I. Pryme

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Interaction between mRNA, ribosomes and the cytoskeleton.

J. Hesketh, I. Pryme, 1991, The Biochemical journal.

Hematopoiesis, myeloid leukemia and growth factors.

I. Pryme, L. C. Olsen, C. Bassøe, 1988, The International journal of biochemistry.

Changes in distribution of actin mRNA in different polysome fractions following stimulation of MPC-11 cells

I. Pryme, A. Johannessen, A. Vedeler, 1995, Molecular and Cellular Biochemistry.

Association of mRNAS and polyribosomes with the cytoskeleton: Potential roles in transport and compartmentalization of mRNAS

J. Hesketh, I. Pryme, 1995 .

SODIUM BUTYRATE STIMULATES THE SYNTHESIS OF FIREFLY LUCIFERASE IN TRANSFECTED CHO CELLS BUT LEVELS OF BiP CHAPERONE ARE UNAFFECTED

I. Winge, I. Pryme, 2002, Cell Biology International.

Ketamine: use in psychiatry, its pharmacology and treatment following intoxication

A. Lund, I. Pryme, O. B. Fasmer, 2021, Minerva Psychiatry.

Quetiapine: An Objective Evaluation of Pharmacology,Clinical Uses and Intoxication

A. Lund, I. Pryme, O. B. Fasmer, 2020 .

Neuroleptic malignant syndrome: an easily overlooked neurologic emergency

A. Lund, I. Pryme, B. Engelsen, 2017, Neuropsychiatric disease and treatment.

Correlation of the effect of feeding upon the cell cycle distribution profiles of MPC-11 cells with the relative appearance of [3H]-choline labeled material in microsomal subfractions and other cell fractions

A. Svardal, I. Pryme, 1980, Molecular and Cellular Biochemistry.

Time-dependent alteration in endoplasmic reticulum membrane profiles during in vitro incubation of Krebs II ascites cells

I. Pryme, A. Fjose, 2004, Molecular and Cellular Biochemistry.

Compartmentation of the rough endoplasmic reticulum

I. Pryme, 1986, Molecular and Cellular Biochemistry.

Comparison of the rate of aminoacylation of tRNA isolated from NMRI mouse liver with tRNA isolated from Krebs II ascites or mouse plasmacytoma cells.

I. Pryme, B. H. Berg, 1981, Cancer letters.

Exhaustive Overview of Dietary Plant Lectins: Prospective Importance in the Mediterranean Diet

I. Pryme, 2021, American Journal of Biomedical Science & Research.

Insulin: signal transmission and short-term effects on the cytoskeleton and protein synthesis.

J. Hesketh, I. Pryme, A. Vedeler, 1992, The International journal of biochemistry.

Competition between the signal sequence and a 3'UTR localisation signal during redirection of beta-globin mRNA to the endoplasmic reticulum: implications for biotechnology

J. Hesketh, A. Tauler, I. Pryme, 1999, Cytotechnology.

The growth of an established murine non-Hodgkin lymphoma tumour is limited by switching to a phytohaemagglutinin-containing diet.

S. Ewen, I. Pryme, A. Pusztai, 1999, Cancer letters.

Ribosomal proteins sustain morphology, function and phenotype in acute myeloid leukemia blasts.

I. Pryme, C. Bassøe, O. Bruserud, 1998, Leukemia research.

The nuclear-associated endoplasmic reticulum.

I. Pryme, 1989, The International journal of biochemistry.

The effect of “shearing” forces during ultracentrifugation on the membrane-bound polysomes associated with light rough microsomes of MPC-11 cells

A. Svardal, I. Pryme, 1980, Molecular Biology Reports.

Improving mammalian cell factories : The selection of signal peptide has a major impact on recombinant protein synthesis and secretion in mammalian cells

B. Stern, I. Pryme, L. C. Olsen, 2007 .

The characterization of free, cytoskeletal and membrane-bound polysomes in Krebs II ascites and 3T3 cells

J. Hesketh, I. Pryme, A. Vedeler, 1991, Molecular and Cellular Biochemistry.

Fractionation of membrane-bound polysomes, free polysomes, and nuclei from tissue-cultured cells.

