K. Kozarsky

发表

Prevalence of Anti–Adeno-Associated Virus Serotype 8 Neutralizing Antibodies and Arylsulfatase B Cross-Reactive Immunologic Material in Mucopolysaccharidosis VI Patient Candidates for a Gene Therapy Trial

N. Brunetti‐Pierri, G. Andria, Pamela Claudiani, 2015, Human gene therapy.

Transcytosis of Lipoprotein Lipase across Cultured Endothelial Cells Requires Both Heparan Sulfate Proteoglycans and the Very Low Density Lipoprotein Receptor*

D. Strickland, S. Pillarisetti, I. Goldberg, 2001, The Journal of Biological Chemistry.

THE T LYMPHOCYTE STRUCTURE CD60 CONTAINS A SIALYLATED CARBOHYDRATE EPITOPE THAT IS EXPRESSED ON BOTH GANGLIOSIDES AND GLYCOPROTEINS

A. Abe, J. Shayman, D. Fox, 2001, Immunological investigations.

The A9 antigen associated with aggressive human squamous carcinoma is structurally and functionally similar to the newly defined integrin alpha 6 beta 4.

C. Van Waes, T. Carey, K. Kozarsky, 1991, Cancer research.

The A9 Antigen Associated with Aggressive Human Squamous Carcinoma Is Structurally and Functionally Similar to the Newly Defined Integrin α6β4

C. Waes, T. Carey, K. Kozarsky, 1991 .

Analysis of the synthesis, intracellular sorting, and function of glycoproteins using a mammalian cell mutant with reversible glycosylation defects.

D. Kingsley, M. Krieger, L. Hobbie, 1989, Methods in cell biology.

Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse.

D. Rader, M. Krieger, K. Kozarsky, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Hypochlorite-modified High Density Lipoprotein, a High Affinity Ligand to Scavenger Receptor Class B, Type I, Impairs High Density Lipoprotein-dependent Selective Lipid Uptake and Reverse Cholesterol Transport*

A. Hammer, K. Kozarsky, G. Marsche, 2002, The Journal of Biological Chemistry.

Message therapy: gene therapy that targets mRNA sequence and stability.

L. Couture, K. Kozarsky, 1997, American journal of human genetics.

Expression and regulation of human low-density lipoprotein receptors in Chinese hamster ovary cells

R. Sege, M. Krieger, D. Nelson, 1984, Nature.

Use of a mutant cell line to study the kinetics and function of O-linked glycosylation of low density lipoprotein receptors.

D. Kingsley, M. Krieger, K. Kozarsky, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis.

S. Kliewer, T. Mansfield, J. Bisi, 2003, Genes & development.

Prevention of Neurocognitive Deficiency in Mucopolysaccharidosis Type II Mice by Central Nervous System-Directed, AAV9-Mediated Iduronate Sulfatase Gene Transfer.

W. Low, R. McIvor, Zhenhong Nan, 2017, Human gene therapy.

Fibrates Down-regulate Hepatic Scavenger Receptor Class B Type I Protein Expression in Mice*

A. Rigotti, G. Luc, J. Miquel, 2003, The Journal of Biological Chemistry.

Overexpression of SR-BI by Adenoviral Vector Reverses the Fibrateinduced Hypercholesterolemia of Apolipoprotein E-deficient Mice*

J. Borensztajn, K. Kozarsky, T. Fu, 2003, Journal of Biological Chemistry.

Scavenger Receptor Class B, Type I-mediated [3H]Cholesterol Efflux to High and Low Density Lipoproteins Is Dependent on Lipoprotein Binding to the Receptor*

M. Krieger, K. Kozarsky, Xiangjun Gu, 2000, The Journal of Biological Chemistry.

Influence of the HDL receptor SR-BI on atherosclerosis.

M. Krieger, K. Kozarsky, Karen Kozarsky, 1999, Current opinion in lipidology.

Characterization of a family of gamma-ray-induced CHO mutants demonstrates that the ldlA locus is diploid and encodes the low-density lipoprotein receptor

R. Sege, M. Krieger, K. Kozarsky, 1986, Molecular and cellular biology.

DNA-mediated transfer of a human gene required for low-density lipoprotein receptor expression and for multiple Golgi processing pathways

R. Sege, D. Kingsley, M. Krieger, 1986, Molecular and cellular biology.

Intravenous delivery for treatment of mucopolysaccharidosis type I: A comparison of AAV serotypes 9 and rh10

L. Belur, R. McIvor, T. Tran, 2020, Molecular genetics and metabolism reports.

Prolongation of adenoviral transgene expression in mouse liver by T lymphocyte subset depletion.

