Jing Yang

发表

Atomic structure of the APC/C and its mechanism of protein ubiquitination

D. Barford, Ziguo Zhang, S. McLaughlin, 2015, Nature.

Building a pseudo-atomic model of the anaphase-promoting complex

D. Barford, P. D. da Fonseca, Ziguo Zhang, 2013, Acta crystallographica. Section D, Biological crystallography.

WD40 domain of Apc1 is critical for the coactivator-induced allosteric transition that stimulates APC/C catalytic activity

D. Barford, Ziguo Zhang, Leifu Chang, 2016, Proceedings of the National Academy of Sciences.

Atomic-Resolution Structures of the APC/C Subunits Apc4 and the Apc5 N-Terminal Domain

D. Barford, N. Cronin, Ziguo Zhang, 2015, Journal of molecular biology.

Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation

D. Barford, L. Clijsters, A. Vertegaal, 2021, Cell reports.

Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10

N. Cronin, Jing Yang, Danni Fan, 2022, bioRxiv.

Ethanol increases sensitivity of oxalate oxidase assays and facilitates direct activity staining in SDS gels

H. Thordal-Christensen, D. Collinge, Ziguo Zhang, 1996, Plant Molecular Biology Reporter.

Molecular mechanism of APC/C activation by mitotic phosphorylation

D. Barford, Suyang Zhang, M. Skehel, 2016, Nature.

Molecular architecture of the augmin complex

Ziguo Zhang, Leifu Chang, Jing Yang, 2022, Nature Communications.

Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere

S. Scheres, Ziguo Zhang, S. McLaughlin, 2022, bioRxiv.

Reversible oxidation of the membrane distal domain of receptor PTPalpha is mediated by a cyclic sulfenamide.

D. Barford, S. Lemeer, M. Slijper, 2007, Biochemistry.

Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation.

D. Barford, B. Hemmings, V. Good, 2002, Molecular cell.

Crystal structure of an activated Akt/Protein Kinase B ternary complex with GSK3-peptide and AMP-PNP

Brian A. Hemmings, D. Barford, B. Hemmings, 2002, Nature Structural Biology.

Molecular basis of APC/C regulation by the spindle assembly checkpoint

D. Barford, M. Skehel, Ziguo Zhang, 2016, Nature.

Multiple Factors Confer Specific Cdc42 and Rac Protein Activation by Dedicator of Cytokinesis (DOCK) Nucleotide Exchange Factors*

D. Barford, Ziguo Zhang, K. Kulkarni, 2011, The Journal of Biological Chemistry.

Crystal structure of the M‐fragment of α‐catenin: implications for modulation of cell adhesion

D. Barford, N. Tonks, P. Dokurno, 2001, The EMBO journal.

Activation of Rho GTPases by DOCK Exchange Factors Is Mediated by a Nucleotide Sensor

C. Marshall, S. Roe, C. Moens, 2009, Science.

Molecular basis for TPR domain‐mediated regulation of protein phosphatase 5

D. Barford, Mark A. Williams, J. Ladbury, 2005, The EMBO journal.

Insights into Degron Recognition by APC/C Coactivators from the Structure of an Acm1-Cdh1 Complex

D. Barford, W. Chao, N. Cronin, 2013, Molecular cell.

Recombinant expression, reconstitution and structure of human anaphase-promoting complex (APC/C).

D. Barford, W. Chao, E. Morris, 2013, The Biochemical journal.

The APC/C targets the Cep152–Cep63 complex at the centrosome to regulate mitotic spindle assembly

D. Barford, Jing Yang, Thomas Tischer, 2021, Journal of cell science.

Mitotic spindle assembly is controlled by the APC/C localized at the centrosome

D. Barford, T. Tischer, Jing Yang, 2020, bioRxiv.

Negative feedback between the APC/C and Cep152 at the centrosome regulates mitotic spindle assembly

