J. Simmer

发表

MMP-20 is predominately a tooth-specific enzyme with a deep catalytic pocket that hydrolyzes type V collagen.

L. Cantley, B. Turk, A. Klingenhoff, 2006, Biochemistry.

WDR72 Mutations Associated with Amelogenesis Imperfecta and Acidosis

M. Jacquemont, F. Seymen, J. Simmer, 2019, Journal of dental research.

Meeting report: a hard look at the state of enamel research

O. Klein, A. Kulkarni, T. Diekwisch, 2017, International Journal of Oral Science.

Kallikrein-Related Peptidase 4

J. Simmer, 2013 .

Expression of kallikrein-related peptidase 4 in dental and non-dental tissues.

J. Simmer, Charles E. Smith, A. S. Richardson, 2011, European journal of oral sciences.

Hypomaturation Enamel Defects in Klk4 Knockout/LacZ Knockin Mice*

Y. Yamakoshi, J. Simmer, Yuanyuan Hu, 2009, The Journal of Biological Chemistry.

Characteristics of the transverse 2D uniserial arrangement of rows of decussating enamel rods in the inner enamel layer of mouse mandibular incisors

J. Simmer, Yuanyuan Hu, J. Hu, 2019, Journal of anatomy.

ENAM mutations and digenic inheritance

Jung‐Wook Kim, F. Seymen, J. Simmer, 2019, Molecular genetics & genomic medicine.

Analyses of oligodontia phenotypes and genetic etiologies

Jung‐Wook Kim, Feng Wang, Yiqun Wu, 2021, International journal of oral science.

Candidate gene sequencing reveals mutations causing hypoplastic amelogenesis imperfecta

Z. Lee, T. Shin, H. Hyun, 2018, Clinical Oral Investigations.

Novel KLK4 and MMP20 Mutations Discovered by Whole-exome Sequencing

F. Seymen, J. Simmer, J. D. Bartlett, 2013, Journal of dental research.

Craniofacial Disorders Affecting the Dentition: Genetic

P. Krebsbach, J. Simmer, Y. Chun, 2013 .

Regulation of Dental Enamel Shape and Hardness

Adam N. Rountrey, P. Papagerakis, J. Simmer, 2010, Journal of dental research.

FAM83H mutations in families with autosomal-dominant hypocalcified amelogenesis imperfecta.

Z. Lee, Jung‐Wook Kim, Joo-Cheol Park, 2008, American journal of human genetics.

Critical roles for WDR72 in calcium transport and matrix protein removal during enamel maturation

J. Simmer, S. Núñez, A. S. Richardson, 2015, Molecular genetics & genomic medicine.

Genetic Craniofacial Disorders Affecting the Dentition

P. Krebsbach, J. Simmer, Y. Chun, 2018, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism.

Endocytosis and Enamel Formation

J. Simmer, C. Pham, Yuanyuan Hu, 2017, Front. Physiol..

Characterization of kallikrein-related peptidase 4 glycosylations.

Y. Yamakoshi, J. Simmer, J. Hu, 2011, European journal of oral sciences.

STIM1 and SLC24A4 Are Critical for Enamel Maturation

F. Seymen, J. Simmer, K. Gençay, 2014, Journal of dental research.

STIM 1 and SLC 24 A 4 Are Critical for Enamel Maturation CliniCAl inVESTiGATiOnS

F. Seymen, J. Simmer, E. Tuna, 2014 .

Splicing Determines the Glycosylation State of Ameloblastin

P. Krebsbach, K. Gomi, T. Arai, 2007, Journal of dental research.

Enamelysin (Matrix Metalloproteinase 20)-deficient Mice Display an Amelogenesis Imperfecta Phenotype*

H. Birkedal‐Hansen, J. Simmer, J. D. Bartlett, 2002, The Journal of Biological Chemistry.

How Fluoride Protects Dental Enamel from Demineralization

J. Simmer, J. D. Bartlett, Nina C Hardy, 2020, Journal of International Society of Preventive & Community Dentistry.

Characterization of periodontal structures of enamelin-null mice.