R. DeMatteo, J. Markmann, S. Raper, 1996, Gene therapy.

Gene therapy for cardiovascular disease.

K. Kozarsky, 2001, Current opinion in pharmacology.

Unusual forms of low density lipoprotein receptors in hamster cell mutants with defects in the receptor structural gene

M. Krieger, K. Kozarsky, H. Brush, 1986, The Journal of cell biology.

Atherosclerosis in the Cholesterol-Fed LDL Receptor Gene Transfer and Hepatic Overexpression of the HDL Receptor SR-BI Reduces

M. Krieger, K. Kozarsky, M. Donahee, 2000 .

The lipidation status of acute-phase protein serum amyloid A determines cholesterol mobilization via scavenger receptor class B, type I.

J. Raynes, K. Kozarsky, G. Marsche, 2007, The Biochemical journal.

Selective cholesteryl ester uptake from high density lipoprotein by human first trimester and term villous trophoblast cells.

G. Desoye, A. Hammer, K. Kozarsky, 2003, Placenta.

Scavenger receptor class B, type I on non-malignant and malignant human epithelial cells mediates cholesteryl ester-uptake from high density lipoproteins.

A. Hammer, K. Kozarsky, C. Wadsack, 2003, The international journal of biochemistry & cell biology.

Sterol carrier protein 2 gene transfer changes lipid metabolism and enterohepatic sterol circulation in mice.

A. Rigotti, J. Miquel, F. Nervi, 2000, Gastroenterology.

Hepatic expression of the catalytic subunit of the apolipoprotein B mRNA editing enzyme (apobec-1) ameliorates hypercholesterolemia in LDL receptor-deficient rabbits.

N. Davidson, James M. Wilson, J. Wilson, 1996, Human gene therapy.

Restoration of LDL receptor activity in mutant cells by intercellular junctional communication.

D. Kingsley, M. Krieger, L. Hobbie, 1987, Science.

Three types of low density lipoprotein receptor-deficient mutant have pleiotropic defects in the synthesis of N-linked, O-linked, and lipid- linked carbohydrate chains

D. Kingsley, M. Krieger, K. Kozarsky, 1986, The Journal of cell biology.

Genetic analysis of receptor-mediated endocytosis

R. Sege, D. Kingsley, M. Krieger, 1985 .

encodes the low-density lipoprotein receptor. demonstrates that the ldlA locus is diploid and gamma-ray-induced CHO mutants Characterization of a family of

R. Sege, M. Krieger, K. Kozarsky, 2013 .

Abnormal intracellular sorting of O-linked carbohydrate-deficient interleukin-2 receptors

M. Krieger, S. Dower, K. Kozarsky, 1988, Molecular and cellular biology.

Localization of the steroidogenic acute regulatory protein in human tissues.

E. Furth, M. Kiriakidou, J. Strauss, 1997, The Journal of clinical endocrinology and metabolism.

The Very Low Density Lipoprotein Receptor Mediates the Cellular Catabolism of Lipoprotein Lipase and Urokinase-Plasminogen Activator Inhibitor Type I Complexes (*)

D. Strickland, C. Maccalman, K. McCrae, 1995, The Journal of Biological Chemistry.

ReGenX AAV Vector Technology: a tool for in vivo screening

K. Kozarsky, 2010 .

Gene therapy of hypercholesterolemic disorders.

J. Wilson, K. Kozarsky, 1995, Trends in cardiovascular medicine.

Gene transfer technology

K. Kozarsky, 2006 .

A novel pathway of human T lymphocyte activation. Identification by a monoclonal antibody generated against a rheumatoid synovial T cell line.

D. Fox, K. Kozarsky, L. Kan, 1988, Journal of immunology.

Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine.

B. Walker, J. Sodroski, M. Krieger, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Gene therapy: adenovirus vectors.

J. Wilson, K. Kozarsky, J M Wilson, 1993, Current opinion in genetics & development.

Molecular cloning of a novel human leukemia-associated gene. Evidence of conservation in animal species.

