B. Ladenheim

B. Ladenheim, S. Jayanthi, Xiaoling Deng, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Delta opioid peptide [D-Ala2,D-leu5]enkephalin blocks the long-term loss of dopamine transporters induced by multiple administrations of methamphetamine: involvement of opioid receptors and reactive oxygen species.

A. Andrews, J. Cadet, L. Tsao, 1998, The Journal of pharmacology and experimental therapeutics.

Monoamine Oxidases Regulate Telencephalic Neural Progenitors in Late Embryonic and Early Postnatal Development

M. Mattson, J. Cadet, Kevin S. Chen, 2010, The Journal of Neuroscience.

CAMKII-conditional deletion of histone deacetylase 2 potentiates acute methamphetamine-induced expression of immediate early genes in the mouse nucleus accumbens

J. Cadet, O. V. Torres, B. Ladenheim, 2015, Scientific Reports.

Neuronal expression of familial Parkinson's disease A53T α-synuclein causes early motor impairment, reduced anxiety and potential sleep disturbances in mice.

M. Mattson, J. Cadet, Wei-na Cong, 2013, Journal of Parkinson's disease.

Methamphetamine Preconditioning Alters Midbrain Transcriptional Responses to Methamphetamine-Induced Injury in the Rat Striatum

K. Becker, J. Cadet, William W Wood, 2009, PloS one.

Transgenic superoxide dismutase mice differ in opioid-induced analgesia.

C. Epstein, J. Cadet, G. Elmer, 1995, European journal of pharmacology.

Methamphetamine‐Induced Changes in Antioxidant Enzymes and Lipid Peroxidation in Copper/Zinc‐Superoxide Dismutase Transgenic Mice

J. Cadet, B. Ladenheim, S. Jayanthi, 1998, Annals of the New York Academy of Sciences.

Methamphetamine Self-Administration Is Associated with Persistent Biochemical Alterations in Striatal and Cortical Dopaminergic Terminals in the Rat

J. Cadet, S. Goldberg, Z. Justinova, 2010, PloS one.

Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease

M. Mattson, J. Cadet, R. Cutler, 2002, Journal of neurochemistry.

Transgenic mice with high levels of superoxide dismutase activity are protected from the neurotoxic effects of 2'-NH2-MPTP on serotonergic and noradrenergic nerve terminals.

D. Murphy, C. Epstein, A. Andrews, 1996, Molecular pharmacology.

Methamphetamine Administration Causes Death of Dopaminergic Neurons in the Mouse Olfactory Bulb

J. Cadet, B. Ladenheim, S. Jayanthi, 2007, Biological Psychiatry.

Constitutive deletion of translin (Tsn) enhances locomotor response to amphetamine: role of developmental effects

J. Cadet, A. Sawa, J. Baraban, 2020, bioRxiv.

Footshock-Induced Abstinence from Compulsive Methamphetamine Self-administration in Rat Model Is Accompanied by Increased Hippocampal Expression of Cannabinoid Receptors (CB1 and CB2)

J. Cadet, B. Ladenheim, M. McCoy, 2022, Molecular neurobiology.

Elevated body fat increases amphetamine accumulation in brain: evidence from genetic and diet-induced forms of adiposity

J. Cadet, A. Sawa, J. Baraban, 2021, Translational Psychiatry.

Differential effects of binge methamphetamine injections on the mRNA expression of histone deacetylases (HDACs) in the rat striatum.

J. Cadet, B. Ladenheim, M. McCoy, 2014, Neurotoxicology.

Ceruloplasmin deficiency results in an anxiety phenotype involving deficits in hippocampal iron, serotonin, and BDNF

M. Mattson, J. Cadet, E. Unger, 2012, Journal of neurochemistry.

Methamphetamine-induced serotonin neurotoxicity is mediated by superoxide radicals

C. Epstein, J. Cadet, H. Hirata, 1995, Brain Research.

Biochemical Neuroadaptations in the Rat Striatal Dopaminergic System after Prolonged Exposure to Methamphetamine Self-Administration