W. Giannobile, R. Eber, H. Chan, 2014, Journal of periodontology.

Kallikrein-related peptidase-4 (KLK4): role in enamel formation and revelations from ablated mice

J. Simmer, J. D. Bartlett, 2014, Front. Physiol..

Bodyweight Assessment of Enamelin Null Mice

A. Chan, J. Simmer, J. Hu, 2012, BioMed research international.

Consequences for enamel development and mineralization resulting from loss of function of ameloblastin or enamelin.

A. Nanci, R. Wazen, J. Simmer, 2009, European journal of oral sciences.

Enamel Defects and Ameloblast-specific Expression in Enam Knock-out/lacZ Knock-in Mice*

M. McKee, J. T. Wright, G. Hunter, 2008, Journal of Biological Chemistry.

Identifying Promoter Elements Necessary for Enamelin Tissue-Specific Expression

L. Ye, P. Papagerakis, J. Simmer, 2008, Cells Tissues Organs.

Cloning and Characterization of the Mouse and Human Enamelin Genes

K. Forsman-Semb, C.H. Zhang, J. Simmer, 2001, Journal of dental research.

DPPI May Activate KLK4 during Enamel Formation

C. Tye, J. Simmer, J. D. Bartlett, 2009, Journal of dental research.

Ultrastructure of early amelogenesis in wild‐type, Amelx ‐/‐, and Enam ‐/‐ mice: enamel ribbon initiation on dentin mineral and ribbon orientation by ameloblasts

J. Simmer, Yuanyuan Hu, J. Hu, 2016, Molecular genetics & genomic medicine.

Evolution of Klk4 and enamel maturation in eutherians

K. Kawasaki, J. Simmer, J. Hu, 2014, Biological chemistry.

Novel MSX1 Frameshift Causes Autosomal-dominant Oligodontia

J. Simmer, J. Kim, J. Hu, 2006, Journal of dental research.

Developmental Disorders of Dentin

J. Simmer, J. Hu, Hong Zhang, 2014 .

Mutational analysis of candidate genes in 24 amelogenesis imperfecta families.

Jung‐Wook Kim, F. Seymen, J. Simmer, 2006, European journal of oral sciences.

Enamel malformations associated with a defined dentin sialophosphoprotein mutation in two families.

Jung‐Wook Kim, J. Simmer, Karen A Uston, 2011, European journal of oral sciences.

Root anomalies and dentin dysplasia in autosomal recessive hyperphosphatemic familial tumoral calcinosis (HFTC).

Murim Choi, F. Visioli, A. R. Vieira, 2015, Oral surgery, oral medicine, oral pathology and oral radiology.

Recessive Mutations in ACPT, Encoding Testicular Acid Phosphatase, Cause Hypoplastic Amelogenesis Imperfecta.

Z. Lee, E. Cho, T. Shin, 2016, American journal of human genetics.

Hereditary Dentin Defects

J. Simmer, J. Kim, 2007, Journal of dental research.

Osteogenic Differentiation Capacity of Porcine Dental Follicle Progenitor Cells

Y. Yamakoshi, J. Simmer, M. Honda, 2010, Connective tissue research.

Characterization of the mouse and human PRSS17 genes, their relationship to other serine proteases, and the expression of PRSS17 in developing mouse incisors.

J. Simmer, Chuhua Zhang, J. Hu, 2000, Gene.

Amelogenesis Imperfecta in Two Families with Defined AMELX Deletions in ARHGAP6

F. Seymen, J. Simmer, A. S. Richardson, 2012, PloS one.

Cleavage Site Specificity of MMP-20 for Secretory-stage Ameloblastin

M. Fukae, Y. Yamakoshi, J. Simmer, 2010, Journal of dental research.

Porcine kallikrein-4 activation, glycosylation, activity, and expression in prokaryotic and eukaryotic hosts.

Y. Yamakoshi, J. Simmer, J. D. Bartlett, 2002, European journal of oral sciences.

Characterization of a family with dominant hypophosphatasia.

