Peter Y. Liu

M. Seibel, R. Swerdloff, Peter Y. Liu, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Clinical review 171: The rationale, efficacy and safety of androgen therapy in older men: future research and current practice recommendations.

J. Veldhuis, R. Swerdloff, Peter Y. Liu, 2004, The Journal of clinical endocrinology and metabolism.

Male hormonal contraception: hope and promise.

K. Piotrowska, R. Swerdloff, Peter Y. Liu, 2017, The lancet. Diabetes & endocrinology.

Recombinant human chorionic gonadotropin but not dihydrotestosterone alone stimulates osteoblastic collagen synthesis in older men with partial age-related androgen deficiency.

M. Seibel, David Handelsman, Peter Y. Liu, 2004, The Journal of clinical endocrinology and metabolism.

Sleep and the Testis.

Peter Y. Liu, Peter Y. Liu, N. O'Byrne, 2021, Current opinion in endocrine and metabolic research.

Dynamic Interactions between LH and Testosterone in Healthy Community-Dwelling Men: Impact of Age and Body Composition.

P. Takahashi, J. Veldhuis, F. Roelfsema, 2019, The Journal of clinical endocrinology and metabolism.

Analysis of the impact of intravenous LH pulses versus continuous LH infusion on testosterone secretion during GnRH-receptor blockade.

P. Takahashi, J. Veldhuis, Peter Y. Liu, 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

Neuroendocrine Aging: Pituitary–Gonadal Axis in Males

Steven M. Pincus, D. M. Keenan, P. Takahashi, 2009 .

The aging male hypothalamic–pituitary–gonadal axis: Pulsatility and feedback

D. M. Keenan, A. Iranmanesh, P. Takahashi, 2009, Molecular and Cellular Endocrinology.

Aging attenuates both the regularity and joint synchrony of LH and testosterone secretion in normal men: analyses via a model of graded GnRH receptor blockade.

Steven M. Pincus, D. M. Keenan, A. Iranmanesh, 2006, American journal of physiology. Endocrinology and metabolism.

Age or factors associated with aging attenuate testosterone's concentration-dependent enhancement of the regularity of luteinizing hormone secretion in healthy men.

P. Takahashi, J. Veldhuis, Peter Y. Liu, 2006, The Journal of clinical endocrinology and metabolism.

Graded inhibition of pulsatile luteinizing hormone secretion by a selective gonadotropin-releasing hormone (GnRH)-receptor antagonist in healthy men: evidence that age attenuates hypothalamic GnRH outflow.

A. Iranmanesh, P. Takahashi, J. Veldhuis, 2005, The Journal of clinical endocrinology and metabolism.

Aging in healthy men impairs recombinant human luteinizing hormone (LH)-stimulated testosterone secretion monitored under a two-day intravenous pulsatile LH clamp.

A. Iranmanesh, P. Takahashi, J. Veldhuis, 2005, The Journal of clinical endocrinology and metabolism.

The short-term effects of high-dose testosterone on sleep, breathing, and function in older men.

David Handelsman, B. Yee, Peter Y. Liu, 2003, The Journal of clinical endocrinology and metabolism.

Intimal estrogen receptor (ER)β, but not ERα expression, is correlated with coronary calcification and atherosclerosis in pre- and postmenopausal women

V. Miller, M. Ruan, L. Fitzpatrick, 2006 .

Intimal estrogen receptor (ER)beta, but not ERalpha expression, is correlated with coronary calcification and atherosclerosis in pre- and postmenopausal women.

V. Miller, M. Ruan, L. Fitzpatrick, 2006, The Journal of clinical endocrinology and metabolism.

Early markers of metabolic syndrome in nonoverweight, middle-aged men

David Handelsman, Peter Y. Liu, 2006, Nature Clinical Practice Urology.

Comparison of metabolic effects of the progestational androgens dimethandrolone undecanoate and 11β‐MNTDC in healthy men

Christina Wang, R. Swerdloff, S. Page, 2021, Andrology.

Anabolic and Metabolic Effects of Testosterone and Other Androgens: Direct Effects and Role of Testosterone Metabolic Products

R. Swerdloff, J. Ceponis, Peter Y. Liu, 2017 .

Trough serum testosterone predicts the development of polycythemia in hypogonadal men treated for up to 21 years with subcutaneous testosterone pellets.

David Handelsman, Peter Y. Liu, I. Cunningham, 2010, European journal of endocrinology.

Testosterone protects high-fat/low-carbohydrate diet-induced nonalcoholic fatty liver disease in castrated male rats mainly via modulating endoplasmic reticulum stress.

