Simon Peace

The developability of heteroaromatic and heteroaliphatic rings – do some have a better pedigree as potential drug molecules than others?

Stephen D. Pickett, Simon J. F. Macdonald, Christopher N. Luscombe, 2012 .

Increasing small molecule drug developability in sub-optimal chemical space

S. Pickett, T. Ritchie, S. Macdonald, 2013 .

The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis

M. Karsdal, C. Swanton, G. Bergamini, 2019, Nature Communications.

Discovery of Potent, Efficient, and Selective Inhibitors of Phosphoinositide 3-Kinase δ through a Deconstruction and Regrowth Approach.

M. Convery, P. Rowland, Simon Peace, 2018, Journal of medicinal chemistry.

Agents Acting on Prostanoid and Thromboxane Receptors

Simon Peace, A. Hall, M. Swarbrick, 2010 .

Pyridyl-2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists: synthesis, pharmacokinetics, and in vivo potency.

I. E. Smith, P. Woollard, J. Liddle, 2006, Journal of medicinal chemistry.

Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.

P. Rowland, C. Jamieson, Simon Peace, 2016, Journal of medicinal chemistry.

UV‐Induced 1,3,4‐Oxadiazole Formation from 5‐Substituted Tetrazoles and Carboxylic Acids in Flow

L. Green, C. Jamieson, Simon Peace, 2020, Chemistry.

The discovery of GSK221149A: a potent and selective oxytocin antagonist.

Michael J Allen, John Liddle, Fabrizio Nerozzi, 2008, Bioorganic & medicinal chemistry letters.