J. Cadet, D. Goldstein, B. Ladenheim, 2022, International journal of molecular sciences.

Long-Term Protective Effects of Methamphetamine Preconditioning Against Single-Day Methamphetamine Toxic Challenges

J. Cadet, B. Ladenheim, M. McCoy, 2011, Current neuropharmacology.

Methamphetamine Preconditioning: Differential Protective Effects on Monoaminergic Systems in the Rat Brain

J. Cadet, B. Ladenheim, M. McCoy, 2009, Neurotoxicity Research.

Methamphetamine Preconditioning Causes Differential Changes in Striatal Transcriptional Responses to Large Doses of the Drug

W. Wood, K. Becker, J. Cadet, 2011, Dose-response : a publication of International Hormesis Society.

Genome-wide DNA hydroxymethylation identifies potassium channels in the nucleus accumbens as discriminators of methamphetamine addiction and abstinence

J. Cadet, M. Pirooznia, A. Godino, 2017, Molecular Psychiatry.

Genome-wide profiling identifies a subset of methamphetamine (METH)-induced genes associated with METH-induced increased H4K5Ac binding in the rat striatum

K. Becker, J. Cadet, E. Lehrmann, 2013, BMC Genomics.

Chronic cocaine increases κ‐opioid receptor density: Lack of effect by selective dopamine uptake inhibitors

J. Cadet, F. Carroll, B. Ladenheim, 2002, Synapse.

Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis.

J. Cadet, B. Ladenheim, M. McCoy, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of Ecstasy (MDMA)‐induced transcriptional responses in the rat cortex

N. Thiriet, B. Ladenheim, M. McCoy, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Methamphetamine-Induced Dopamine-Independent Alterations in Striatal Gene Expression in the 6-Hydroxydopamine Hemiparkinsonian Rats

W. Wood, K. Becker, J. Cadet, 2010, PloS one.

Involvement of Dopamine Receptors in Binge Methamphetamine-Induced Activation of Endoplasmic Reticulum and Mitochondrial Stress Pathways

J. Cadet, B. Ladenheim, S. Jayanthi, 2011, PloS one.

Methamphetamine Downregulates Striatal Glutamate Receptors via Diverse Epigenetic Mechanisms

A. Bonci, J. Cadet, Hau-Jie Yau, 2014, Biological Psychiatry.

Differential effects of methamphetamine and SCH23390 on the expression of members of IEG families of transcription factors in the rat striatum

J. Cadet, B. Ladenheim, M. McCoy, 2010, Brain Research.

Enhanced Upregulation of CRH mRNA Expression in the Nucleus Accumbens of Male Rats after a Second Injection of Methamphetamine Given Thirty Days Later

K. Becker, J. Cadet, E. Lehrmann, 2014, PloS one.

CREB phosphorylation regulates striatal transcriptional responses in the self-administration model of methamphetamine addiction in the rat

K. Becker, J. Cadet, F. Kobeissy, 2013, Neurobiology of Disease.

Methamphetamine Causes Differential Alterations in Gene Expression and Patterns of Histone Acetylation/Hypoacetylation in the Rat Nucleus Accumbens

K. Becker, J. Cadet, E. Lehrmann, 2012, PloS one.

Chronic methamphetamine exposure suppresses the striatal expression of members of multiple families of immediate early genes (IEGs) in the rat: normalization by an acute methamphetamine injection

J. Cadet, B. Ladenheim, M. McCoy, 2011, Psychopharmacology.

Temporal profiling of methamphetamine‐induced changes in gene expression in the mouse brain: Evidence from cDNA array

J. Cadet, M. Vawter, B. Ladenheim, 2001, Synapse.

Neuroadaptations in the dopaminergic system after active self-administration but not after passive administration of methamphetamine.