J. Simmer, Chuhua Zhang, E. Mornet, 2000, European journal of oral sciences.

Establishment of porcine pulp-derived cell lines and expression of recombinant dentin sialoprotein and recombinant dentin matrix protein-1.

I. Ishikawa, Y. Yamakoshi, J. Simmer, 2007, European journal of oral sciences.

Cell proliferation and apoptosis in enamelin null mice.

M. McKee, J. Simmer, Charles E. Smith, 2011, European journal of oral sciences.

Developmental biology and genetics of dental malformations.

J. Simmer, J. Hu, 2007, Orthodontics & craniofacial research.

Functions of KLK4 and MMP-20 in dental enamel formation

P. Papagerakis, Y. Yamakoshi, J. Simmer, 2008, Biological chemistry.

Fluoride Affects Enamel Protein Content via TGF-β1-mediated KLK4 Inhibition

J. Simmer, J. D. Bartlett, Maiko Suzuki, 2014, Journal of dental research.

Fam83h null mice support a neomorphic mechanism for human ADHCAI

Murim Choi, Jung‐Wook Kim, Yuan-Ling Lee, 2015, Molecular genetics & genomic medicine.

Phenotypic Variation in Dentinogenesis Imperfecta/Dentin Dysplasia Linked to 4q21

C. Murdoch-Kinch, J. Simmer, J. Kim, 2006, Journal of dental research.

Proteomics and Genetics of Dental Enamel

P. Krebsbach, Y. Yamakoshi, J. Simmer, 2006, Cells Tissues Organs.

Porcine dentin sialoprotein glycosylation and glycosaminoglycan attachments

T. Nagano, Y. Yamakoshi, J. Simmer, 2011, BMC Biochemistry.

Enamel ribbons, surface nodules, and octacalcium phosphate in C57BL/6 Amelx −/− mice and Amelx +/− lyonization

J. Simmer, Yuanyuan Hu, J. Hu, 2016, Molecular genetics & genomic medicine.

Maturation stage enamel malformations in Amtn and Klk4 null mice.

R. Fajardo, J. Schmitz, J. Simmer, 2016, Matrix biology : journal of the International Society for Matrix Biology.

Target gene analyses of 39 amelogenesis imperfecta kindreds.

Jung‐Wook Kim, J. Simmer, J. Hu, 2011, European journal of oral sciences.

Dentin Sialophosphoprotein Is Processed by MMP-2 and MMP-20 in Vitro and in Vivo*

M. Fukae, Y. Yamakoshi, J. Simmer, 2006, Journal of Biological Chemistry.

A comparison of enamelin and amelogenin expression in developing mouse molars.

J. Simmer, Chuhua Zhang, J. Hu, 2001, European journal of oral sciences.

Enamelysin and kallikrein-4 mRNA expression in developing mouse molars.

J. Simmer, J. D. Bartlett, Shengxi Liu, 2002, European journal of oral sciences.

Taurodontism, variations in tooth number, and misshapened crowns in Wnt10a null mice and human kindreds

Murim Choi, Yuan-Ling Lee, K. C. Kent Lloyd, 2014, Molecular genetics & genomic medicine.

Enamel Formation and Amelogenesis Imperfecta

J. Simmer, Y. Chun, J. Hu, 2007, Cells Tissues Organs.

Human periodontal fibroblast response to enamel matrix derivative, amelogenin, and platelet-derived growth factor-BB.

D. Carnes, D. Cochran, J. Simmer, 2006, Journal of periodontology.

Novel PAX9 and COL1A2 Missense Mutations Causing Tooth Agenesis and OI/DGI without Skeletal Abnormalities

J. Simmer, J. Hu, Shih-Kai Wang, 2012, PloS one.

Overlapping DSPP Mutations Cause Dentin Dysplasia and Dentinogenesis Imperfecta

D. McKnight, J. Simmer, T. Hart, 2008, Journal of dental research.

Mutational hot spot in the DSPP gene causing dentinogenesis imperfecta type II

Young-Jae Kim, Sang-Hoon Lee, Jung‐Wook Kim, 2005, Human Genetics.

