J. Paulsen

发表

Scoring Ensembles of Docked Protein: Ligand Interactions for Virtual Lead Optimization

Amy C. Anderson, Janet L. Paulsen, A. Anderson, 2009, J. Chem. Inf. Model..

Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond.

C. Schiffer, E. Nalivaika, Akbar Ali, 2021, Chemical reviews.

Alpha-S-GalCer: synthesis and evaluation for iNKT cell stimulation.

A. Anderson, J. Paulsen, A. Howell, 2008, Bioorganic & medicinal chemistry letters.

Interdependence of Inhibitor Recognition in HIV-1 Protease

C. Schiffer, Debra A. Ragland, J. Paulsen, 2017, Journal of chemical theory and computation.

Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species.

A. Anderson, D. Wright, J. Paulsen, 2013, Bioorganic & medicinal chemistry letters.

CRISPR-Cas9–mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy

Michael R. Green, C. Schiffer, D. Bolon, 2017, Proceedings of the National Academy of Sciences.

Drug Resistance Mutations Alter Dynamics of Inhibitor-Bound HIV-1 Protease

C. Schiffer, Yufeng Cai, R. Ishima, 2014, Journal of chemical theory and computation.

Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata

N. Priestley, J. Alverson, A. Anderson, 2014, Journal of medicinal chemistry.

Citrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα

C. Schiffer, P. Thompson, I. Ho, 2017, Science Immunology.

Crystal Structures of Candida albicans Dihydrofolate Reductase Bound to Propargyl‐Linked Antifolates Reveal the Flexibility of Active Site Loop Residues Critical for Ligand Potency and Selectivity

A. Anderson, J. Paulsen, S. Bendel, 2011, Chemical biology & drug design.

In vitro biological activity and structural analysis of 2,4-diamino-5-(2'-arylpropargyl)pyrimidine inhibitors of Candida albicans.

N. Priestley, A. Anderson, D. Wright, 2009, Bioorganic & medicinal chemistry.

2,4-Diamino-5-(2'-arylpropargyl)pyrimidine derivatives as new nonclassical antifolates for human dihydrofolate reductase inhibition.

A. Anderson, J. Paulsen, Oztekin Algul, 2011, Journal of molecular graphics & modelling.

Evaluation of Free Energy Calculations for the Prioritization of Macrocycle Synthesis

Lingle Wang, Daniel J. Sindhikara, Janet L Paulsen, 2020, J. Chem. Inf. Model..

Hydration Structure and Dynamics of Inhibitor-Bound HIV-1 Protease.

C. Schiffer, Y. Muller, J. Paulsen, 2018, Journal of chemical theory and computation.

Probing Structural Changes among Analogous Inhibitor-Bound Forms of HIV-1 Protease and a Drug-Resistant Mutant in Solution by NMR

R. Ishima, Nese Kurt-Yilmaz, J. Paulsen, 2018 .

Probing Structural Changes among Analogous Inhibitor-Bound Forms of HIV-1 Protease and a Drug-Resistant Mutant in Solution by Nuclear Magnetic Resonance.

C. Schiffer, R. Ishima, Nese Kurt-Yilmaz, 2018, Biochemistry.

In vitro biological activity and structural analysis of 2,4-diamino-5-(2'-arylpropargyl)pyrimidine inhibitors of Candida albicans.

N. Priestley, A. Anderson, D. Wright, 2009, Bioorganic & medicinal chemistry.

Phenotypic and molecular analysis of mes-3, a maternal-effect gene required for proliferation and viability of the germ line in C. elegans.

S. Strome, E. Capowski, J. Paulsen, 1995, Genetics.