J. Cadet, S. Goldberg, B. Ladenheim, 1999, European journal of pharmacology.

A single high dose of methamphetamine increases cocaine self-administration by depletion of striatal dopamine in rats

E. Stein, J. Cadet, Z. Xi, 2009, Neuroscience.

Growth Factor Signals in Neural Cells

K. Becker, J. Cadet, V. Prabhu, 2009, Journal of Biological Chemistry.

Distinct gene expression signatures in the striata of wild‐type and heterozygous c‐fos knockout mice following methamphetamine administration: Evidence from cDNA array analyses

J. Cadet, B. Ladenheim, M. McCoy, 2002, Synapse.

Escalated Oxycodone Self-Administration and Punishment: Differential Expression of Opioid Receptors and Immediate Early Genes in the Rat Dorsal Striatum and Prefrontal Cortex

J. Cadet, B. Ladenheim, M. McCoy, 2020, Frontiers in Neuroscience.

Molecular Adaptations in the Rat Dorsal Striatum and Hippocampus Following Abstinence-Induced Incubation of Drug Seeking After Escalated Oxycodone Self-Administration

J. Schroeder, J. Cadet, B. Ladenheim, 2018, Molecular Neurobiology.

Compulsive methamphetamine self-administration in the presence of adverse consequences is associated with increased hippocampal mRNA expression of cellular adhesion molecules

J. Cadet, B. Ladenheim, S. Jayanthi, 2023, Frontiers in Molecular Neuroscience.

Oxycodone self-administration activates the mitogen-activated protein kinase/ mitogen- and stress-activated protein kinase (MAPK-MSK) signaling pathway in the rat dorsal striatum

J. Cadet, B. Ladenheim, M. McCoy, 2021, Scientific Reports.

Oxycodone self-administration activates the mitogen-activated protein kinase/ mitogen- and stress-activated protein kinase (MAPK-MSK) signaling pathway in the rat dorsal striatum

J. Cadet, B. Ladenheim, M. McCoy, 2020, bioRxiv.

Methamphetamine-induced changes in antioxidant enzymes and lipid peroxidation in copper/zinc-superoxide dismutase transgenic mice.

B. Ladenheim, S. Jayanthi, J. Cadet, 1998, Annals of the New York Academy of Sciences.

Prenatal Interaction of Mutant DISC1 and Immune Activation Produces Adult Psychopathology

C. Ross, J. Cadet, A. Sawa, 2010, Biological Psychiatry.

Differential toxic effects of methamphetamine (METH) and methylenedioxymethamphetamine (MDMA) in multidrug-resistant (mdr1a) knockout mice

J. Cadet, H. Hirata, T. Moran, 1997, Brain Research.

Excessive sugar intake alters binding to dopamine and mu-opioid receptors in the brain

B. Hoebel, G. Schwartz, P. Rada, 2001, Neuroreport.

Dietary restriction mitigates cocaine‐induced alterations of olfactory bulb cellular plasticity and gene expression, and behavior

M. Mattson, Xiangru Xu, K. Becker, 2010, Journal of neurochemistry.

Sex differences in escalated methamphetamine self-administration and altered gene expression associated with incubation of methamphetamine seeking.

J. Schroeder, J. Cadet, B. Ladenheim, 2019, The international journal of neuropsychopharmacology.

Autoradiographic evidence for methamphetamine-induced striatal dopaminergic loss in mouse brain: attenuation in CuZn-superoxide dismutase transgenic mice

C. Epstein, J. Cadet, H. Hirata, 1996, Brain Research.

Increased expression of proenkephalin and prodynorphin mRNAs in the nucleus accumbens of compulsive methamphetamine taking rats

J. Cadet, O. V. Torres, B. Ladenheim, 2016, Scientific Reports.

Chronic Methamphetamine Administration Causes Differential Regulation of Transcription Factors in the Rat Midbrain

N. Volkow, J. Cadet, B. Ladenheim, 2011, PloS one.

Methamphetamine treatment causes delayed decrease in novelty-induced locomotor activity in mice

J. Cadet, Raina Rhoades, B. Ladenheim, 2009, Neuroscience Research.

Neonatal dopamine depletion induces changes in morphogenesis and gene expression in the developing cortex

K. Becker, J. Cadet, B. Ladenheim, 2007, Neurotoxicity Research.

Neurochemical and behavioral comparisons of contingent and non-contingent methamphetamine exposure following binge or yoked long-access self-administration paradigms

J. Cadet, Z. Xi, H. van Praag, 2020, Psychopharmacology.

Differential regulation of dopamine transporter after chronic self-administration of bupropion and nomifensine.

