F. Miedema

P. Reiss, M. D. de Jong, S. Danner, 1997, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

Induction of a primary human cytotoxic T‐lymphocyte response against a novel conserved epitope in a functional sequence of HIV‐1 reverse transcriptase

S. H. van der Burg, C. Melief, C. V. D. van de Velde, 1995, AIDS.

Low T cell reactivity to combined CD3 plus CD28 stimulation is predictive for progression to AIDS: correlation with decreased CD28 expression

N. Pakker, R. Coutinho, P. Schellekens, 1996, Clinical and experimental immunology.

Rapid disease progression in human immunodeficiency virus type 1-infected individuals with adverse reactions to trimethoprim-sulfamethoxazole prophylaxis.

I. Keet, P. Veugelers, J. Veenstra, 1997, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Lack of T cell dysfunction and programmed cell death in human immunodeficiency virus type 1-infected chimpanzees correlates with absence of monocytotropic variants.

H. Schuitemaker, J. Heeney, N. Kootstra, 1993, The Journal of infectious diseases.

ASSOCIATION BETWEEN BIOLOGICAL PROPERTIES OF HUMAN IMMUNODEFICIENCY VIRUS VARIANTS AND RISK FOR AIDS AND AIDS MORTALITY

J. Goudsmit, F. Wolf, R. Coutinho, 1989, The Lancet.

T-cell progenitor function during progressive human immunodeficiency virus-1 infection and after antiretroviral therapy.

P. Reiss, F. Wit, S. Repping, 2000, Blood.

Biphasic rate of CD4+ cell count decline during progression to AIDS correlates with HIV‐1 phenotype

F. de Wolf, R. Coutinho, P. Schellekens, 1992, AIDS.

The predictive value of T cell function in vitro and pre-AIDS zidovudine use for survival after AIDS diagnosis in a cohort of homosexual men in Amsterdam.

J. Veenstra, M. Roos, F. Miedema, 1995, The Journal of infectious diseases.

Plasma levels of viro-immunological markers in HIV-infected and non-infected Ethiopians: correlation with cell surface activation markers.

T. F. Rinke de Wit, D. Hamann, T. Messele, 2001, Clinical immunology.

Predictors for non- and slow progression in human immunodeficiency virus (HIV) type 1 infection: low viral RNA copy numbers in serum and maintenance of high HIV-1 p24-specific but not V3-specific antibody levels.

F. de Wolf, F. Wolf, A. V. van Wijk, 1995, The Journal of infectious diseases.

No detrimental immunological effects of mycophenolate mofetil and HAART in treatment-naive acute and chronic HIV-1-infected patients

H. Schuitemaker, J. Prins, N. Vrisekoop, 2007 .

Reconstitution of naive T cells during antiretroviral treatment of HIV-infected adults is dependent on age

C. Boucher, R. D. de Boer, M. Roos, 2002, AIDS.

T cell expansions in lymph nodes and peripheral blood in HIV-1-infected individuals: effect of antiretroviral therapy

S. Kostense, P. Reiss, S. Danner, 2001, AIDS.

IL-10 and HIV-1 Replication

H. Schuitemaker, N. Kootstra, F. Miedema, 1995 .

Interference ofInterleukin-10 withHuman Immunodeficiency VirusType1Replication inPrimary Monocyte- Derived Macrophages

H. Schuitemaker, F. Miedema, 1994 .

Early replication steps but not cell type-specific signalling of the viral long terminal repeat determine HIV-1 monocytotropism.

H. Schuitemaker, N. Kootstra, R. Fouchier, 1993, AIDS research and human retroviruses.

Differential tropism of clinical HIV-1 isolates for primary monocytes and promonocytic cell lines.

H. Schuitemaker, N. Kootstra, F. Miedema, 1992, AIDS research and human retroviruses.

Correspondence

W., F. Miedema, Karen, 1905, Biological Psychiatry.