W. Lee, R. Swerdloff, S. French, 2018, American journal of physiology. Endocrinology and metabolism.

Feedback on LH in Testosterone-Clamped Men Depends on the Mode of Testosterone Administration and Body Composition

P. Takahashi, J. Veldhuis, F. Roelfsema, 2018, Journal of the Endocrine Society.

Male hormonal contraception: so near and yet so far.

R. Mclachlan, Peter Y. Liu, R. McLachlan, 2008, The Journal of clinical endocrinology and metabolism.

Genetic, hormonal, and metabolomic influences on social behavior and sex preference of XXY mice.

J. Jentsch, R. Swerdloff, Peter Y. Liu, 2010, American journal of physiology. Endocrinology and metabolism.

The effects of humanin and its analogues on male germ cell apoptosis induced by chemotherapeutic drugs

P. Cohen, R. Swerdloff, Peter Y. Liu, 2015, Apoptosis.

Effects of 28 Days of Oral Dimethandrolone Undecanoate in Healthy Men: A Prototype Male Pill

Christina Wang, R. Swerdloff, W. Bremner, 2018, The Journal of clinical endocrinology and metabolism.

Androgen therapy in non-gonadal disease

David Handelsman, Peter Y. Liu, 1998 .

Serum Testosterone (T) Level Variability in T Gel-Treated Older Hypogonadal Men: Treatment Monitoring Implications.

T. Gill, M. Pahor, S. Bhasin, 2015, The Journal of clinical endocrinology and metabolism.

Dimethandrolone Undecanoate, a Novel Non-Aromatizable Androgen, Increases P1NP in Healthy Men over 28 days.

A. Hoofnagle, Christina Wang, Peter Y. Liu, 2020, The Journal of clinical endocrinology and metabolism.

Endogenous glucocorticoid signalling in osteoblasts is necessary to maintain normal bone structure in mice.

M. Seibel, C. Spies, R. Day, 2009, Bone.

Contraceptive efficacy of a depot progestin and androgen combination in men.

David Handelsman, Peter Y. Liu, M. Jimenez, 2003, The Journal of clinical endocrinology and metabolism.

Daily Oral Administration of the Novel Androgen 11β-MNTDC Markedly Suppresses Serum Gonadotropins In Healthy Men.

Christina Wang, R. Swerdloff, W. Bremner, 2020, The Journal of clinical endocrinology and metabolism.

Does ethnicity matter in male hormonal contraceptive efficacy?

R. Swerdloff, Peter Y. Liu, C. Wang, 2011, Asian journal of andrology.

Of mice, men, and hormones.

D. Tindall, V. Miller, Peter Y. Liu, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Sleep, testosterone and cortisol balance, and ageing men

Peter Y. Liu, Peter Y. Liu, Radha T Reddy, 2022, Reviews in endocrine & metabolic disorders.

Interleukin-2 drives cortisol secretion in an age-, dose-, and body composition-dependent way

P. Takahashi, J. Veldhuis, F. Roelfsema, 2020, Endocrine connections.

Older men exhibit reduced efficacy of and heightened potency downregulation by intravenous pulses of recombinant human LH: a study in 92 healthy men.

D. M. Keenan, P. Takahashi, J. Veldhuis, 2012, American journal of physiology. Endocrinology and metabolism.

Endogenous Diurnal Patterns of Adrenal and Gonadal Hormones During a 24-Hour Constant Routine After Simulated Shift Work

H. V. Van Dongen, M. Kelly, R. Auchus, 2022, Journal of the Endocrine Society.

The effects of humanin and its analogues on male germ cell apoptosis induced by chemotherapeutic drugs

P. Cohen, R. Swerdloff, Peter Y. Liu, 2015, Apoptosis.

Predicting pregnancy and spermatogenesis by survival analysis during gonadotrophin treatment of gonadotrophin-deficient infertile men.

V. Gebski, David Handelsman, Peter Y. Liu, 2002, Human reproduction.

Induction of spermatogenesis and fertility during gonadotropin treatment of gonadotropin-deficient infertile men: predictors of fertility outcome.

David Handelsman, M. Zacharin, Peter Y. Liu, 2009, The Journal of clinical endocrinology and metabolism.

A double-blind, placebo-controlled, randomized clinical trial of recombinant human chorionic gonadotropin on muscle strength and physical function and activity in older men with partial age-related androgen deficiency.

David Handelsman, Peter Y. Liu, S. Wishart, 2002, The Journal of clinical endocrinology and metabolism.

