenergic noncholinergic inhibitory system in allergen sensitized rabbits

G. Larsen, J. Loader, G. Colasurdo, 1994, Pediatric pulmonology.

Phosphodiesterase IV and neutral endopeptidase in airways from developing and allergen sensitized rabbits.

G. Larsen, A. Dakhama, J. Loader, 2006, Pulmonary pharmacology & therapeutics.

CD23 deficient mice develop allergic airway hyperresponsiveness following sensitization with ovalbumin.

E. Hamelmann, A. Joetham, H. Kikutani, 1997, American journal of respiratory and critical care medicine.

T cells expressing specific V beta elements regulate immunoglobulin E production and airways responsiveness in vivo

E. Gelfand, G. Larsen, H. Renz, 1993, The Journal of experimental medicine.

Effect of aspiration of milk on mechanisms of neural control in the airways of developing rabbits

G. Larsen, J. Loader, L. Fan, 1997, Pediatric pulmonology.

Human respiratory syncytial virus affects nonadrenergic noncholinergic inhibition in cotton rat airways.

G. Prince, G. Larsen, J. Loader, 1995, The American journal of physiology.

Maturation of nonadrenergic noncholinergic inhibitory system in normal and allergen-sensitized rabbits.

G. Larsen, J. Loader, G. Colasurdo, 1994, The American journal of physiology.

Prevention of the development of immediate hypersensitivity and airway hyperresponsiveness following in vivo treatment with soluble IL-4 receptor.

E. Gelfand, G. Larsen, H. Renz, 1996, International archives of allergy and immunology.

Tissue factor signals airway epithelial basal cell survival via coagulation and protease-activated receptor isoforms 1 and 2.

R. Rancourt, Aftab Ahmad, Shama Ahmad, 2013, American journal of respiratory cell and molecular biology.

Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyperresponsiveness.

E. Gelfand, E. Masuda, J. Lucas, 2006, American journal of respiratory and critical care medicine.

Pretreatment with allergen prevents immediate hypersensitivity and airway hyperresponsiveness.

E. Gelfand, E. Hamelmann, G. Larsen, 1996, American journal of respiratory and critical care medicine.

Iodoacetylated and biotinylated liposomes: effect of spacer length on sulfhydryl ligand binding and avidin precipitability.

S. Kinsky, J. Loader, K. Hashimoto, 1986, Biochimica et biophysica acta.

Transfer of Anti-OVA IgE Production by Vff 8 . 1 / 8 . 2 T Cells

E. Gelfand, G. Larsen, H. Renz, 2003 .

Specific V beta T cell subsets mediate the immediate hypersensitivity response to ragweed allergen.

E. Gelfand, G. Larsen, H. Renz, 1993, Journal of immunology.

Mast Cells, FcεRI, and IL-13 Are Required for Development of Airway Hyperresponsiveness after Aerosolized Allergen Exposure in the Absence of Adjuvant1

Xudong Wei, E. Gelfand, E. Hamelmann, 2004, The Journal of Immunology.

IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization.

M. Jordana, M. Mäkelä, E. Gelfand, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Circumvention of the methotrexate transport system by methotrexate-phosphatidylethanolamine derivatives: effect of fatty acid chain length.

S. Kinsky, J. Loader, 1987, Biochimica et biophysica acta.

Inhibition of cell proliferation and dihydrofolate reductase by liposomes containing methotrexate-dimyristoylphosphatidylethanolamine derivatives and by the glycerophosphorylethanolamine analogs.

S. Kinsky, J. Loader, K. Hashimoto, 1985, Biochimica et biophysica acta.

From the Cover: Catalytic Antioxidant Rescue of Inhaled Sulfur Mustard Toxicity.

C. White, B. Day, J. Loader, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Synthesis and characterization of methotrexate-dimyristoylphosphatidylethanolamine derivatives and the glycerophosphorylethanolamine analogs.

S. Kinsky, J. Loader, K. Hashimoto, 1985, Biochimica et biophysica acta.

Requirement for CD8+ T cells in the development of airway hyperresponsiveness in a marine model of airway sensitization

E. Gelfand, E. Hamelmann, T. Potter, 1996, The Journal of experimental medicine.

Role of glucose in contractility of airway smooth muscle.

J. Loader, J. Souhrada, 1979, Respiration physiology.

Airway tissue plasminogen activator prevents acute mortality due to lethal sulfur mustard inhalation.

R. Rancourt, C. White, J. Loader, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

An alternative procedure for the preparation of immunogenic liposomal model membranes.

S. Kinsky, J. Loader, A. Benson, 1983, Journal of immunological methods.

Spontaneous Airway Hyperresponsiveness in Estrogen Receptor-α–deficient Mice

K. Korach, E. Gelfand, E. Jacobs, 2007 .

Airway obstruction due to bronchial vascular injury after sulfur mustard analog inhalation.

R. Rancourt, C. White, J. Loader, 2010, American journal of respiratory and critical care medicine.

The lung response to ozone is determined by age and is partially dependent on toll-Like receptor 4

C. White, A. Dakhama, J. Loader, 2015, Respiratory Research.

Mice that overexpress Cu/Zn superoxide dismutase are resistant to allergen-induced changes in airway control.

A. Joetham, C. White, G. Larsen, 2000, American journal of physiology. Lung cellular and molecular physiology.

In vitro cell culture model for toxic inhaled chemical testing.

Shama Ahmad, C. White, K. Neeves, 2014, Journal of visualized experiments : JoVE.

Interaction and localization of synthetic nanoparticles in healthy and cystic fibrosis airway epithelial cells: effect of ozone exposure.

B. Rothen‐Rutishauser, Shama Ahmad, C. White, 2012, Journal of aerosol medicine and pulmonary drug delivery.

Synthesis of N-hydroxysuccinimide esters of phosphatidylethanolamine and some properties of liposomes containing these derivatives

S. Kinsky, J. Loader, K. Hashimoto, 1984 .

Phorbol ester activation of phospholipase D in human monocytes but not peripheral blood lymphocytes.

S. Kinsky, J. Loader, S. Benedict, 1989, Biochemical and biophysical research communications.

Ozone enhances pulmonary innate immune response to a Toll-like receptor-2 agonist.

Ivana V. Yang, D. Schwartz, I. Yang, 2013, American journal of respiratory cell and molecular biology.

Mechanisms of cholinergic dysfunction in rabbits following recurrent aspiration of cow's milk *

G. Larsen, J. Loader, G. Colasurdo, 2001, Pediatric pulmonology.

Requirement for CD8+ T cells in the development of airway hyperresponsiveness in a marine model of airway sensitization

E. Gelfand, E. Hamelmann, T. Potter, 1996, The Journal of experimental medicine.

Effect of liposomes sensitized with methotrexate-gamma-dimyristoylphosphatidylethanolamine on cells that are resistant to methotrexate.

S. Kinsky, J. Loader, D. Fernandes, 1986, Biochimica et biophysica acta.