I. Pryme, P. J. Birckbichler, 1973, European journal of biochemistry.

Synthesis of immunoglobulins by membrane-bound polysomes and free polysomes from plasmacytoma cells.

J. Weltman, R. Dowben, I. Pryme, 1973, European journal of biochemistry.

The isolation of microsomal subfractions of mouse plasmacytoma cells: the effect of salt concentration during nitrogen cavitation.

A. Svardal, I. Pryme, 1978, Analytical biochemistry.

The activities of aminoacyl-tRNA synthetase phosphatase and aminoacyl-tRNA synthetases in MPC-11 and Krebs II ascites cells.

I. Pryme, B. H. Berg, 1991, Cancer letters.

Microfilaments and protein synthesis; effects of insulin.

I. Pryme, A. Vedeler, E. Kirkeeide, 1993, The International journal of biochemistry.

Lithium: a review of pharmacology, clinical uses, and toxicity.

A. Lund, I. Pryme, R. Oruch, 2014, European journal of pharmacology.

Suppression of growth of tumour cell lines in vitro and tumours in vivo by mistletoe lectins.

S. Ewen, I. Pryme, A. Pusztai, 2006, Histology and histopathology.

Dietary mistletoe lectin supplementation and reduced growth of a murine non-Hodgkin lymphoma.

S. Ewen, I. Pryme, A. Pusztai, 2002, Histology and histopathology.

Aspects of the role of the endoplasmic reticulum in protein synthesis.

A. Svardal, I. Pryme, 1980, Sub-cellular biochemistry.

Synthesis and secretion of light-chain immunoglobulin in two successive cycles of synchronized plasmacytoma cells

J. Weltman, R. Dowben, I. Pryme, 1976, The Journal of cell biology.

The stimulation of light chain immunoglobulin synthesis in vitro by 0.5M salt wash of MPC-11 membrane-bound polysomes isolated in the G1 and G2 phases of the cell cycle.

I. Pryme, 1974, Biochemical and biophysical research communications.

Alpha2-macroglobulin binding of trypsin, chymotrypsin, papain, and cationic aspartate aminotransferase.

I. Pryme, T. Boyde, T. Boyde, 1968, Clinica chimica acta; international journal of clinical chemistry.

Ionic Effects on α2-Macroglobulin Binding of Cationic Aspartate Aminotransferase

I. Pryme, T. Boyde, 1968 .

Free, cytoskeletal-bound and membrane-bound polysomes isolated from MPC-11 and Krebs II ascites cells differ in their complement of poly(A) binding proteins

I. Pryme, A. Vedeler, R. Moss, 1994, Molecular and Cellular Biochemistry.

The Sequestration of mRNA in the Cytoskeleton and Other Subcellular Structures

I. Pryme, A. Johannessen, A. Vedeler, 1995 .

A mistletoe lectin (ML-1)-containing diet reduces the viability of a murine non-Hodgkin lymphoma tumor.

S. Ewen, I. Pryme, A. Pusztai, 2004, Cancer detection and prevention.

A diet containing the lectin phytohaemagglutinin (PHA) slows down the proliferation of Krebs II cell tumours in mice.

I. Pryme, A. Pusztai, S. Bardócz, 1994, Cancer letters.

Insulin induces cell adhesion and normal flattened morphology in Krebs II ascites tumour cells.

J. Hesketh, I. Pryme, 1990, Cell biology international reports.

Psychotropic drugs interfere with the tight coupling of polyphosphoinositide cycle metabolites in human platelets: a result of receptor-independent drug intercalation in the plasma membrane?