Toll-like receptor 7-adapter complex modulates interferon-α production in HIV-stimulated plasmacytoid dendritic cells

S. Migueles, M. Connors, J. Lifson, 2019, PloS one.

No evidence that vaccination with a polysaccharide pneumococcal vaccine protects drug users against all-cause pneumonia.

B. H. Benthem, M. Langendam, R. Coutinho, 2001, AIDS.

High prevalence of Epstein-Barr virus type 2 among homosexual men is caused by sexual transmission.

M. Kersten, D. Baarle, D. van Baarle, 2000, The Journal of infectious diseases.

The HIV RNA setpoint theory revisited

Ben Berkhout, Ronald B Geskus, Laurence Meyer, 2007, Retrovirology.

Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission.

Kees, H. Schuitemaker, N. Kootstra, 1994, The Journal of clinical investigation.

Viral phenotype and immune response in primary human immunodeficiency virus type 1 infection.

M. Roos, R. Coutinho, J. Lange, 1992, The Journal of infectious diseases.

Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolates

Lange, J. Goudsmit, F. de Wolf, 1989, Journal of virology.

Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule

H. Schuitemaker, N. Kootstra, R. Fouchier, 1992, Journal of virology.

Durable HIV-1 Suppression with Indinavir after Failing Lamivudine-Containing Double Nucleoside Therapy: A Randomized Controlled Trial

P. Portegies, N. Foudraine, G. Weverling, 2001, Antiviral therapy.

Highly active antiretroviral therapy with or without mycophenolate mofetil in treatment-naive HIV-1 patients

H. Schuitemaker, F. van Leth, M. Cornelissen, 2004, AIDS.

AIDS Pathogenesis

H. Schuitemaker, F. Miedema, 2000, Immunology and Medicine Series.

Intravenous immunoglobulin (IVIG) treatment for modulation of immune activation in human immunodeficiency virus type 1 infected therapy-naive individuals.

E. Bunnik, H. Schuitemaker, C. Hack, 2007, AIDS research and human retroviruses.

The Dominant Source of CD4+ and CD8+ T‐Cell Activation in HIV Infection Is Antigenic Stimulation

C. Boucher, R. D. de Boer, S. Otto, 2000, Journal of acquired immune deficiency syndromes.

Immunopathology as a result of highly active antiretroviral therapy in HIV-1-infected patients.

P. Reiss, N. Foudraine, M. Klein, 1999, AIDS.

Functional T cell reconstitution and human immunodeficiency virus-1-specific cell-mediated immunity during highly active antiretroviral therapy.

N. Foudraine, S. Danner, M. Klein, 1999, The Journal of infectious diseases.

Detection and subtyping of HIV-1 isolates with a panel of characterized monoclonal antibodies to HIV p24gag.

G. Groen, R. Gruters, F. Miedema, 1989, Virology.

Low T‐cell responses to CD3 plus CD28 monoclonal antibodies are predictive of development of AIDS

M. Prins, F. de Wolf, M. Bakker, 1998, AIDS.

Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population

H. Schuitemaker, N. Kootstra, J. Lange, 1992, Journal of virology.

Differential syncytium-inducing capacity of human immunodeficiency virus isolates: frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex

Huisman, F. Miedema, R. Gruters, 1988, Journal of virology.

Prognostic Value of HIV-1 Syncytium-Inducing Phenotype for Rate of CD4+ Cell Depletion and Progression to AIDS

I. Keet, M. Roos, R. Coutinho, 1993, Annals of Internal Medicine.

Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture

H. Schuitemaker, N. Kootstra, F. de Wolf, 1991, Journal of virology.

Association between CCR5 Genotype and the Clinical Course of HIV-1 Infection

H. Schuitemaker, I. Keet, M. Prins, 1997, Annals of Internal Medicine.

Use of Immunological and Viral Parameters to Predict Progression of HIV Infection During Natural Course and Antiretroviral Treatment

H. Schuitemaker, F. Miedema, M. Koot, 1997, BioDrugs.

Thermal Inactivation of Human Immunodeficiency Virus in Lyophilised Blood Products Evaluated by ID50 Titrations

