B. Scroggins

发表

An acetylation site in the middle domain of Hsp90 regulates chaperone function.

N. Rosen, L. Neckers, L. Karnitz, 2007, Molecular cell.

Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function.

L. Pearl, P. Piper, W. Stetler-Stevenson, 2010, Molecular cell.

Truncated Plasminogen Activator Inhibitor-1 Protein Protects From Pulmonary Fibrosis Mediated by Irradiation in a Murine Model.

James B. Mitchell, D. Citrin, E. Chung, 2016, International journal of radiation oncology, biology, physics.

Fumarate Hydratase Deﬁciency in Renal Cancer Induces Glycolytic Addiction and Hypoxia-Inducible Transcription Factor 1 (cid:2) Stabilization by Glucose-Dependent Generation of Reactive Oxygen Species (cid:1)

W. Linehan, L. Neckers, J. Trepel, 2009 .

factor-2 in clear cell renal carcinoma

L. Neckers, J. Trepel, Yun-jin Jung, 2010 .

Just say NO: nitric oxide regulation of Hsp90

L. Neckers, B. Scroggins, 2009, EMBO reports.

and T Cell Nonreceptor Protein Tyrosine Function Protein 90-Binding Agent, on T Cell Effects of Geldanamycin, a Heat-Shock

L. Whitesell, R. Matts, S. Hartson, 2013 .

Effects of Geldanamycin, a Heat-Shock Protein 90-Binding Agent, on T Cell Function and T Cell Nonreceptor Protein Tyrosine Kinases1

L. Whitesell, R. Matts, S. Hartson, 2000, The Journal of Immunology.

Kinases and T Cell Nonreceptor Protein Tyrosine FunctionProtein 90-Binding Agent , on T Cell Effects of Geldanamycin , a Heat-Shock

L. Whitesell, R. Matts, S. Hartson, 2000 .

Effects of Geldanamycin, a Heat-Shock

R. Matts, S. Hartson, B. Scroggins, 2000 .

Characterization of the interaction of Aha1 with components of the Hsp90 chaperone machine and client proteins.

R. Matts, B. Scroggins, T. Prince, 2012, Biochimica et biophysica acta.

Post-translational modification of heat-shock protein 90: impact on chaperone function

L. Neckers, B. Scroggins, 2007, Expert opinion on drug discovery.

p50(cdc37) is a nonexclusive Hsp90 cohort which participates intimately in Hsp90-mediated folding of immature kinase molecules.

R. Matts, W. Huang, S. Hartson, 2000, Biochemistry.

Hsp90 Regulates p50 cdc37 Function during the Biogenesis of the Active Conformation of the Heme-regulated eIF2α Kinase*

N. Grammatikakis, Jane-Jane Chen, S. Uma, 2001, The Journal of Biological Chemistry.

Post-translational modification and conformational state of Heat Shock Protein 90 differentially affect binding of chemically diverse small molecule inhibitors

D. Bolon, L. Neckers, Tony Taldone, 2013, Oncotarget.

Posttranslational modification and conformational state of heat shock protein 90 differentially affect binding of chemically diverse small molecule inhibitors.

D. Bolon, L. Neckers, Tony Taldone, 2013 .

Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine.

Y. Miyata, L. Neckers, J. Trepel, 2012, Molecular cell.

Mesenchymal stem cells inhibit cutaneous radiation‐induced fibrosis by suppressing chronic inflammation

D. Citrin, E. Chung, J. Horton, 2013, Stem cells.

Fumarate Hydratase Deficiency in Renal Cancer Induces Glycolytic Addiction and Hypoxia-Inducible Transcription Factor 1α Stabilization by Glucose-Dependent Generation of Reactive Oxygen Species

W. Linehan, L. Neckers, J. Trepel, 2009, Molecular and Cellular Biology.

Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90.

L. Neckers, G. Colombo, M. Meli, 2009, The Journal of clinical investigation.

A small molecule cell-impermeant Hsp90 antagonist inhibits tumor cell motility and invasion

L. Neckers, J. Trepel, F. Koga, 2008, Oncogene.

Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality.

W. Linehan, L. Neckers, J. Trepel, 2013, Cancer cell.

Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants

L. Neckers, J. Trepel, T. Kijima, 2015, PloS one.

Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent

W. Linehan, L. Neckers, W. Linehan, 2015, Oncotarget.

Arthropod venom citrate inhibits phospholipase A2.

C. Ownby, P. West, B. Scroggins, 1995, Toxicon : official journal of the International Society on Toxinology.

Mithramycin A Enhances Tumor Sensitivity to Mitotic Catastrophe Resulting From DNA Damage.

W. Linehan, D. Citrin, Shilpa Patil, 2018, International journal of radiation oncology, biology, physics.

Senescence-associated tumor growth is promoted by 12-Lipoxygenase

U. Shankavaram, D. Citrin, Shilpa Patil, 2022, Aging.

Differential inhibition of Hsc70 activities by two Hsc70-binding peptides.

V. Thulasiraman, S. Uma, R. Matts, 2002, Biochemistry.

Heat shock protein 90α (HSP90α), a substrate and chaperone of DNA-PK necessary for the apoptotic response

K. Kohn, Y. Pommier, L. Neckers, 2012, Proceedings of the National Academy of Sciences.

High affinity binding of Hsp90 is triggered by multiple discrete segments of its kinase clients.

S. Uma, R. Matts, B. Yun, 2003, Biochemistry.

Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain

L. Neckers, J. Buchner, M. Mayer, 2009, Nature Structural &Molecular Biology.

Transforming Growth Factor Alpha is a Critical Mediator of Radiation Lung Injury

D. Citrin, E. Chung, J. Horton, 2014, Radiation research.

Hyperpolarized [1-13C]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect

James B. Mitchell, D. Citrin, M. Matsuo, 2018, Clinical Cancer Research.

IL-13 is a therapeutic target in radiation lung injury

D. Citrin, T. Wynn, E. Chung, 2016, Scientific Reports.

Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers

P. Meltzer, M. Wei, C. Ricketts, 2018, Oncotarget.

Emetine Promotes von Hippel-Lindau-Independent Degradation of Hypoxia-Inducible Factor-2α in Clear Cell Renal Carcinoma

L. Neckers, J. Trepel, Yun-jin Jung, 2010, Molecular Pharmacology.

Hsp 90 Regulates p 50 cdc 37 Function during the Biogenesis of the Active Conformation of the Heme-regulated eIF 2 a Kinase *

N. Grammatikakis, Jane-Jane Chen, S. Uma, 2000 .

Functional proteomic screens reveal an essential extracellular role for hsp90α in cancer cell invasiveness

L. Neckers, C. Unger, L. Ilag, 2004, Nature Cell Biology.