Laksshman Sundaram

发表

Predicting the clinical impact of human mutation with deep neural networks

Jörg Hakenberg, Jinbo Xu, Serafim Batzoglou, 2018, Nature Genetics.

Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges

Alexander A. Morgan, Yanay Ofran, Predrag Radivojac, 2017, Human mutation.

Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease

Kevin C. Wang, A. Kundaje, Akshay Balsubramani, 2022, Cell.

De novo and inherited variants in coding and regulatory regions in genetic cardiomyopathies

I. Karakikes, Casey A. Gifford, M. Ameen, 2022, Human Genomics.

Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution

Howard Y. Chang, Alexandro E. Trevino, A. Kundaje, 2020, Cell.

Predicting the clinical impact of human mutation with deep neural networks

S. Batzoglou, Jinbo Xu, K. Farh, 2018, Nature Genetics.

The landscape of tolerated genetic variation in humans and primates

Aashish N. Adhikari, S. Batzoglou, Martin Kuhlwilm, 2023, bioRxiv.

Stepwise Generation of Human Induced Pluripotent Stem Cell-Derived Cardiac Pericytes to Model Coronary Microvascular Dysfunction.

M. Ameen, Laksshman Sundaram, Chun Liu, 2023, Circulation.

DeepBipolar: Identifying genomic mutations for bipolar disorder via deep learning

Xiaolin Li, Laksshman Sundaram, Rajendra Rana Bhat, 2017, Human mutation.

The landscape of tolerated genetic variation in humans and primates.

Aashish N. Adhikari, S. Batzoglou, Martin Kuhlwilm, 2023, Science.

CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods

Silvio C. E. Tosatto, Julius O. B. Jacobsen, Nicholas A. Sinnott-Armstrong, 2024, Genome biology.

CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods

Nicholas A. Sinnott-Armstrong, Jonathan M. Mudge, Hui Ting Grace Yeo, 2022, Genome biology.

Transcription factor stoichiometry, motif affinity and syntax regulate single-cell chromatin dynamics during fibroblast reprogramming to pluripotency

A. Kundaje, Akshay Balsubramani, Laksshman Sundaram, 2023, bioRxiv.

Identification of constrained sequence elements across 239 primate genomes

A. Kundaje, Martin Kuhlwilm, H. Clawson, 2023, Nature.

Single-cell chromatin accessibility reveals malignant regulatory programs in primary human cancers

Christopher K. Wong, Ekta Khurana, K. Farh, 2024, Science.