M. Betz

发表

Water Makes the Difference: Rearrangement of Water Solvation Layer Triggers Non‐additivity of Functional Group Contributions in Protein–Ligand Binding

Gerhard Klebe, Adam Biela, Michael Betz, 2012, ChemMedChem.

Dissecting the hydrophobic effect on the molecular level: the role of water, enthalpy, and entropy in ligand binding to thermolysin.

Gerhard Klebe, Adam Biela, Michael Betz, 2013, Angewandte Chemie.

Active Site Mapping of an Aspartic Protease by Multiple Fragment Crystal Structures: Versatile Warheads To Address a Catalytic Dyad.

G. Klebe, A. Heine, M. Weiss, 2016, Journal of medicinal chemistry.

Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1

R. Huber, K. Brew, W. Bode, 1997, Nature.

Methyl, Ethyl, Propyl, Butyl: Futile But Not for Water, as the Correlation of Structure and Thermodynamic Signature Shows in a Congeneric Series of Thermolysin Inhibitors

Gerhard Klebe, Michael Betz, G. Klebe, 2014, ChemMedChem.

Antioxidant capacity of bilberry extract microencapsulated in whey protein hydrogels

U. Kulozik, E. Richling, K. Mäder, 2012 .

Microencapsulation of bioactive bilberry anthocyanins by means of whey protein gels

U. Kulozik, M. Betz, 2011 .

Launching spiking ligands into a protein-protein interface: a promising strategy to destabilize and break interface formation in a tRNA modifying enzyme.

Luzi J. Barandun, G. Klebe, F. Diederich, 2013, ACS chemical biology.

Preparation and comparative release characteristics of three anthocyanin encapsulation systems.

S. Leick, H. Rehage, U. Kulozik, 2012, Journal of agricultural and food chemistry.

The helping hand of collagenase-3 (MMP-13): 2.7 A crystal structure of its C-terminal haemopexin-like domain.

C. López-Otín, W. Bode, U. Gohlke, 1996, Journal of molecular biology.

Cycloadditionsreaktionen des tetrachlor-o-benzochinons mit fulvenen

T. Debaerdemaeker, M. Betz, W. Friedrichsen, 1976 .

Is the antioxidative effectiveness of a bilberry extract influenced by encapsulation?

S. Leick, H. Rehage, U. Kulozik, 2014, Journal of the science of food and agriculture.

Replacement of water molecules in a phosphate binding site by furanoside-appended lin-benzoguanine ligands of tRNA-guanine transglycosylase (TGT).

Luzi J. Barandun, G. Klebe, F. Diederich, 2015, Chemistry.

Swelling behaviour, charge and mesh size of thermal protein hydrogels as influenced by pH during gelation

U. Kulozik, M. Betz, Josef Hörmansperger, 2012 .

Reconstitution of the core complex (alpha beta)3APCLC8.9 of the phycobilisome from Mastigocladus laminosus using the Lc8.9 linker polypeptide overexpressed in Escherichia coli.

H. Zuber, W. Sidler, U. Rüegsegger, 1993, Biological chemistry Hoppe-Seyler.

Separation of naturally occurring high molecular weight metal complexes from seawater

M. Betz, 1979 .

Screening of A-Substitution in the System A0.68Sr0.3Fe0.8Co0.2O3 − δ for SOFC Cathodes

J. M. Serra, F. Tietz, W. Meulenberg, 2008 .

Thermodynamic signatures of fragment binding: Validation of direct versus displacement ITC titrations.

G. Klebe, A. Heine, M. Schäfer, 2015, Biochimica et biophysica acta.

Life Cycle Assessment (LCA) in Strategic Risk Management

P. Eyerer, M. Betz, H. Schoech, 2001 .

Development of new cyclic plasmin inhibitors with excellent potency and selectivity.