J. Cadet, B. Ladenheim, S. Tella, 1997, The Journal of pharmacology and experimental therapeutics.

Differential Reinforcing Effects of Cocaine and GBR-12909: Biochemical Evidence for Divergent Neuroadaptive Changes in the Mesolimbic Dopaminergic System

A. Andrews, J. Cadet, S. Goldberg, 1996, The Journal of Neuroscience.

Methamphetamine Induces TET1- and TET3-Dependent DNA Hydroxymethylation of Crh and Avp Genes in the Rat Nucleus Accumbens

J. Cadet, V. Bisagno, B. Ladenheim, 2017, Molecular Neurobiology.

Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders

C. Ross, J. Cadet, A. Sawa, 2010, Molecular Psychiatry.

Incubation of Methamphetamine and Palatable Food Craving after Punishment-Induced Abstinence

J. Cadet, Y. Shaham, J. Bossert, 2014, Neuropsychopharmacology.

Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease

Erik Tryggestad, Christopher A. Ross, Wenzhen Duan, 2008, Neurobiology of Disease.

Chronic methylphenidate alters locomotor activity and dopamine transporters differently from cocaine.

J. Cadet, R. Loeloff, B. Ladenheim, 1999, European journal of pharmacology.

Amphetamine causes dopamine depletion and cell death in the mouse olfactory bulb.

J. Cadet, B. Ladenheim, I. Krasnova, 2008, European journal of pharmacology.

Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess.

M. Mattson, K. Becker, J. Cadet, 2007, Endocrinology.

Paroxetine retards disease onset and progression in Huntingtin mutant mice

M. Mattson, Xiangru Xu, J. Cadet, 2004, Annals of neurology.

Chronic co-administration of nicotine and methamphetamine causes differential expression of immediate early genes in the dorsal striatum and nucleus accumbens of Rats

P. Thanos, J. Cadet, N. Volkow, 2013, Neuroscience.

Compulsive methamphetamine taking in the presence of punishment is associated with increased oxytocin expression in the nucleus accumbens of rats

J. Cadet, B. Ladenheim, M. McCoy, 2017, Scientific Reports.

Dietary energy intake modifies brainstem autonomic dysfunction caused by mutant α-synuclein

Emmette R. Hutchison, M. Mattson, J. Cadet, 2013, Neurobiology of Aging.

Methamphetamine Induces Dopamine D1 Receptor-Dependent Endoplasmic Reticulum Stress-Related Molecular Events in the Rat Striatum

K. Becker, J. Cadet, William W Wood, 2009, PloS one.

CuZn-superoxide dismutase (CuZnSOD) transgenic mice show resistance to the lethal effects of methylenedioxyamphetamine (MDA) and of methylenedioxymethamphetamine (MDMA)

C. Epstein, J. Cadet, E. Carlson, 1994, Brain Research.

Serial Analysis of Gene Expression in the Rat Striatum Following Methamphetamine Administration

J. Cadet, Syed F. Ali, B. Ladenheim, 2006, Annals of the New York Academy of Sciences.

Analysis of methamphetamine-induced changes in the expression of integrin family members in the cortex of wild-type and c-fos knockout mice

J. Cadet, B. Ladenheim, M. McCoy, 2002, Neurotoxicity Research.

Neuropeptide Y Protects against Methamphetamine-Induced Neuronal Apoptosis in the Mouse Striatum

R. Palmiter, J. Cadet, S. Goldberg, 2005, The Journal of Neuroscience.

Characterization of Human Cleaved N-CAM and Association with Schizophrenia

G. Sedvall, M. Vawter, W. Freed, 2001, Experimental Neurology.

Environmental enrichment during adolescence regulates gene expression in the striatum of mice

K. Becker, J. Cadet, Xavier Toussay, 2008, Brain Research.

Amphetamine-induced toxicity in dopamine terminals in CD-1 and C57BL/6J mice: complex roles for oxygen-based species and temperature regulation

J. Cadet, M. Huestis, T. Moran, 2001, Neuroscience.

Chronic Methamphetamine Causes Differential Expression of Immediate Early Genes in the Nucleus Accumbens and Midbrain of Rats.