F. Miedema, H. Huisman, J. Over, 1986, Vox sanguinis.

Biological Phenotype ofHumanImmunodeficiency VirusType1 Clones atDifferent Stages ofInfection: Progression ofDisease IsAssociated with a Shift fromMonocytotropic to T-Cell-Tropic VirusPopulations

H. Schuitemaker, N. Kootstra, J. Lange, 1992 .

OA06-05. Adaptation of HIV-1 to the human immune system at the population level is driven by protective HLA-B alleles

B. Berkhout, H. Schuitemaker, D. van Baarle, 2009, Retrovirology.

Cytotoxic T lymphocyte responses in HIV-1-infected long-term nonprogressors: lessons for vaccine design

H. Schuitemaker, M. Navis, F. Miedema, 2008 .

Surrogate Markers for Disease Progression in Treated HIV Infection

A. Ghani, C. Donnelly, N. Ferguson, 2001, Journal of acquired immune deficiency syndromes.

Rapid CD4+ T-cell turnover in HIV-1 infection: a paradigm revisited.

H. Schuitemaker, K. Wolthers, F. Miedema, 1998, Immunology today.

AIDS prognosis based on HIV‐1 RNA, CD4+ T‐cell count and function: markers with reciprocal predictive value over time after seroconversion

I Spijkerman, C. Kuiken, F. de Wolf, 1997, AIDS.

Early and late HIV‐1 RNA level and its association with other markers and disease progression in long‐term AIDS‐free homosexual men

M. Prins, P. Veugelers, F. de Wolf, 1997, AIDS.

Gag-specific immune responses after immunization with p17/p24:Ty virus-like particles in HIV type 1-seropositive individuals.

J. Veenstra, F. de Wolf, M. Klein, 1997, AIDS research and human retroviruses.

Frequent injecting impairs lymphocyte reactivity in HIV-positive and HIV-negative drug users.

M. Roos, R. Coutinho, P. Schellekens, 1991, AIDS.

Human immunodeficiency virus infection studied in CD4-expressing human-murine T-cell hybrids.

J. V. van Dongen, R. Weiss, P. Clapham, 1989, Virology.

BLOOD DONATIONS REACTIVE FOR HIV IN WESTERN BLOT, BUT NON-INFECTIVE IN CULTURE AND RECIPIENTS OF BLOOD

H. Reesink, F. Miedema, T. Tersmette, 1986, The Lancet.

CTL escape and increased viremia irrespective of HIV-specific CD4+ T-helper responses in two HIV-infected individuals.

Jaap Goudsmit, Hanneke Schuitemaker, Georgios Pollakis, 2006, Virology.

HIV-1 viral rebound dynamics after a single treatment interruption depends on time of initiation of highly active antiretroviral therapy

H. Schuitemaker, S. Jurriaans, J. Prins, 2008, AIDS.

Natural controlled HIV infection: preserved HIV-specific immunity despite undetectable replication competent virus.

H. Schuitemaker, A. Duits, D. van Baarle, 2005, Virology.

Lymphoproliferative response to HIV type 1 p24 in long-term survivors of HIV type 1 infection is predictive of persistent AIDS-free infection.

I. Keet, J. Goudsmit, M. Roos, 1999, AIDS research and human retroviruses.

Antigen-specific T-lymphocyte proliferative responses during highly active antiretroviral therapy (HAART) of HIV-1 infection.

S. Danner, M. Klein, N. Pakker, 1999, Immunology Letters.

UvA-DARE (Digital Academic Repository) Functional T cell reconstruction and human immunodeficiency virus-1-specific cell-mediated immunity during highly active antiretroviral therapy

N. Foudraine, S. Danner, M. Klein, 1999 .

T cell function in vitro is an independent progression marker for AIDS in human immunodeficiency virus-infected asymptomatic subjects.

