B. Classon

发表

Synthesis and comparative molecular field analysis (CoMFA) of symmetric and nonsymmetric cyclic sulfamide HIV-1 protease inhibitors.

J. Hulten, B. Samuelsson, A. Hallberg, 2001, Journal of medicinal chemistry.

Solid-phase parallel synthesis and SAR of 4-amidofuran-3-one inhibitors of cathepsin S: effect of sulfonamides P3 substituents on potency and selectivity.

B. Samuelsson, A. Kallin, K. Benkestock, 2009, Bioorganic & medicinal chemistry.

The p-Methoxybenzyl Group as Protective Group of the Anomeric Centre. Selective Conversions of Hydroxy Groups into Bromo Groups in p-Methoxybenzyl 2-Deoxy-2-phthalimido-beta-D-glucopyranoside.

B. Samuelsson, B. Classon, S. Lawesson, 1984 .

Synthesis of Some Purine Carbocyclic Isosteres of 2′,3′-Dideoxy-3′-C-Hydroxymethyl Nucleosides as Potential Inhibitors of HIV

B. Samuelsson, B. Classon, S. C. Svensson, 1992 .

Design and fast synthesis of C-terminal duplicated potent C(2)-symmetric P1/P1'-modified HIV-1 protease inhibitors.

L. Vrang, B. Samuelsson, A. Hallberg, 1999, Journal of medicinal chemistry.

Synthesis of Mimics to Thymidine Triphosphate and 3′-Deoxy-3′-fluorothymidine Triphosphate

B. Samuelsson, B. Classon, I. Kvarnström, 1993 .

Synthesis of Some 2′,3′-Dideoxy-3′-C-Fluoromethyl and 3′-C-Azidomethyl Nucleosides

B. Samuelsson, B. Classon, I. Kvarnström, 1992 .

Characterization of a Set of HIV-1 Protease Inhibitors Using Binding Kinetics Data from a Biosensor-Based Screen

L. Vrang, B. Samuelsson, A. Hallberg, 2000, Journal of biomolecular screening.

HIV-1 protease inhibitors based on acyclic carbohydrates

B. Samuelsson, A. Hallberg, A. Karlén, 1998 .

Synthesis of enantiomerically pure cis and trans 2-aminocyclopentanecarboxylic acids. Use of proline replacements in potential HIV-protease inhibitors

D. Nöteberg, B. Samuelsson, A. Hallberg, 1997 .

A convenient synthesis of 1-(S)-[1′-(S)-(t-butyloxycarbonylamino)-2′-phenylethyl]oxirane. A useful building block in the synthesis of HIV protease inhibitors

B. Samuelsson, A. Hallberg, A. Karlén, 1997 .

Separation and quantitative determination of galactosamine and glucosamine at the nanogram level by sulphonyl chloride reaction and high-performance liquid chromatography

A. Hjerpe, B. Classon, B. Engfeldt, 1980 .

Synthesis of 2•,3•-Dideoxy-3•-C-hydroxymethylcytidine Phosphonomethyl Derivatives

B. Samuelsson, B. Classon, I. Kvarnström, 1998 .

Synthesis of 3′,4′-C-Bishydroxymethyl-2′,3′,4′-trideoxy-β-L-threo-pentopyranosyl Nucleosides as Potential Inhibitors of HIV

B. Samuelsson, B. Classon, S. C. Svensson, 1995 .

Novel Route to 4-Thiofuranosides. Synthesis of Methyl 4-Thio-α-D-Talofuranoside

B. Samuelsson, Zhengchun Liu, B. Classon, 1987 .

Synthesis and conformational analysis of pyrimidine nucleoside analogues with a rigid sugar moiety.

B. Samuelsson, B. Classon, T. Szabó, 1995, Bioorganic & medicinal chemistry.

Syntheses of the 2'-Acetate and Some Deoxy Analogues of p-Trifluoroacetamidophenyl 3-O-(3,6-Dideoxy-alpha-D-xylo-hexopyranosyl)-alpha-D-mannopyranoside.

B. Classon, T. Norberg, P. Garegg, 1984 .

Synthesis of 5-Iodo-1-(sodium 2-deoxy-beta-D-ribofuranosyluronate)uracil and 5-Iodo-1-(sodium beta-D-ribofuranosyluronate)uracil.