Effect of Kallikrein 4 Loss on Enamel Mineralization

J. Simmer, J. D. Bartlett, Charles E. Smith, 2011, The Journal of Biological Chemistry.

The nucleation and growth of calcium phosphate by amelogenin.

M. Snead, M. Paine, C. Howard, 2007, Journal of crystal growth.

How do enamelysin and kallikrein 4 process the 32-kDa enamelin?

M. Fukae, Y. Yamakoshi, J. Simmer, 2006, European journal of oral sciences.

Distal cis-regulatory elements are required for tissue-specific expression of enamelin (Enam).

L. Ye, P. Papagerakis, J. Simmer, 2008, European journal of oral sciences.

The spatial distribution of focal stacks within the inner enamel layer of mandibular mouse incisors

J. Simmer, Yuanyuan Hu, J. Hu, 2020, Journal of anatomy.

Quantitative analysis of the core 2D arrangement and distribution of enamel rods in cross‐sections of mandibular mouse incisors

J. Simmer, Yuanyuan Hu, J. Hu, 2018, Journal of anatomy.

Synergistic Mutations of LRP6 and WNT10A in Familial Tooth Agenesis

Yin-Lin Wang, Yi-Ping Wang, J. Simmer, 2021, Journal of personalized medicine.

The Modified Shields Classification and 12 Families with Defined DSPP Mutations

Yuan-Ling Lee, Kevin Y. Lee, F. Seymen, 2022, Genes.

Novel Mutations in GPR68 and SLC24A4 Cause Hypomaturation Amelogenesis Imperfecta

F. Seymen, J. Simmer, M. Koruyucu, 2021, Journal of personalized medicine.

Human and Mouse Enamel Phenotypes Resulting from Mutation or Altered Expression of AMEL, ENAM, MMP20 and KLK4

Yong Li, C. Gibson, J. T. Wright, 2008, Cells Tissues Organs.

Structural features, processing mechanism and gene splice variants of dentin sialophosphoprotein

Y. Yamakoshi, J. Simmer, 2018, The Japanese dental science review.

Porcine Dentin Sialophosphoprotein

Jung‐Wook Kim, T. Nagano, M. Fukae, 2008, Journal of Biological Chemistry.

Characterization of porcine dentin sialoprotein (DSP) and dentin sialophosphoprotein (DSPP) cDNA clones.

S. Oida, M. Fukae, Y. Yamakoshi, 2003, European journal of oral sciences.

Hypoplastic AI with Highly Variable Expressivity Caused by ENAM Mutations

S. Lee, S. Lee, H. Hyun, 2018, Journal of dental research.

Analyses of MMP20 Missense Mutations in Two Families with Hypomaturation Amelogenesis Imperfecta

Z. Lee, T. Shin, H. Hyun, 2017, Front. Physiol..

ITGB6 loss-of-function mutations cause autosomal recessive amelogenesis imperfecta.

Murim Choi, Jung‐Wook Kim, J. Simmer, 2014, Human molecular genetics.

MMP-20 mutation in autosomal recessive pigmented hypomaturation amelogenesis imperfecta

T. Hart, J. Simmer, J. D. Bartlett, 2005, Journal of Medical Genetics.

The Enamel Phenotype in Homozygous Fam83h Truncation Mice

Jung‐Wook Kim, J. Simmer, Yuanyuan Hu, 2019, Molecular genetics & genomic medicine.

Mutations in the pH-Sensing G-protein-Coupled Receptor GPR68 Cause Amelogenesis Imperfecta

Colin A. Johnson, A. Harada, C. Inglehearn, 2016, American journal of human genetics.

A post-classical theory of enamel biomineralization… and why we need one

J. Simmer, Charles E. Smith, A. S. Richardson, 2012, International Journal of Oral Science.

ENAM Mutations in Autosomal-dominant Amelogenesis Imperfecta

F. Seymen, J. Simmer, K. Gençay, 2005, Journal of dental research.

Translational Attenuation by an Intron Retention in the 5′ UTR of ENAM Causes Amelogenesis Imperfecta

Jung‐Wook Kim, J. Simmer, J. Hu, 2021, Biomedicines.