E. Hodneland, H. Holmsen, I. Pryme, 2008, Biochimica et biophysica acta.

The compartmentalization of protein synthesis: importance of cytoskeleton and role in mRNA targeting.

J. Hesketh, I. Pryme, R. Hovland, 1996, The international journal of biochemistry & cell biology.

An intercalation mechanism as a mode of action exerted by psychotropic drugs: results of altered phospholipid substrate availabilities in membranes?

A. Lund, H. Holmsen, I. Pryme, 2010, Journal of chemical biology.

In thrombin stimulated human platelets Citalopram, Promethazine, Risperidone, and Ziprasidone, but not Diazepam, may exert their pharmacological effects also through intercalation in membrane phospholipids in a receptor-independent manner

E. Hodneland, H. Holmsen, I. Pryme, 2009, Journal of chemical biology.

Effects of psychotropic drugs on the thrombin-induced liberation of arachidonate in human platelets.

H. Holmsen, I. Pryme, R. Oruch, 2008, Saudi medical journal.

Vectors Encoding Seven Oikosin Signal Peptides Transfected into CHO Cells Differ Greatly in Mediating Gaussia luciferase and Human Endostatin Production although mRNA Levels are Largely Unaffected

B. Stern, I. Pryme, C. Trösse, 2007, Gene regulation and systems biology.

Anti-cancer therapy: diversion of polyamines in the gut

I. Pryme, Susan Bardocz, 2001, European journal of gastroenterology & hepatology.

The phorbol ester 12-0-tetradecanoyl-phorbol-13-acetate and stimulation of 3H-choline incorporation into endoplasmic reticulum membranes and other subcellular fractions of Krebs II ascites cells during in vitro incubation

J. Lillehaug, I. Pryme, A. Fjose, 2004, Molecular and Cellular Biochemistry.

The effect of a phorbol ester on the lipid microviscosity of two endoplasmic reticulum membrane fractions isolated from krebs II ascites cells

I. Pryme, E. Maltseva, N. Palmina, 1991, Journal of cellular biochemistry.

Insulin induces changes in the subcellular distribution of actin and 5′-nucleotidase

J. Hesketh, I. Pryme, A. Vedeler, 1991, Molecular and Cellular Biochemistry.

The Ideal Antipsychotic: Hybrid between Typical Haloperidol And the Atypical Clozapine Antipsychotic

A. Lund, I. Pryme, R. Oruch, 2015 .

Differences in the incorporation of [3H]-glucosamine into nascent polypeptide chains on free polysomes and two fractions of membrane-bound polysomes in mouse myeloma cells

A. Svardal, I. Pryme, 2004, Molecular Biology Reports.

Purification and characterization of the lytic enzyme N-acetylmuramyl-L-alanine amidase of bacteriophage T7.

I. Pryme, G. Kleppe, H. B. Jensen, 1977, European journal of biochemistry.

The isolation of an inhibitor of T‐even phage lysozyme from E. coli B cells

I. Pryme, H. B. Jensen, P. Joner, 1969, FEBS letters.

The separation of a gene 3.5 directed activity and a lytic activity ("lysozyme") in T7 infected E. coli B cells.

I. Pryme, H. B. Jensen, 1974, Biochemical and biophysical research communications.

Lysozyme synthesis in Escherichia coli B cells infected with Phage T7.

S. Berentsen, I. Pryme, 1970, Biochimica et biophysica acta.

The level of synthesis and secretion of Gaussia princeps luciferase in transfected CHO cells is heavily dependent on the choice of signal peptide.

Stian Knappskog, S. Knappskog, B. Stern, 2007, Journal of biotechnology.

A combination of dietary protein depletion and PHA-induced gut growth reduce the mass of a murine non-Hodgkin lymphoma.

S. Ewen, I. Pryme, A. Pusztai, 1999, Cancer letters.

Dietary phytohaemagglutinin slows down the proliferation of a mouse plasmacytoma (MPC-11) tumour in Balb/c mice.