Hypothalamo-Pituitary Unit, Testis, and Male Accessory Organs

J. Veldhuis, Peter Y. Liu, 2019, Yen and Jaffe's Reproductive Endocrinology.

Chapter 13 – The Hypothalamo-Pituitary Unit, Testis, and Male Accessory Organs

J. Veldhuis, Peter Y. Liu, 2014 .

Rates of suppression and recovery of human sperm output in testosterone-based hormonal contraceptive regimens.

David Handelsman, Peter Y. Liu, L. P. Ly, 2005, Human reproduction.

Determinants of the rate and extent of spermatogenic suppression during hormonal male contraception: an integrated analysis.

Frederick C W Wu, David Handelsman, Christina Wang, 2008, The Journal of clinical endocrinology and metabolism.

Rate, extent, and modifiers of spermatogenic recovery after hormonal male contraception: an integrated analysis

David Handelsman, R. Swerdloff, Peter Y. Liu, 2006, The Lancet.

Recent methodological advances in male hormonal contraception.

R. Swerdloff, Peter Y. Liu, Christina Wang, 2010, Contraception.

10th Summit Meeting consensus: recommendations for regulatory approval for hormonal male contraception.

M. Mbizvo, S. Matlin, Frederick C W Wu, 2006, Journal of andrology.

Review article Recent methodological advances in male hormonal contraception

R. Swerdloff, Peter Y. Liu, Christina Wang, 2010 .

Androgens and cardiovascular disease.

David Handelsman, Peter Y. Liu, A. Death, 2003, Endocrine reviews.

An ensemble model of the male gonadal axis: illustrative application in aging men.

Ali Iranmanesh, D. M. Keenan, Johannes D Veldhuis, 2006, Endocrinology.

Do reproductive hormones modify insulin sensitivity and metabolism in older men? A randomized, placebo-controlled clinical trial of recombinant human chorionic gonadotropin.

David Handelsman, D. Celermajer, Peter Y. Liu, 2003, European journal of endocrinology.

Sensitivity and specificity of pulse detection using a new deconvolution method.

D. M. Keenan, J. Veldhuis, V. Padmanabhan, 2009, American journal of physiology. Endocrinology and metabolism.

Insights into the pathogenesis of XXY phenotype from comparison of the clinical syndrome with an experimental XXY mouse model.

R. Swerdloff, Peter Y. Liu, Y. Lue, 2010, Pediatric endocrinology reviews : PER.

Safety and Pharmacokinetics of Single-Dose Novel Oral Androgen 11&bgr;-Methyl-19-Nortestosterone-17&bgr;-Dodecylcarbonate in Men

Christina Wang, R. Swerdloff, W. Bremner, 2018, The Journal of clinical endocrinology and metabolism.

Acceptability of the oral hormonal male contraceptive prototype, 11β-Methyl-19-nortestosterone dodecylcarbonate (11β-MNTDC), in a 28-day placebo-controlled trial.

Christina Wang, R. Swerdloff, J. Amory, 2021, Contraception.

Dynamic testosterone responses to near-physiological LH pulses are determined by the time pattern of prior intravenous LH infusion.

D. M. Keenan, P. Takahashi, J. Veldhuis, 2012, American journal of physiology. Endocrinology and metabolism.

Klinefelter's syndrome--a microcosm of male reproductive health.

David Handelsman, Peter Y. Liu, 2006, The Journal of clinical endocrinology and metabolism.

Testosterone and Disordered Sleep

Peter Y. Liu, Peter Y. Liu, B. Chavoshan, 2021, Controversies in Testosterone Deficiency.

A Clinical Perspective of Sleep and Andrological Health: Assessment, Treatment Considerations and Future Research.

Peter Y. Liu, Peter Y. Liu, 2019, The Journal of clinical endocrinology and metabolism.

J. Eisman, J. Center, Tuan V. Nguyen, 2007, The Journal of clinical endocrinology and metabolism.

Chapter 16 – Sex Steroids and Skeletal Health in Men

M. Seibel, David Handelsman, Peter Y. Liu, 2006 .

Testosterone's short-term positive effect on luteinizing-hormone secretory-burst mass and its negative effect on secretory-burst frequency are attenuated in middle-aged men.

D. M. Keenan, P. Takahashi, J. Veldhuis, 2009, The Journal of clinical endocrinology and metabolism.

Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men.

D. M. Keenan, P. Takahashi, J. Veldhuis, 2010, American journal of physiology. Endocrinology and metabolism.

Randomized cross‐over clinical trial of injectable vs. implantable depot testosterone for maintenance of testosterone replacement therapy in androgen deficient men

David Handelsman, Peter Y. Liu, A. Conway, 2009, Clinical endocrinology.