B. Samuelsson, B. Classon, 1985 .

Allylic alcohol transpositions in the carbohydrate moiety of pyrimidine nucleosides

B. Samuelsson, P. Ioannidis, B. Classon, 1993 .

Synthesis of 4-C-hydroxymethyl hexopyranosyl nucleosides as potential inhibitors of HIV

B. Samuelsson, B. Classon, M. Bjoersne, 1993 .

Synthesis of 2′,3′-dideoxycyclo-2′-pentenyl-3′-C-hydroxymethyl carbocyclic nucleoside analogues as potential anti-viral agents

B. Samuelsson, B. Classon, I. Kvarnström, 1995 .

Design and synthesis of new potent C2-symmetric HIV-1 protease inhibitors. Use of L-mannaric acid as a peptidomimetic scaffold.

B. Samuelsson, A. Hallberg, T. Unge, 1998, Journal of medicinal chemistry.

Synthesis of p-Trifluoroacetamidophenyl 3-O-[2-Acetamido-2-Deoxy-3-O-(α-L-Fucopyranosyl)-β-D-Glucopyranosyl]-β-D-Galactopyranoside and of p-Trifluoracetamidophenyl 3-O-[2-Acetamido-2-Deoxy-3-O(α-L-Fucopyranosyl)-4-O(β-D-Galactopyranosyl)-β-D-Glucopyranosyl]-β-D-Galactopyranoside, a Trisaccharide and

B. Classon, P. Garegg, A. Helland, 1989 .

Synthesis of Novel Isothionucleosides as Potential Antiviral Agents

B. Samuelsson, B. Classon, I. Kvarnström, 1998 .

Synthesis of 2',3'-didehydro-2',3'-dideoxy-3'-C-methyl substituted nucleosides

P. Ioannidis, B. Classon, I. Kvarnström, 1993 .

Allylic Alcohol Transpositions in the Carbohydrate Moiety of Pyrimidine Nucleosides.

P. Ioannidis, B. Classon, B. Samuelson, 1993 .

Cyclic HIV-1 protease inhibitors derived from mannitol: synthesis, inhibitory potencies, and computational predictions of binding affinities.

J. Åqvist, J. Hulten, B. Samuelsson, 1997, Journal of medicinal chemistry.

Synthesis of 2′,3′-dideoxy-3′,4′-dihydroxymethyl substituted pyrimidine nucleoside analogues

B. Samuelsson, B. Classon, I. Kvarnström, 1995 .

Synthesis of Some 2′,3′-Dideoxy-2′-C-Methyl-Substituted Nucleosides

B. Samuelsson, P. Ioannidis, B. Classon, 1992 .

Synthesis of an artificial antigen that corresponds to a disaccharide repeating unit of the capsular polysaccharide of Haemophilus influenzae type d. A facile synthesis of methyl 2-acetamido-2-deoxy-beta-D-mannopyranoside.

B. Classon, S. Oscarson, P. Garegg, 1992, Carbohydrate research.

Synthesis of 2',3'-dideoxy-3'-C-hydroxymethyl nucleosides having the L-configuration as potential inhibitors of HIV

B. Samuelsson, B. Classon, I. Kvarnström, 1992 .

Synthesis of Novel Fluoro Carbocyclic Purine Nucleoside Analogues

B. Samuelsson, B. Classon, J. Wachtmeister, 1997 .

Synthesis of Novel Fluoro Carbocyclic Purine Nucleoside Analogues.

B. Samuelsson, B. Classon, J. Wachtmeister, 1997 .

A FACILE PREPARATION OF 2′,3′-UNSATURATED NUCLEOSIDES AND HEXOPYRANOSIDES FROM ACETYLATED HALOHYDRINS BY REDUCTIVE ELIMINATION

B. Samuelsson, J. Depierre, B. Classon, 1982 .

Conversion of hydroxyl groups into bromo groups in carbohydrates with inversion of configuration

B. Samuelsson, B. Classon, P. Garegg, 1981 .

SYNTHESIS OF 2,6-DIDEOXY-6-THIO DERIVATIVES OF KDO

B. Samuelsson, Zhengchun Liu, B. Classon, 1991 .

Synthesis of Enantiomerically Pure Bis(hydroxymethyl)-Branched Cyclohexenyl and Cyclohexyl Purines as Potential Inhibitors of HIV.