G. Grant, I. Pryme, A. Pusztai, 1996, Cancer letters.

Phytohemagglutinin-induced gut hyperplasia and the growth of a mouse lymphosarcoma tumor.

G. Grant, I. Pryme, A. Pusztai, 1996, Journal of experimental therapeutics & oncology.

Intracellular levels of polyamines in Krebs II lymphosarcoma cells in mice fed phytohaemagglutinin-containing diets are coupled with altered tumour growth.

G. Grant, I. Pryme, A. Pusztai, 1997, Cancer letters.

Switching between control and phytohaemagglutinin-containing diets affects growth of Krebs II ascites cells and produces differences in the levels of putrescine, spermidine and spermine.

G. Grant, I. Pryme, A. Pusztai, 1995, Cancer letters.

The mRNAs for cyclin A, c-myc and ribosomal proteins L4 and S6 are associated with cytoskeletal-bound polysomes in HepG2 cells.

J. Hesketh, I. Pryme, G. Campbell, 1995, The Biochemical journal.

In Vivo Studies on Possible Health Consequences of Genetically Modified Food and Feed—with Particular Regard to Ingredients Consisting of Genetically Modified Plant Materials

I. Pryme, R. Lembcke, 2003, Nutrition and health.

A Glimpse into Milestones of Insulin Resistance and an Updated Review of Its Management

I. Pryme, R. Oruch, M. Huneif, 2023, Nutrients.

The effects of insulin, cycloheximide and phalloidin on the content of actin and p35 in extracts prepared from the nuclear fraction of Krebs II ascites cells

I. Pryme, A. Vedeler, B. Almås, 1992, Molecular and Cellular Biochemistry.

Ultrastructure and polysome content of the microsomal subfractions of mouse plasmacytoma cells

A. Svardal, I. Pryme, H. Dalen, 1981, Molecular and Cellular Biochemistry.

Specificity of factors isolated from free polysomes and microsomes on in vitro protein synthesis in plasmacytoma cells

I. Pryme, T. S. Eikhom, K. A. Abraham, 1974, Molecular Biology Reports.

The synthesis of light chain immunoglobulin in MPC‐11 cells on only one of two fractions of membrane‐bound polysomes prepared by a combination of nitrogen cavitation/detergent treatment

I. Pryme, 1974, FEBS letters.

Polysomes in various phases of the cell cycle in synchronized plasmacytoma cells.

R. Dowben, I. Pryme, K. A. Abraham, 1973, Experimental cell research.

Domains of rough endoplasmic reticulum (a review)

I. Pryme, 1989, Molecular and Cellular Biochemistry.

Differences in the association of ribosomes with heavy rough and light rough endoplasmic reticulum membranes of MPC-11 cells.

I. Pryme, 1988, Biochimica et biophysica acta.

Beneficial (antiproliferative) effects of different substances

F. Lajolo, M. Genovese, I. Pryme, 2004 .

Drug treatment of insomnia: impact of zopiclone

A. Lund, I. Pryme, O. B. Fasmer, 2022, Gazzetta Medica Italiana Archivio per le Scienze Mediche.

The effects of orally administered L-arginine HCl on the development of myeloma tumours in BABL/c mice following the injection of single cell suspensions, cell aggregates or tumor fragments; and on the growth of two ascites tumour cell lines

I. Pryme, 1978 .

The failure of growth of a mouse myeloma tumour during the course of oral administration of L-arginine-hydrochloride

I. Pryme, 1975 .

Variation in microsomal subfractions obtained from normal animal tissues and transformed cells following cell disruption by nitrogen cavitation

A. Svardal, J. Skorve, I. Pryme, 1981, Molecular and Cellular Biochemistry.

Reducing the availability of polyamines for a developing tumour.

I. Pryme, 2007, Biochemical Society transactions.

The induction of gut hyperplasia by phytohaemagglutinin in the diet and limitation of tumour growth.