FAM83H and Autosomal Dominant Hypocalcified Amelogenesis Imperfecta

J. Simmer, H. Zhang, J. Kim, 2020, Journal of dental research.

MMP20 Proteolysis of Native Amelogenin Regulates Mineralization In Vitro

S. Y. Kwak, Y. Yamakoshi, J. Simmer, 2016, Journal of dental research.

Matrix Metalloproteinase-20 Over-Expression Is Detrimental to Enamel Development: A Mus musculus Model

J. Antone, C. Tye, J. Simmer, 2014, PloS one.

FAM83H Mutations Cause ADHCAI and Alter Intracellular Protein Localization

J. Simmer, J. Kim, J. Hu, 2011, Journal of dental research.

Transgenic Rescue of Enamel Phenotype in Ambn Null Mice

Y. Lu, P. Krebsbach, Y. Yamada, 2010, Journal of dental research.

Altered Enamelin Phosphorylation Site Causes Amelogenesis Imperfecta

J. Simmer, H. Chan, J. Hu, 2010, Journal of dental research.

Amelogenin-Collagen Interactions Regulate Calcium Phosphate Mineralization in Vitro*

E. Beniash, P. Fang, A. Deshpande, 2010, The Journal of Biological Chemistry.

Fam83h is Associated with Intracellular Vesicles and ADHCAI

J. Simmer, H. Chan, J. Kim, 2009, Journal of dental research.

Mutational spectrum of FAM83H: the C‐terminal portion is required for tooth enamel calcification

Jung‐Wook Kim, J. Simmer, J. D. Bartlett, 2008, Human mutation.

Amelogenin p.M1T and p.W4S Mutations Underlying Hypoplastic X-linked Amelogenesis Imperfecta

J-W Kim, J. T. Wright, J. Simmer, 2004, Journal of dental research.

A nonsense mutation in the enamelin gene causes local hypoplastic autosomal dominant amelogenesis imperfecta (AIH2).

G. Holmgren, J. Simmer, J. Hu, 2002, Human molecular genetics.

A nomenclature for X-linked amelogenesis imperfecta.

T. Hart, J. Simmer, J. T. Wright, 2002, Archives of oral biology.

AMBN mutations causing hypoplastic amelogenesis imperfecta and Ambn knockout‐NLS‐lacZ knockin mice exhibiting failed amelogenesis and Ambn tissue‐specificity

Jung‐Wook Kim, J. Simmer, A. S. Richardson, 2019, Molecular genetics & genomic medicine.

Relationships between protein and mineral during enamel development in normal and genetically altered mice.

J. Simmer, J. D. Bartlett, Charles E. Smith, 2011, European journal of oral sciences.

A Genetic Model for the Secretory Stage of Dental Enamel Formation.

Jung‐Wook Kim, Y. Yamakoshi, J. Simmer, 2021, Journal of structural biology.

MMP20, KLK4, and MMP20/KLK4 double null mice define roles for matrix proteases during dental enamel formation

J. Simmer, J. D. Bartlett, A. S. Richardson, 2015, Molecular genetics & genomic medicine.

Inhibitory effect of porcine amelogenins on spontaneous mineralization

E. Beniash, S. Kwak, Y. Yamakoshi, 2010 .

Porcine dentin matrix protein 1: gene structure, cDNA sequence, and expression in teeth.

Jung‐Wook Kim, Y. Yamakoshi, J. Simmer, 2006, European journal of oral sciences.

Proteomic analysis of enamel matrix using a two-dimensional protein fractionation system.

Y. Yamakoshi, J. Simmer, T. Iwata, 2006, European journal of oral sciences.

Effects of Fam83h overexpression on enamel and dentine formation.

Jung‐Wook Kim, J. Simmer, J. Hu, 2013, Archives of oral biology.

Ameloblast transcriptome changes from secretory to maturation stages

Yongsheng Bai, J. Simmer, A. S. Richardson, 2014, Connective tissue research.