B. Samuelsson, B. Classon, Bertil Samuelsson, 1996, The Journal of organic chemistry.

SYNTHESIS OF 4-SUBSTITUTED CARBOCYCLIC 2,3-DIDEOXY-3-C-HYDROXYMETHYL NUCLEOSIDE ANALOGUES AS POTENTIAL ANTI-VIRAL AGENTS

B. Samuelsson, B. Classon, J. Wachtmeister, 1999 .

Synthesis of 3-deoxy-6-thio-d-manno-2-octulosonic acid (“6-thio-KDO”)

B. Samuelsson, Zhengchun Liu, B. Classon, 1988 .

Synthesis of p-trifluoroacetamidophenyl beta-D-glucopyranoside 4-(D-ribit-5-yl phosphate) corresponding to the Haemophilus influenzae type A capsular antigen.

B. Classon, P. Garegg, I. Lindh, 1988, Carbohydrate research.

Synthesis of C-2 symmetric potential inhibitors of HIV-1 protease from D-mannitol

B. Samuelsson, A. Hallberg, A. Karlén, 1996 .

Synthesis of [4,5-Bis(hydroxymethyl)-1,3-oxathiolan-2-yl]nucleosides as Potential Inhibitors of HIV via Stereospecific Base-Induced Rearrangement of a 2,3-Epoxy Thioacetate(1).

B. Samuelsson, B. Classon, I. Kvarnström, 1996, The Journal of organic chemistry.

Symmetric fluoro-substituted diol-based HIV protease inhibitors. Ortho-fluorinated and meta-fluorinated P1/P1'-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacy.

Anders Hallberg, Guido Zuccarello, L. Vrang, 2004, European journal of biochemistry.

Optimization of P1-P3 groups in symmetric and asymmetric HIV-1 protease inhibitors.

Wesley Schaal, Anders Karlén, Magnus Björsne, 2003, European journal of biochemistry.

Discovery of novel, potent and bioavailable proline-urea based macrocyclic HCV NS3/4A protease inhibitors.

L. Vrang, B. Samuelsson, Lili Hu, 2008, Bioorganic & medicinal chemistry letters.

P1/P1' modified HIV protease inhibitors as tools in two new sensitive surface plasmon resonance biosensor screening assays.

J. Hulten, B. Samuelsson, A. Hallberg, 2001, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain

C. Edenius, E. Lindström, M. Malcangio, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Uronic acid analysis by high-performance liquid chromatography after methanolysis of glycosaminoglycans

A. Hjerpe, B. Classon, B. Engfeldt, 1982 .

Synthesis of novel, potent, diol-based HIV-1 protease inhibitors via intermolecular pinacol homocoupling of (2S)-2-benzyloxymethyl-4-phenylbutanal.

B. Samuelsson, A. Hallberg, T. Unge, 2001, Journal of medicinal chemistry.

Inhibitors of the C(2)-symmetric HIV-1 protease: nonsymmetric binding of a symmetric cyclic sulfamide with ketoxime groups in the P2/P2' side chains.

J. Hulten, B. Samuelsson, A. Hallberg, 1999, Journal of medicinal chemistry.

Specific interaction between HIV-1 proteinase and 5'-phosphate peptidomimetic derivatives of nucleoside analogues.

I. Ugi, J. Chattopadhyaya, B. Classon, 1995, Drug Design and Discovery.

Novel potent macrocyclic inhibitors of the hepatitis C virus NS3 protease: use of cyclopentane and cyclopentene P2-motifs.

Elizabeth Hamelink, L. Vrang, B. Samuelsson, 2007, Bioorganic & medicinal chemistry.

Design and synthesis of new potent C2-symmetric HIV-1 protease inhibitors. Use of L-mannaric acid as a peptidomimetic scaffold.

B. Samuelsson, A. Hallberg, T. Unge, 1998, Journal of medicinal chemistry.