D. Barford, T. Tischer, Jing Yang, 2020 .

Cryo-EM structure of a separase-securin complex at near-atomic resolution

T. G. Martin, D. Barford, S. Scheres, 2017, Nature Structural &Molecular Biology.

Molecular architecture and mechanism of the anaphase-promoting complex

D. Barford, Ziguo Zhang, S. McLaughlin, 2014, Nature.

Architecture of the CBF3-Centromere Complex of the Budding Yeast Kinetochore

D. Barford, Ziguo Zhang, S. McLaughlin, 2018, Nature Structural & Molecular Biology.

Cryo-EM structure of the CBF3-core-Ndc10-DBD complex of the budding yeast kinetochore

D. Barford, Ziguo Zhang, S. McLaughlin, 2018 .

Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome

D. Barford, A. Heck, A. Ehrenhofer-Murray, 2019, Nature.

Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome

D. Barford, T. Tischer, Ziguo Zhang, 2022, bioRxiv.

Structure of the DOCK2−ELMO1 complex provides insights into regulation of the auto-inhibited state

D. Barford, Matthew J. Smith, J. Côté, 2020, Nature Communications.

Structure of the DOCK2−ELMO1 complex provides insights into regulation of the auto-inhibited state

D. Barford, Matthew J. Smith, J. Côté, 2020, Nature Communications.

Recombinant expression and reconstitution of multiprotein complexes by the USER cloning method in the insect cell-baculovirus expression system.

D. Barford, Ziguo Zhang, Jing Yang, 2016, Methods.

Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome

A. Heck, A. Ehrenhofer-Murray, Ziguo Zhang, 2019, Nature.

Architecture of the CBF3-Centromere Complex of the Budding Yeast Kinetochore

D. Barford, Ziguo Zhang, S. McLaughlin, 2018, Nature Structural & Molecular Biology.

Mechanism of isoprenylcysteine carboxyl methylation from the crystal structure of the integral membrane methyltransferase ICMT.

D. Barford, I. Manolaridis, Ziguo Zhang, 2011, Molecular cell.

The four canonical tpr subunits of human APC/C form related homo-dimeric structures and stack in parallel to form a TPR suprahelix.

D. Barford, Ziguo Zhang, K. Kulkarni, 2013 .

Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation.

D. Barford, B. Hemmings, V. Good, 2002, Molecular cell.

Structure of the human outer kinetochore KMN network complex

Ziguo Zhang, Jing Yang, D. Bellini, 2023, bioRxiv.

Mechanism of outer kinetochore assembly on microtubules and its regulation by mitotic error correction

Ziguo Zhang, Jing Yang, T. Dendooven, 2023, bioRxiv.

New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/CCDH1:EMI1 complex

Ziguo Zhang, Leifu Chang, Jing Yang, 2023, bioRxiv.

Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation.

V. Good, Jing Yang, Vivienne Thompson, 2002, Molecules and Cells.

The Four Canonical TPR Subunits of Human APC/C Form Related Homo-Dimeric Structures and Stack in Parallel to Form a TPR Suprahelix☆

Ziguo Zhang, Leifu Chang, Jing Yang, 2013, Journal of molecular biology.

Recombinant expression, reconstitution and structure of human anaphase-promoting complex (APC/C).

D. Barford, W. Chao, E. Morris, 2013, Biochemical Journal.

Molecular mechanism of Mad2 conformational conversion promoted by the Mad2-interaction motif of Cdc20

Joe G. Greener, Ziguo Zhang, Jing Yang, 2024, bioRxiv.

Structural mechanism of outer kinetochore Dam1:Ndc80 complex assembly on microtubules

Ziguo Zhang, Jing Yang, T. Dendooven, 2023, Science.

Mechanism of isoprenylcysteine carboxyl methylation from the crystal structure of the integral membrane methyltransferase ICMT.

D. Barford, I. Manolaridis, Ziguo Zhang, 2011, Molecular cell.

The structure of Tap42/alpha4 reveals a tetratricopeptide repeat-like fold and provides insights into PP2A regulation.

D. Barford, S. Roe, D. Brautigan, 2007, Biochemistry.