S. Ewen, I. Pryme, A. Pusztai, 1998, Histology and histopathology.

E. Hodneland, H. Holmsen, I. Pryme, 2009, Journal of chemical biology.

Enrichment of specific mRNAs in cytoskeletal-bound and membrane-bound polysomes in Chinese hamster ovary cells.

J. Hesketh, A. Tauler, I. Pryme, 1996, Biochemical Society transactions.

In vitro transformation and tumor promotion studies of styrene and styrene oxide.

J. Lillehaug, I. Pryme, R. Djurhuus, 1985, Carcinogenesis.

Insulin and step-up conditions cause a redistribution of polysomes among free, cytoskeletal-bound and membrane-bound fractions in Krebs II ascites cells.

J. Hesketh, I. Pryme, A. Vedeler, 1990, Cell biology international reports.

The migration of labeled phosphatidylcholine from the nuclear-associated endoplasmic reticulum to plasma membranes in L-929 cells

I. Pryme, E. Quarcoo, 1988, Molecular and Cellular Biochemistry.

The effect of insulin on proteins associated with free, cytoskeletal‐bound and membrane‐bound polysome populations.

I. Pryme, A. Vedeler, R. Moss, 1993, Cell biology international.

Compartmentalization of polysomes into free, cytoskeletal-bound and membrane-bound populations.

J. Hesketh, I. Pryme, A. Vedeler, 1991, Biochemical Society Transactions.

Changes in amounts of polysomes in free, cytoskeleton-bound and membrane-bound populations in Krebs II ascites cells subjected to different growth conditions.

I. Pryme, A. Vedeler, E. Kirkeeide, 1991, Biochemical Society Transactions.

Difference in patterns of proteins isolated from polysomes in free, cytoskeleton-bound and membrane-bound fractions in MPC-II cells incubated with insulin.

I. Pryme, A. Vedeler, R. Moss, 1991, Biochemical Society Transactions.

Morphological changes in Krebs II ascites tumour cells induced by insulin are associated with differences in protein composition and altered amounts of free, cytoskeletal-bound and membrane-bound polysomes

I. Pryme, A. Vedeler, E. Kirkeeide, 1992, Molecular and Cellular Biochemistry.

The mapping of three subfractions of endoplasmic reticulum membranes isolated from L-929 cells by the use of spin probes

N. Palmina, I. Pryme, E. Maltseva, 1991, Molecular and Cellular Biochemistry.

Cytochalasin B binding and actin content of endoplasmic reticulum subfractions isolated from L-929 cells.

J. Hesketh, I. Pryme, 1987, Cell biology international reports.

An intercalation mechanism as a mode of action exerted by psychotropic drugs: results of altered phospholipid substrate availabilities in membranes?

A. Lund, H. Holmsen, I. Pryme, 2010, Journal of chemical biology.

Altered distribution profiles of endoplasmic reticulum subfractions after incubation of Krebs II ascites cells with different concentrations of cytochalasin B

I. Pryme, A. Fjose, 1984, Cell biochemistry and function.

The nuclear‐associated endoplasmic reticulum is an early target for the action of the tumor promoter 12‐O‐tetradecanoyl phorbol‐13‐acetate in C3H/10T½ fibroblasts

J. Lillehaug, I. Pryme, A. Fjose, 1983, FEBS letters.

Albumin 3'untranslated region facilitates increased recombinant protein production from Chinese hamster ovary cells.

J. Hesketh, B. Stern, S. Khazaipoul, 2012, Biotechnology journal.

Enhanced protein synthesis and secretion using a rational signal-peptide library approach as a tailored tool

M. Gräfe, B. Stern, I. Pryme, 2011, BMC proceedings.

UTRtech™: Exploiting mRNA Targeting To Increase Protein Secretion From Mammalian Cells

S. Knappskog, J. Hesketh, B. Stern, 2007 .