J. Lindberg

发表

Synthesis and comparative molecular field analysis (CoMFA) of symmetric and nonsymmetric cyclic sulfamide HIV-1 protease inhibitors.

J. Hulten, B. Samuelsson, A. Hallberg, 2001, Journal of medicinal chemistry.

Nocodazole Treatment of CV-1 Cells Enhances Nuclear/Perinuclear Accumulation of Lipid-DNA Complexes and Increases Gene Expression

J. D. Ropp, S. Hamm-Alvarez, J. Lindberg, 2001, Pharmaceutical Research.

In Vitro Resistance Profile of the Hepatitis C Virus NS3/4A Protease Inhibitor TMC435

L. Vrang, M. Cummings, Herman A de Kock, 2010, Antimicrobial Agents and Chemotherapy.

Induced-fit binding of the macrocyclic noncovalent inhibitor TMC435 to its HCV NS3/NS4A protease target.

Susanne Nyström, Maxwell D Cummings, Oliver Lenz, 2010, Angewandte Chemie.

Design and synthesis of potent hydroxyethylamine (HEA) BACE-1 inhibitors carrying prime side 4,5,6,7-tetrahydrobenzazole and 4,5,6,7-tetrahydropyridinoazole templates.

N. Borkakoti, Elizabeth Hamelink, L. Vrang, 2012, Bioorganic & medicinal chemistry letters.

Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant.

S. Sigurdsson, T. Unge, Hong Zhang, 2002, European journal of biochemistry.

Synthesis of potent BACE-1 inhibitors incorporating a hydroxyethylene isostere as central core.

N. Borkakoti, B. Samuelsson, A. Hallberg, 2010, European journal of medicinal chemistry.

Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues.

N. Borkakoti, B. Samuelsson, A. Hallberg, 2008, Bioorganic & medicinal chemistry.

Investigation of α-phenylnorstatine and α-benzylnorstatine as transition state isostere motifs in the search for new BACE-1 inhibitors.

Rikard Emanuelsson, Mats Larhed, B. Samuelsson, 2011, Bioorganic & medicinal chemistry.

Discovery of potent BACE-1 inhibitors containing a new hydroxyethylene (HE) scaffold: exploration of P1' alkoxy residues and an aminoethylene (AE) central core.

Anders Hallberg, L. Vrang, B. Samuelsson, 2010, Bioorganic & medicinal chemistry.

Structure-Assisted Design of Drugs Towards HIV-1 and Malaria Targets Applied on Reverse Transcriptase and Protease from HIV-1 and Plasmepsin II from Plasmodium falciparum

J. Lindberg, 2004 .

Highly potent macrocyclic BACE-1 inhibitors incorporating a hydroxyethylamine core: design, synthesis and X-ray crystal structures of enzyme inhibitor complexes.

Anders Dahlgren, Tatiana Agback, Per-Ola Johansson, 2012, Bioorganic & medicinal chemistry.

Design and synthesis of potent and selective BACE-1 inhibitors.

N. Borkakoti, L. Vrang, B. Samuelsson, 2010, Journal of medicinal chemistry.

Backbone Assignment of the MALT1 Paracaspase by Solution NMR

M. Mayzel, V. Orekhov, G. Stenberg, 2016, PloS one.

Structure and Function of Carbonic Anhydrases from Mycobacterium tuberculosis*

T. Bergfors, S. Mowbray, M. Högbom, 2005, Journal of Biological Chemistry.

Design and Synthesis of Novel Arylketo-containing P1-P3 Linked Macro-cyclic BACE-1 Inhibitors

B. Samuelsson, J. Lindberg, Veronica Sandgren, 2015, The open medicinal chemistry journal.

Symmetric fluoro-substituted diol-based HIV protease inhibitors. Ortho-fluorinated and meta-fluorinated P1/P1'-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacy.

Anders Hallberg, Guido Zuccarello, L. Vrang, 2004, European journal of biochemistry.

Design and synthesis of potent inhibitors of plasmepsin I and II: X-ray crystal structure of inhibitor in complex with plasmepsin II.

Elizabeth Hamelink, L. Vrang, B. Samuelsson, 2005, Journal of medicinal chemistry.

Synthesis of novel, potent, diol-based HIV-1 protease inhibitors via intermolecular pinacol homocoupling of (2S)-2-benzyloxymethyl-4-phenylbutanal.

B. Samuelsson, A. Hallberg, T. Unge, 2001, Journal of medicinal chemistry.

Design and synthesis of HIV-1 protease inhibitors. Novel tetrahydrofuran P2/P2'-groups interacting with Asp29/30 of the HIV-1 protease. Determination of binding from X-ray crystal structure of inhibitor protease complex.

B. Samuelsson, A. Hallberg, T. Unge, 2003 .

Synthesis of potent BACE-1 inhibitors incorporating a hydroxyethylene isostere as central core.

N. Borkakoti, B. Samuelsson, A. Hallberg, 2010, European journal of medicinal chemistry.

Highly potent macrocyclic BACE-1 inhibitors incorporating a hydroxyethylamine core: design, synthesis and X-ray crystal structures of enzyme inhibitor complexes.

B. Samuelsson, J. Lindberg, Veronica Sandgren, 2012, Bioorganic & medicinal chemistry.