B. Song

发表

Heme-regulated Inhibitor Kinase-mediated Phosphorylation of Eukaryotic Translation Initiation Factor 2 Inhibits Translation, Induces Stress Granule Formation, and Mediates Survival upon Arsenite Exposure*

Randal J. Kaufman, Paul Anderson, Edward McEwen, 2005, Journal of Biological Chemistry.

The double-stranded RNA-activated protein kinase mediates viral-induced encephalitis.

R. McLendon, E. Wimmer, D. Scheuner, 2003, Virology.

The Cellular Response to Unfolded Proteins in the Endoplasmic Reticulum

D. Scheuner, R. Kaufman, E. McEwen, 2001 .

Glucagon-receptor-antagonism-mediated β-cell regeneration as an effective anti-diabetic therapy.

J. Zha, D. Lindhout, A. Kutach, 2022, Cell reports.

Results Dextran Sodium Sulfate – Induced Colitis Induces ER Stress in Colonic Epithelium

R. Kaufman, J. Wilkinson, B. Song, 2013 .

The unfolded protein response and chemical chaperones reduce protein misfolding and colitis in mice.

R. Kaufman, J. Wilkinson, B. Song, 2013, Gastroenterology.

PKR protects colonic epithelium against colitis through the unfolded protein response and prosurvival signaling

R. Kaufman, B. Song, S. S. Cao, 2012, Inflammatory bowel diseases.

UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

M. Katze, R. Kaufman, Junying Wang, 2008, Developmental cell.

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes.

Subramaniam Pennathur, D. Scheuner, R. Kaufman, 2008, The Journal of clinical investigation.

ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice

R. Kaufman, H. Malhi, Jaeseok Han, 2013, Diabetologia.

Translational control is required for the unfolded protein response and in vivo glucose homeostasis.

E McEwen, S. Bonner-Weir, D. Scheuner, 2001, Molecular cell.

Antioxidants Complement the Requirement for Protein Chaperone Function to Maintain β-Cell Function and Glucose Homeostasis

M. Katze, R. Kaufman, S. Pennathur, 2015, Diabetes.

The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.

D. Scheuner, R. Kaufman, Kezhong Zhang, 2005, The Journal of clinical investigation.

ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress.

R. Kaufman, Junying Wang, Jun Wu, 2007, Developmental cell.

eIF2α phosphorylation is required to prevent hepatocyte death and liver fibrosis in mice challenged with a high fructose diet

R. Kaufman, H. Cha, M. Hatzoglou, 2017, Nutrition & Metabolism.

Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells.

D. Scheuner, R. Kaufman, Junying Wang, 2009, Cell metabolism.

Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis

D. Scheuner, R. Kaufman, F. Schuit, 2005, Nature Medicine.

The unfolded protein response is required to maintain the integrity of the endoplasmic reticulum, prevent oxidative stress and preserve differentiation in β-cells

R. Kaufman, S. Back, B. Song, 2010, Diabetes, obesity & metabolism.

Glucose activates a protein phosphatase-1-mediated signaling pathway to enhance overall translation in pancreatic beta-cells.

M. Bollen, D. Scheuner, R. Kaufman, 2007, Endocrinology.

Molecular and phenotypic characterization of Ire 1 α gene deletion in mouse embryo fibroblasts and pancreatic β cells

D. Scheuner, B. Song, J. Hassler, 2012 .