T. Ottenhoff

发表

Identification of HLA class II-restricted determinants of Mycobacterium tuberculosis-derived proteins by using HLA-transgenic, class II-deficient mice.

A. Geluk, K. V. van Meijgaarden, C. David, 1998, Proceedings of the National Academy of Sciences of the United States of America.

A sensitive fluorometric assay for quantitatively measuring specific peptide binding to HLA class I and class II molecules.

J. Drijfhout, A. Geluk, K. V. van Meijgaarden, 1997, Journal of immunological methods.

Immunoglobulin G1 Fc glycosylation as an early hallmark of severe COVID-19

T. Ottenhoff, G. Vidarsson, J. Nouta, 2021, EBioMedicine.

A novel, highly efficient peptide-HLA class I binding assay using unfolded heavy chain molecules: identification of HIV-1 derived peptides that bind to HLA-A*0201 and HLA-A*0301.

J. Drijfhout, A. Geluk, M. Toebes, 1997, Journal of immunological methods.

Differential gene expression of activating Fcγ receptor classifies active tuberculosis regardless of human immunodeficiency virus status or ethnicity.

S. Kaufmann, D. van Baarle, H. Dockrell, 2014, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Diabetes mellitus is strongly associated with tuberculosis in Indonesia.

B. Alisjahbana, M. den Heijer, T. Ottenhoff, 2006, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture

Y. Kamatani, A. Metspalu, M. Kubo, 2022, medRxiv.

Glucocorticoids transform CD40-triggering of dendritic cells into an alternative activation pathway resulting in antigen-presenting cells that secrete IL-10.

R. Offringa, C. Melief, C. van Kooten, 2000, Blood.

Strongly increased efficiency of altered peptide ligands by mannosylation.

J. Drijfhout, F. Koning, A. Geluk, 1998, International immunology.

Susceptibility alleles at HLA-DRB1, -DQA1, and -DQB1 loci in Ethiopian childhood insulin-dependent diabetes mellitus.

B. Roep, M. Giphart, T. Ottenhoff, 1994, Human immunology.

Altered peptide ligands of islet autoantigen Imogen 38 inhibit antigen specific T cell reactivity in human type-1 diabetes.

A. Geluk, B. Roep, K. V. van Meijgaarden, 1998, Journal of autoimmunity.

Immunological Crossreactivity of the Mycobacterium leprae CFP‐10 with its Homologue in Mycobacterium tuberculosis

T. Ottenhoff, K. Franken, A. Geluk, 2004, Scandinavian journal of immunology.

Clip binds to HLA class II using methionine-based, allele-dependent motifs as well as allele-independent supermotifs.

J. Drijfhout, A. Geluk, K. V. van Meijgaarden, 1995, Molecular immunology.

Purification of his-tagged proteins by immobilized chelate affinity chromatography: the benefits from the use of organic solvent.

J. Drijfhout, T. Ottenhoff, K. Franken, 2000, Protein expression and purification.

Cellular, Humoral, and Gamma Interferon Responses to Mycobacterium leprae and BCG Antigens in Healthy Individuals Exposed to Leprosy

P. Converse, J. Ehrenberg, T. Ottenhoff, 1988, Scandinavian journal of immunology.

Identification of a conserved universal Th epitope in HIV-1 reverse transcriptase that is processed and presented to HIV-specific CD4+ T cells by at least four unrelated HLA-DR molecules.

S. H. van der Burg, R. Offringa, J. Drijfhout, 1999, Journal of immunology.

Molecular mimicry in diabetes mellitus: the homologous domain in coxsackie B virus protein 2C and islet autoantigen GAD65 is highly conserved in the coxsackie B-like enteroviruses and binds to the diabetes associated HLA-DR3 molecule

T. Ottenhoff, J. Galama, W. Melchers, 1998, Diabetologia.

Immunization with human papillomavirus type 16 (HPV16) oncoprotein-loaded dendritic cells as well as protein in adjuvant induces MHC class I-restricted protection to HPV16-induced tumor cells.

R. Offringa, J. Drijfhout, C. Melief, 1998, Cancer research.

A Comparative Study on the Effects of rIL‐4, rIL‐2, rIFN‐γ, and rTNF‐α on Specific T‐Cell Non‐Responsiveness to Mycobacterial Antigens in Lepromatous Leprosy Patients in Vitro

T. Ottenhoff, T. Ottenhoff, A. Wondimu, 1990, Scandinavian journal of immunology.

DNA immunization of HLA transgenic mice with a plasmid expressing mycobacterial heat shock protein 65 results in HLA class I- and II-restricted T cell responses that can be augmented by cytokines.

R. Kiessling, A. Geluk, J. Charo, 2001, Human gene therapy.

Limitations of homology searching for identification of T-cell antigens with library derived mimicry epitopes.

J. Drijfhout, A. Geluk, P. V. van Veelen, 1999, Vaccine.

Interleukin-10 promoter single-nucleotide polymorphisms as markers for disease susceptibility and disease severity in leprosy

T. Huizinga, T. Ottenhoff, M. Moraes, 2004, Genes and Immunity.

Identification of biomarkers for tuberculosis disease using a novel dual-color RT–MLPA assay

J. Goeman, S. Kaufmann, L. Finos, 2011, Genes and Immunity.

Human T cell responses to peptides of the Mycobacterium leprae 45‐kD serine‐rich antigen

H. Dockrell, G. Bothamley, T. Ottenhoff, 2002, Clinical and experimental immunology.

HLA-DR binding analysis of peptides from islet antigens in IDDM.

J. Drijfhout, A. Geluk, B. Roep, 1998, Diabetes.

Is there a future for TNF promoter polymorphisms?

T. Ottenhoff, T. Ottenhoff, C. Verweij, 2004, Genes and Immunity.

Repurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacterium tuberculosis and Salmonella enterica infections

T. Ottenhoff, F. Verreck, F. Vrieling, 2021, Scientific Reports.

Assessment of Cross-Reactivity between Mycobacterium bovis and M. kansasii ESAT-6 and CFP-10 at the T-Cell Epitope Level

J. Brown, J. Drijfhout, H. Vordermeier, 2007, Clinical and Vaccine Immunology.

Cationic pH-sensitive liposome-based subunit tuberculosis vaccine induces protection in mice challenged with Mycobacterium tuberculosis.

S. V. D. van den Eeden, A. Geluk, K. V. van Meijgaarden, 2024, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Intrinsic immunogenicity of liposomes for tuberculosis vaccines: effect of cationic lipid and cholesterol.

A. Geluk, K. V. van Meijgaarden, T. Ottenhoff, 2024, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.