M. Roos, R. Coutinho, P. Schellekens, 1995, The Journal of infectious diseases.

New evidence to reconcile in vitro and epidemiologic data on the possible role of heroin on CD4+ decline among HIV-infected injecting drug users.

D. Vlahov, R. Coutinho, E. V. van Ameijden, 1999, Drug and alcohol dependence.

Immunological and virological markers in individuals progressing from seroconversion to AIDS.

R. V. van Lier, F. de Wolf, F. Wolf, 1991, AIDS.

Normalization of the CD4 T cell receptor repertoire after evolution of syncytium-inducing HIV-1 variants.

H. Schuitemaker, S. Kostense, F. Miedema, 2000, AIDS.

Diversity of the T‐cell receptor BV repertoire in HIV‐1‐infected patients reflects the biphasic CD4+ T‐cell repopulation kinetics during highly active antiretroviral therapy

S. Kostense, S. Danner, J. Teale, 1998, AIDS.

Immune restoration does not invariably occur following long-term HIV-1 suppression during antiretroviral therapy. INCAS Study Group.

J. Montaner, P. Reiss, F. Wit, 1999, AIDS.

AIDS pathogenesis: a dynamic interaction between HIV and the immune system.

R. V. van Lier, F. Miedema, F Miedema, 1990, Immunology today.

Carrier rate of zidovudine-resistant HIV-1: the impact of failing therapy on transmission of resistant strains

M. Boerlijst, L. van der Hoek, G. Weverling, 2001, AIDS.

Viro‐immunological studies in acute HIV‐1 infection

H. Schuitemaker, N. Kootstra, F. Claessen, 1994, AIDS.

Changes in the composition of circulating CD8+ T cell subsets during acute epstein-barr and human immunodeficiency virus infections in humans.

D. Baarle, F. Miedema, R. V. van Lier, 2000, The Journal of infectious diseases.

OKT3 and IL-2 Treatment for Purging of the Latent HIV-1 Reservoir in Vivo Results in Selective Long-Lasting CD4+ T Cell Depletion

H. Schuitemaker, C. Fox, A. Eerenberg, 2001, Journal of Clinical Immunology.

Lymphocyte subsets, apoptosis, and cytokines in patients with chronic fatigue syndrome.

G. Bleijenberg, J. V. D. van der Meer, J. van der Ven-Jongekrijg, 1996, The Journal of infectious diseases.

Induction of monocyte proliferation and HIV expression by IL-3 does not interfere with anti-viral activity of zidovudine.

H. Schuitemaker, N. Kootstra, M. V. van Oers, 1990, Blood.

Standardisation and quality assurance of lymphocyte proliferation assays for use in the assessment of immune function. European Concerted Action on Immunological and Virological Markers of HIV Disease Progression.

G. Raab, M. Bofill, N. Pakker, 1999, Journal of immunological methods.

Restored humoral immune response to influenza vaccination in HIV‐infected adults treated with highly active antiretroviral therapy

A. Osterhaus, G. Rimmelzwaan, J. V. van Dissel, 1998, AIDS.

Immune reconstitution after 2 years of successful potent antiretroviral therapy in previously untreated human immunodeficiency virus type 1-infected adults.

N. Foudraine, J. Goudsmit, S. Danner, 1999, The Journal of infectious diseases.

Detection of Early Anti‐p24 HIV Responses in EIA‐ and Immunoblot‐Negative Individuals

J. Goudsmit, F. Miedema, P. Lelie, 1987, Vox sanguinis.

Confirmation of HIV seropositivity: Comparison of a novel radioimmunoprecipitation assay to immunoblotting and virus culture

F. Miedema, J. Lange, P. Lelie, 1988, Journal of medical virology.

Discordant responses during antiretroviral therapy: role of immune activation and T cell redistribution rather than true CD4 T cell loss.

F. Wit, M. Hazenberg, S. Otto, 2002, AIDS.

Phenotypical and functional analysis of T cells in periodontitis.