J. Cadet, B. Ladenheim, M. McCoy, 2012, Journal of drug and alcohol research.

Role of dietary iron restriction in a mouse model of Parkinson's disease

M. Mattson, J. Cadet, R. Cutler, 2004, Experimental Neurology.

cDNA array analysis of gene expression profiles in the striata of wild‐type and Cu/Zn superoxide dismutase transgenic mice treated with neurotoxic doses of amphetamine

J. Cadet, B. Ladenheim, M. McCoy, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Amphetamine induces apoptosis of medium spiny striatal projection neurons via the mitochondria‐dependent pathway

J. Cadet, B. Ladenheim, I. Krasnova, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Molecular Adaptations in the Rat Dorsal Striatum and Hippocampus Following Abstinence-Induced Incubation of Drug Seeking After Escalated Oxycodone Self-Administration

J. Schroeder, J. Cadet, B. Ladenheim, 2018, Molecular Neurobiology.

INVOLVEMENT OF OXIDATIVE AND L‐ARGININE‐NO PATHWAYS IN THE NEUROTOXICITY OF DRUGS OF ABUSE IN VITRO

C. Epstein, B. Ladenheim, C. Cerruti, 1995, Clinical and Experimental Pharmacology and Physiology.

A Single Prior Injection of Methamphetamine Enhances Methamphetamine Self-Administration (SA) and Blocks SA-Induced Changes in DNA Methylation and mRNA Expression of Potassium Channels in the Rat Nucleus Accumbens

J. Cadet, O. V. Torres, B. Ladenheim, 2019, Molecular Neurobiology.

(±)-3,4-methylenedioxymethamphetamine and metabolite disposition in plasma and striatum of wild-type and multidrug resistance protein 1a knock-out mice.

J. Cadet, M. Huestis, B. Ladenheim, 2011, Journal of analytical toxicology.

Neurochemical and behavioral comparisons of contingent and non-contingent methamphetamine exposure following binge or yoked long-access self-administration paradigms

H. Praag, J. Cadet, Z. Xi, 2020, Psychopharmacology.

Attenuated response to methamphetamine sensitization and deficits in motor learning and memory after selective deletion of β-catenin in dopamine neurons.

J. Cadet, A. Hoffman, C. Lupica, 2012, Learning & memory.

Increased amphetamine-induced hyperactivity in translin (Tsn) KO mice is driven by elevated adiposity

J. Cadet, A. Sawa, J. Baraban, 2021 .

An Acute Methamphetamine Injection Downregulates the Expression of Several Histone Deacetylases (HDACs) in the Mouse Nucleus Accumbens: Potential Regulatory Role of HDAC2 Expression

J. Cadet, O. V. Torres, B. Ladenheim, 2016, Neurotoxicity Research.

Chronic co-administration of nicotine and methamphetamine causes differential expression of immediate early genes in the dorsal striatum and nucleus accumbens of Rats

P. Thanos, R. Kim, B. Ladenheim, 2013, Neuroscience.

A single high dose of methamphetamine increases cocaine self-administration by depletion of striatal dopamine in rats

Z. Xi, E. Gardner, B. Ladenheim, 2009, Neuroscience.

Differential effects of methamphetamine and SCH23390 on the expression of members of IEG families of transcription factors in the rat striatum

J. Cadet, B. Ladenheim, M. McCoy, 2010, Brain Research.

Methamphetamine Preconditioning Causes Differential Changes in Striatal Transcriptional Responses to Large Doses of the Drug

E. Lehrmann, B. Ladenheim, M. McCoy, 2011, Dose-response : a publication of International Hormesis Society.

-catenin in dopamine neurons

A. Hoffman, C. Lupica, Lufei Shan, 2022 .