J. Strahler, S. Hanash, F. Lottspeich, 1989, The Journal of biological chemistry.

Adenovirus-mediated correction of the genetic defect in hepatocytes from patients with familial hypercholesterolemia

M. Grossman, K. Kozarsky, J. M. Wilson, 1993, Somatic cell and molecular genetics.

A model system for in vivo gene transfer into the central nervous system using an adenoviral vector

Blake J. Roessler, Beverly L. Davidson, Edward D. Allen, 1993, Nature Genetics.

In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses.

J. Wilson, S. Raper, S. Raper, 1994, The Journal of biological chemistry.

Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1–deleted adenoviruses

M. Perricaudet, James M. Wilson, Yiping Yang, 1993, Nature Genetics.

A tetracycline‐regulated adenoviral expression system for in vivo delivery of transgenes to lung and liver

D. Rader, U. Tietge, K. Kozarsky, 2003, The journal of gene medicine.

Reversible defects in O-linked glycosylation and LDL receptor expression in a UDP-Gal UDP-GalNAc 4-epimerase deficient mutant

D. Kingsley, M. Krieger, K. Kozarsky, 1986, Cell.

A method for monoclonal antibody isotype switching: anti-CD60 VH expression in a heavy chain-deficient hybridoma variant.

M. Kaminski, D. Fox, K. Kozarsky, 1995, Hybridoma.

Efficient catheter-mediated gene transfer into the heart using replication-defective adenovirus.

James M. Wilson, J. Wilson, J. Leiden, 1994, Gene therapy.

Neurologic Recovery in MPS I and MPS II Mice by AAV9-Mediated Gene Transfer to the CNS after the Development of Cognitive Dysfunction.

L. Belur, K. Kozarsky, Alexander Temme, 2022, Human gene therapy.

Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein.

J. Sodroski, M. Krieger, W. Haseltine, 1989, Journal of acquired immune deficiency syndromes.

Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels

E. Edelman, A. Rigotti, M. Krieger, 1997, Nature.

Comparative Effectiveness of Intracerebroventricular, Intrathecal, and Intranasal Routes of AAV9 Vector Administration for Genetic Therapy of Neurologic Disease in Murine Mucopolysaccharidosis Type I

W. Low, L. Belur, R. McIvor, 2021, Frontiers in Molecular Neuroscience.

Intranasal Adeno-Associated Virus Mediated Gene Delivery and Expression of Human Iduronidase in the Central Nervous System: A Noninvasive and Effective Approach for Prevention of Neurologic Disease in Mucopolysaccharidosis Type I.

W. Low, L. Belur, R. McIvor, 2017, Human gene therapy.

Delivery of an Adeno-Associated Virus Vector into Cerebrospinal Fluid Attenuates Central Nervous System Disease in Mucopolysaccharidosis Type II Mice.

James M. Wilson, Nathan Katz, Hongwei Yu, 2016, Human gene therapy.

Non-invasive intravenous administration of AAV9 transducing iduronate sulfatase leads to global metabolic correction and prevention of neurologic deficits in a mouse model of Hunter syndrome

W. Low, L. Belur, R. McIvor, 2023, Molecular genetics and metabolism reports.

Transduction of human trophoblast cells by recombinant adenoviruses is differentiation dependent.

E. Furth, A. Omigbodun, C. Coutifaris, 1996, Biology of reproduction.

The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor.

J. Fallon, D. Strickland, K. Kozarsky, 1997, The Journal of clinical investigation.

Effects of hepatic expression of the high-density lipoprotein receptor SR-BI on lipoprotein metabolism and female fertility.

A. Rigotti, M. Krieger, M. Morales, 2006, Endocrinology.

The HDL receptor SR-BI: a new therapeutic target for atherosclerosis?

A. Rigotti, S. Acton, K. Kozarsky, 1999, Molecular medicine today.

An anti-CD2 monoclonal antibody that both inhibits and stimulates T cell activation recognizes a subregion of CD2 distinct from known ligand-binding sites.

D. Fox, K. Kozarsky, G. Allada, 1993, Cellular immunology.

Three types of low density lipoprotein receptor-deficient mutant have pleiotropic defects in the synthesis of N-linked, O-linked, and lipid- linked carbohydrate chains

D. Kingsley, M. Krieger, K. Kozarsky, 1986, The Journal of cell biology.