U. van der Velden, B. Loos, M. Roos, 2001, Journal of periodontal research.

Immunoglobulin subclasses of antibodies to human T-cell leukemia/lymphoma virus I-associated antigens in acquired immune deficiency syndrome and lymphadenopathy syndrome

J. Goudsmit, J. van der Noordaa, M. Roos, 1985, Journal of virology.

Large diurnal variation in CD4 cell count and T‐cell function among drug users: implications for clinical practice and epidemiological studies

R. Coutinho, M. Roos, G. H. Mientjes, 1992, AIDS.

HIV tropism and CD4+ T-cell depletion

John P. Moore, H. Schuitemaker, M. Feinberg, 2002, Nature Medicine.

Predictors of rapid progression to AIDS in HIV-1 seroconverters.

P. Krijnen, I. Keet, J. Goudsmit, 1993, AIDS.

Persistence of human immunodeficiency virus antigenemia in patients with the acquired immunodeficiency syndrome treated with a reverse transcriptase inhibitor, suramin. Ten-patient case-control study.

J. Goudsmit, S. Danner, J. Lange, 1988, Archives of internal medicine.

Immunologic and virologic markers determining progression to AIDS.

M. Roos, P. Schellekens, F. Miedema, 1995, Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology.

Analysis of CD8+ T lymphocyte-mediated nonlytic suppression of autologous and heterologous primary human immunodeficiency virus type 1 isolates.

H. Schuitemaker, N. Kootstra, F. Miedema, 1997, AIDS research and human retroviruses.

AIDS Pathogenesis: A Finite Immune Response to Blame?

F Miedema, M R Klein, F. Miedema, 1996, Science.

Immunological and virological markers determining progression to AIDS.

M. Roos, P. Schellekens, F. Miedema, 1994, Netherlands Journal of Medicine.

A brief history of HIV vaccine research: stepping back to the drawing board?

F. Miedema, 2008, AIDS.

T cell telomere length in HIV-1 infection: No evidence for increased CD4+ T cell turnover☆

Niels Schaft, Jaap Goudsmit, Linde Meyaard, 1997 .

Depletion of naive CD4 T cells by CXCR4-using HIV-1 variants occurs mainly through increased T-cell death and activation

Hanneke Schuitemaker, Rob J de Boer, H. Schuitemaker, 2003, AIDS.

T cell dynamics and protective immunity in HIV infection: a brief history of ideas.

F. Miedema, 2006, Current opinion in HIV and AIDS.

Syncytium-inducing HIV-1 variants replicate equally well in all types of T-helper cell clones.

R. Fouchier, F. Miedema, M. Brouwer, 1996, AIDS.

not interfere with anti-viral activity of zidovudine Induction of monocyte proliferation and HIV expression by IL-3 does

H. Schuitemaker, F. Miedema, M. Oers, 2011 .

Immunological abnormalities in human immunodeficiency virus (HIV)-infected asymptomatic homosexual men. HIV affects the immune system before CD4+ T helper cell depletion occurs.

Jaap, F. Miedema, A. J. Petit, 1988, The Journal of clinical investigation.

Longitudinal analysis of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte responses: a predominant gag-specific response is associated with nonprogressive infection.

H. Schuitemaker, F. Miedema, F. de Wolf, 1998, The Journal of infectious diseases.

Lower prevalence and incidence of HIV‐1 syncytium‐inducing phenotype among injecting drug users compared with homosexual men

I. Keet, M. Prins, R. Coutinho, 1995, AIDS.

Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics

H. Schuitemaker, R. Bende, F. Miedema, 1995, The Journal of experimental medicine.

Polymorphisms within the human tumor necrosis factor-alpha promoter region in human immunodeficiency virus type 1-seropositive persons.

B M Brinkman, I P Keet, F Miedema, 1997, The Journal of infectious diseases.

Sequence Variation intheThirdVariable DomainoftheHumanImmunodeficiency Virus Type1gpl20Molecule

H. Schuitemaker, F. Miedema, 1992 .