S. Paliwal

发表

Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors.

Shuxia Zhao, Leigh Zawel, Stephen Fawell, 2013, Cancer discovery.

Isolation of circulating metabolites in drug discovery using high-performance liquid chromatography, and their identification by liquid chromatography coupled with tandem mass spectrometry and nuclear magnetic resonance spectroscopy

K. Cox, A. Nomeir, M. Bryant, 2002 .

Cyclic urea derivatives as potent NK1 selective antagonists.

J. Lachowicz, A. Nomeir, C. Morgan, 2005, Bioorganic & medicinal chemistry letters.

Cyclobutane derivatives as potent NK1 selective antagonists.

J. Lachowicz, C. Morgan, G. Varty, 2006, Bioorganic & medicinal chemistry letters.

Cyclic urea derivatives as potent NK1 selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions.

J. Lachowicz, A. Nomeir, C. Morgan, 2006, Bioorganic & medicinal chemistry letters.

Asymmetric synthesis of 4,4-disubstituted-2-imidazoli-dinones: potent NK1 antagonists.

A. McPhail, S. Paliwal, N. Shih, 2003, Organic letters.

Discovery of ZN-c3, a Highly Potent and Selective Wee1 Inhibitor Undergoing Evaluation in Clinical Trials for the Treatment of Cancer.

A. Samatar, Sunny Abraham, S. Paliwal, 2021, Journal of medicinal chemistry.

Structural basis of CX‐4945 binding to human protein kinase CK2

A. Ferguson, T. Fischmann, P. Sheth, 2011, FEBS letters.

Design and biological characterization of a series of dual mechanism ERK1/2 inhibitors with a Triazolopyridinone core

P. Tolias, M. Sabio, S. Paliwal, 2022, Chemical biology & drug design.

MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology.

K. Cox, P. Kirschmeier, R. Doll, 2018, ACS medicinal chemistry letters.

Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncology.

P. Kirschmeier, R. Doll, W. Windsor, 2018, Bioorganic & medicinal chemistry letters.

Disulfide bond assignments and secondary structure analysis of human and murine interleukin 10.

P. Mui, W. Windsor, Rumin Zhang, 1993, Biochemistry.

Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation.

D. Tulshian, T. Fischmann, C. Garlisi, 2015, ACS medicinal chemistry letters.

Preparation of oxime dual NK(1)/NK(2) antagonists with reduced NK(3) affinity.

Cheryl A. Grice, S. Paliwal, N. Shih, 2002, Bioorganic & medicinal chemistry letters.