S. Bonar

发表

Discovery of PH-797804, a highly selective and potent inhibitor of p38 MAP kinase.

Dean M. Messing, G. Anderson, J. Monahan, 2011, Bioorganic & medicinal chemistry letters.

Selective inhibition of the p38α MAPK–MK2 axis inhibits inflammatory cues including inflammasome priming signals

J. Monahan, J. Hirsch, Y. Alippe, 2018, The Journal of experimental medicine.

Aminopyridinecarboxamide-based inhibitors: Structure-activity relationship.

R. Weier, F. Koszyk, J. Guzova, 2010, Bioorganic & medicinal chemistry.

A Selective IKK-2 Inhibitor Blocks NF-κB-dependent Gene Expression in Interleukin-1β-stimulated Synovial Fibroblasts*

M. Yao, R. Weier, M. Graneto, 2003, Journal of Biological Chemistry.

Wnt Signaling via Interactions with β-catenin

R. Civitelli, G. Mbalaviele, S. Bonar, 2013 .

Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with &bgr;-catenin

R. Civitelli, G. Mbalaviele, S. Bonar, 2013, Journal of Cell Science.

Epidermal growth factor precursor is present in a variety of human renal cyst fluids.

R. Clayman, D. Moskowitz, S. Bonar, 1995, The Journal of urology.

Novel Tight-Binding Inhibitory Factor-κB Kinase (IKK-2) Inhibitors Demonstrate Target-Specific Anti-Inflammatory Activities in Cellular Assays and following Oral and Local Delivery in an in Vivo Model of Airway Inflammation

J. F. Schindler, J. Guzova, S. Bonar, 2009, Journal of Pharmacology and Experimental Therapeutics.

A Novel, Highly Selective, Tight Binding IκB Kinase-2 (IKK-2) Inhibitor: A Tool to Correlate IKK-2 Activity to the Fate and Functions of the Components of the Nuclear Factor-κB Pathway in Arthritis-Relevant Cells and Animal Models

D. Thompson, J. F. Schindler, J. Guzova, 2009, Journal of Pharmacology and Experimental Therapeutics.

Novel Insights into the Cellular Mechanisms of the Anti-inflammatory Effects of NF-κB Essential Modulator Binding Domain Peptides

J. F. Schindler, J. Chrencik, J. Guzova, 2010, The Journal of Biological Chemistry.

A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts.

M. Yao, R. Weier, M. Graneto, 2003, The Journal of biological chemistry.

Constitutively Activated NLRP3 Inflammasome Causes Inflammation and Abnormal Skeletal Development in Mice

D. Kastner, R. Civitelli, James L. Mueller, 2012, PloS one.

Inhibition of IKK-2 by 2-[(aminocarbonyl)amino]-5-acetylenyl-3-thiophenecarboxamides.

R. Weier, J. Guzova, S. Bonar, 2005, Bioorganic & medicinal chemistry letters.

Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation

Y. Alippe, R. Civitelli, G. Mbalaviele, 2016, Cell Death and Disease.

NLRP3 mediates osteolysis through inflammation‐dependent and ‐independent mechanisms

R. Civitelli, G. Mbalaviele, Y. Abu-Amer, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Sequence Analysis of the Candida albicans ADE2 Gene and Physical Separation of the Two Functionally Distinct Domains of the Phosphoribosylaminoimidazole Carboxylase

S. Dotson, V. Davisson, S. Bonar, 1997, Yeast.

Aminopyridinecarboxamide-based inhaled IKK-2 inhibitors for asthma and COPD: Structure-activity relationship.

G. Poda, R. Kurumbail, S. Selness, 2011, Bioorganic & medicinal chemistry.

JAK inhibition with tofacitinib suppresses arthritic joint structural damage through decreased RANKL production.

Steven A. Bailey, M. Hegen, J. Guzova, 2012, Arthritis and rheumatism.

Design, synthesis and activity of a potent, selective series of N-aryl pyridinone inhibitors of p38 kinase.

R. Kurumbail, Dean M. Messing, J. F. Schindler, 2011, Bioorganic & medicinal chemistry letters.