Prospective Study of Effect of Androgens on Serum Inflammatory Markers in Men

David Handelsman, D. Celermajer, M. Ng, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Kinetics of removal of intravenous testosterone pulses in normal men.

D. M. Keenan, P. Takahashi, J. Veldhuis, 2010, European journal of endocrinology.

Continuous positive airway pressure increases pulsatile growth hormone secretion and circulating insulin-like growth factor-1 in a time-dependent manner in men with obstructive sleep apnea: a randomized sham-controlled study.

D. M. Keenan, R. Baxter, J. Veldhuis, 2014, Sleep.

Hypogonadism in Men With Chronic Renal Failure

David Handelsman, Peter Y. Liu, 2004 .

Joint synchrony of reciprocal hormonal signaling in human paradigms of both ACTH excess and cortisol depletion.

Steven M. Pincus, D. M. Keenan, J. Veldhuis, 2005, American journal of physiology. Endocrinology and metabolism.

Acceptability of oral dimethandrolone undecanoate in a 28-day placebo-controlled trial of a hormonal male contraceptive prototype.

Christina Wang, R. Swerdloff, W. Bremner, 2020, Contraception.

Analysis of bidirectional pattern synchrony of concentration-secretion pairs: implementation in the human testicular and adrenal axes.

Ferdinand Roelfsema, Steven M. Pincus, D. M. Keenan, 2005, American journal of physiology. Regulatory, integrative and comparative physiology.

Relative testosterone deficiency in older men: clinical definition and presentation.

R. Swerdloff, Peter Y. Liu, Christina Wang, 2005, Endocrinology and metabolism clinics of North America.

Androgen Therapy for Hypogonadism in Men with Chronic Illnesses

Peter Y. Liu, Peter Y. Liu, Wenyi Zhang, 2017 .

Implications of sleep restriction and recovery on metabolic outcomes.

S. Banks, Roo Killick, Peter Y. Liu, 2012, The Journal of clinical endocrinology and metabolism.

Endocrine regulation of bone turnover in men

M. Seibel, David Handelsman, Peter Y. Liu, 2005, Clinical endocrinology.

Clamping Cortisol and Testosterone Mitigates the Development of Insulin Resistance during Sleep Restriction in Men.

A. Iranmanesh, H. V. Van Dongen, J. Veldhuis, 2021, The Journal of clinical endocrinology and metabolism.

Age-specific changes in the regulation of LH-dependent testosterone secretion: assessing responsiveness to varying endogenous gonadotropin output in normal men.

A. Iranmanesh, P. Takahashi, J. Veldhuis, 2005, American journal of physiology. Regulatory, integrative and comparative physiology.

unmasks strong diurnal variations in the regularity of LH secretion A noninvasive measure of negative-feedback strength, approximate entropy,

Steven M. Pincus, D. M. Keenan, A. Porta, 2008 .

Mechanisms of hypoandrogenemia in healthy aging men.

D. M. Keenan, A. Iranmanesh, J. Veldhuis, 2005, Endocrinology and metabolism clinics of North America.

Initiating Dialogue in Community-Partnered Participatory Research to Address Obesity in South Los Angeles

Aziza Lucas-Wright, Peter Y. Liu, R. Bross, 2018, Journal of health care for the poor and underserved.

Oscillations in joint synchrony of reproductive hormones in healthy men.

Steven M. Pincus, D. M. Keenan, Johannes D Veldhuis, 2011, American journal of physiology. Endocrinology and metabolism.

Mouse model for men with klinefelter syndrome: a multifaceted fit for a complex disorder

R. Swerdloff, Peter Y. Liu, Y. Lue, 2011, Acta paediatrica.

Design of an International Male Contraceptive Efficacy Trial Using a Self-Administered Daily Transdermal Gel Containing Testosterone and Segesterone Acetate (Nestorone®).

R. Swerdloff, W. Bremner, J. Amory, 2023, Contraception.

Age and time-of-day differences in the hypothalamo-pituitary-testicular, and adrenal, response to total overnight sleep deprivation.

A. Iranmanesh, P. Takahashi, J. Veldhuis, 2020, Sleep.

Sensitivity and specificity of pulse detection using a new deconvolution method.

D. M. Keenan, J. Veldhuis, V. Padmanabhan, 2009, American Journal of Physiology. Endocrinology and Metabolism.

A noninvasive measure of negative-feedback strength, approximate entropy, unmasks strong diurnal variations in the regularity of LH secretion.

Steven M. Pincus, D. M. Keenan, A. Iranmanesh, 2007, American journal of physiology. Endocrinology and metabolism.