Marcus Weinguny

Random epigenetic modulation of CHO cells by repeated knockdown of DNA methyltransferases increases population diversity and enables sorting of cells with higher production capacities

N. Borth, A. Jonsson, Gerald Klanert, 2020, Biotechnology and bioengineering.

A cross-species whole genome siRNA screen in suspension-cultured Chinese hamster ovary cells identifies novel engineering targets

J. Shiloach, Vaibhav Jadhav, N. Borth, 2019, Scientific Reports.

Genome Variation, the Epigenome and Cellular Phenotypes

N. Borth, Gerald Klanert, Marcus Weinguny, 2019, Cell Culture Engineering.

Inclusion of maintenance energy improves the intracellular flux predictions of CHO

David E. Ruckerbauer, J. Zanghellini, I. Rocha, 2020, bioRxiv.

How to train your cell - Towards controlling phenotypes by harnessing the epigenome of Chinese hamster ovary production cell lines.

N. Borth, Gerald Klanert, Marcus Weinguny, 2022, Biotechnology advances.

Directed evolution approach to enhance efficiency and speed of outgrowth during single cell subcloning of Chinese Hamster Ovary cells

N. Borth, A. Jonsson, Gerald Klanert, 2020, Computational and structural biotechnology journal.

A cross-species whole genome siRNA screen in suspension-cultured Chinese hamster ovary cells identifies novel engineering targets

J. Shiloach, Vaibhav Jadhav, N. Borth, 2019, Scientific Reports.

Subcloning induces changes in the DNA‐methylation pattern of outgrowing Chinese hamster ovary cell colonies

W. Timp, N. Borth, Gerald Klanert, 2021, Biotechnology journal.

Systematic use of synthetic 5′-UTR RNA structures to tune protein translation improves yield and quality of complex proteins in mammalian cell factories

Johan Rockberg, N. Borth, D. Hatton, 2020, Nucleic acids research.