G. Klebe, T. Steinmetzer, Sebastian M. Saupe, 2013, Journal of medicinal chemistry.

Investigations on the simultaneous uptake and release of mercury by Dunaliella tertiolecta

M. Betz, 1977 .

(4+2)‐CYCLOADDITIONEN VON FULVENEN MIT O‐CHINONEN

M. Betz, W. Friedrichsen, R. Schmidt, 1974 .

Boosting Affinity by Correct Ligand Preorganization for the S2 Pocket of Thrombin: A Study by Isothermal Titration Calorimetry, Molecular Dynamics, and High‐Resolution Crystal Structures

G. Klebe, A. Heine, M. Betz, 2016, ChemMedChem.

Diels-Alder-Reaktionen von o-Benzochinonen mit Fulvenen

M. Betz, H. Jürgens, W. Friedrichsen, 1978 .

Preparation of novel whey protein-based aerogels as drug carriers for life science applications

U. Kulozik, I. Smirnova, C. García-González, 2012 .

Effect of microformulation on the bioactivity of an anthocyanin-rich bilberry pomace extract ( Vaccinium myrtillus L.) in vitro.

S. Leick, H. Rehage, U. Kulozik, 2013, Journal of agricultural and food chemistry.

Whey protein gels for the entrapment of bioactive anthocyanins from bilberry extract

U. Kulozik, M. Betz, 2011 .

Crystal structure of yellow meal worm alpha-amylase at 1.64 A resolution.

R. Huber, R. Glockshuber, G. Wiegand, 1998, Journal of molecular biology.

1.8-A crystal structure of the catalytic domain of human neutrophil collagenase (matrix metalloproteinase-8) complexed with a peptidomimetic hydroxamate primed-side inhibitor with a distinct selectivity profile.

W. Bode, F. Gomis-Rüth, P. Huxley, 1997, European journal of biochemistry.

Rational Design of Thermodynamic and Kinetic Binding Profiles by Optimizing Surface Water Networks Coating Protein-Bound Ligands.

Gerhard Klebe, Stefan G Krimmer, Michael Betz, 2016, Journal of medicinal chemistry.

Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design.

G. Klebe, A. Mitschler, A. Podjarny, 2014, Acta crystallographica. Section D, Biological crystallography.

Supported Oxygen Transport Membranes for Oxyfuel Power Plants

D. Stöver, S. Baumann, W. Meulenberg, 2010 .

Beyond affinity: enthalpy-entropy factorization unravels complexity of a flat structure-activity relationship for inhibition of a tRNA-modifying enzyme.

Luzi J. Barandun, G. Klebe, F. Diederich, 2014, Journal of medicinal chemistry.

Expression, Purification, Characterization, and X-Ray Analysis of Selenomethionine 215 Variant of Leukocyte Collagenase

W. Bode, N. Budisa, H. Tschesche, 1997, Journal of protein chemistry.

Using GaBi 3 to perform life cycle assessment and life cycle engineering

Michael Betz, M. Faltenbacher, Martin Baitz, 2001 .

A Simple Way to Eliminate Oils from Water

Michael Betz, M. Betz, 2002 .

Influence of sintering conditions on microstructure and oxygen permeation of Ba0.5Sr0.5Co0.8Fe0.2O3-δ (BSCF) oxygen transport membranes

D. Stöver, E. Pfaff, M. Zwick, 2010 .

Impact of Surface Water Layers on Protein-Ligand Binding: How Well Are Experimental Data Reproduced by Molecular Dynamics Simulations in a Thermolysin Test Case?

Gerhard Klebe, Michael Betz, Tobias Wulsdorf, 2016, J. Chem. Inf. Model..

Fractionation of liquid egg yolk : Influence of chemical and structural characteristics of egg yolk granular and plasma fraction on the continuous centrifugal separation process

U. Kulozik, M. Betz, S. Thomas, 2011 .

Fragment Binding Can Be Either More Enthalpy-Driven or Entropy-Driven: Crystal Structures and Residual Hydration Patterns Suggest Why.

Gerhard Klebe, Michael Betz, G. Klebe, 2015, Journal of medicinal chemistry.

An Approach for Assessing the Benefits of IT Investments in Global supply Chains

Stefan Henningsson, Michaela Betz, S. Henningsson, 2016, ECIS.

Can qualitatively similar temperature-histories be obtained in different pilot HP units?

T. Grauwet, I. V. D. Plancken, G. Moates, 2011 .

An Approach for Assessing the Benefits of IT Investments in Global supply Chains

S. Henningsson, M. Betz, 2016, European Conference on Information Systems.