LAMB3 Mutations Causing Autosomal-dominant Amelogenesis Imperfecta

F. Seymen, J. Simmer, K. Gençay, 2013, Journal of dental research.

Novel WDR72 Mutation and Cytoplasmic Localization

K. Nam, F. Seymen, J. Simmer, 2010, Journal of dental research.

Hypomaturation amelogenesis imperfecta caused by a novel SLC24A4 mutation.

F. Seymen, J. Simmer, E. Tuna, 2015, Oral surgery, oral medicine, oral pathology and oral radiology.

Mutations in RELT cause autosomal recessive amelogenesis imperfecta

K. Kawasaki, Jung‐Wook Kim, F. Seymen, 2018, Clinical genetics.

FAM20A Mutations Can Cause Enamel-Renal Syndrome (ERS)

Z. Baqain, J. Simmer, H. Daggag, 2013, PLoS genetics.

Premature Stop Codon in MMP20 Causing Amelogenesis Imperfecta

P. Papagerakis, J. Simmer, J. D. Bartlett, 2008, Journal of dental research.

FAM20A Mutations Associated with Enamel Renal Syndrome

M. Yeganeh, J. Simmer, J. Hu, 2014, Journal of dental research.

Alteration of Exon Definition Causes Amelogenesis Imperfecta

F. Seymen, J. Simmer, H. Zhang, 2020, Journal of dental research.

Porcine Dentin Sialoprotein Is a Proteoglycan with Glycosaminoglycan Chains Containing Chondroitin 6-Sulfate*

Jung‐Wook Kim, M. Fukae, Y. Yamakoshi, 2005, Journal of Biological Chemistry.

The dentin phosphoprotein repeat region and inherited defects of dentin

K. Kawasaki, Murim Choi, F. Seymen, 2015, Molecular genetics & genomic medicine.

Transcriptome analysis of gingival tissues of enamel-renal syndrome.

Yi-Ping Wang, J. Simmer, Wenjie Zhong, 2019, Journal of periodontal research.

Thermal denaturation of a recombinant mouse amelogenin: Circular dichroism and differential scanning calorimetric studies

M. Oobatake, V. Renugopalakrishnan, T. Yamasaki, 2005, Proteins.

Recessive Mutations in ACP4 Cause Amelogenesis Imperfecta

E. Cho, Y. Lee, F. Seymen, 2021, Journal of dental research.

Kallikrein 4 Is a Secreted Protein

J. Simmer, J. D. Bartlett, 2004, Cancer Research.

Odontogenesis-associated phosphoprotein truncation blocks ameloblast transition into maturation in OdaphC41*/C41* mice

K. Kawasaki, J. Simmer, T. Saunders, 2021, Scientific Reports.

A novel splice acceptor mutation in the DSPP gene causing dentinogenesis imperfecta type II

S. Lee, Sang-Hoon Lee, J. Simmer, 2004, Human Genetics.

A Novel De Novo SP6 Mutation Causes Severe Hypoplastic Amelogenesis Imperfecta

Ji-Soo Song, Jung‐Wook Kim, J. Simmer, 2021, Genes.

Candidate gene sequencing reveals mutations causing hypoplastic amelogenesis imperfecta

Z. Lee, T. Shin, H. Hyun, 2018, Clinical Oral Investigations.

Novel WDR72 Mutations Causing Hypomaturation Amelogenesis Imperfecta

F. Seymen, J. Simmer, M. Koruyucu, 2023, Journal of personalized medicine.

The dynamics of TGF-β in dental pulp, odontoblasts and dentin

T. Nagano, K. Gomi, Y. Yamakoshi, 2018, Scientific Reports.

Enamel proteins and proteases in Mmp20 and Klk4 null and double-null mice.

Y. Yamakoshi, J. Simmer, J. D. Bartlett, 2011, European journal of oral sciences.

Porcine SPARC: isolation from dentin, cDNA sequence, and computer model.

Jung‐Wook Kim, Y. Yamakoshi, J. Simmer, 2006, European journal of oral sciences.

Porcine N -Acetylgalactosamine 6-Sulfatase (GALNS) cDNA Sequence and Expression in Developing Teeth

S. Oida, Y. Yamakoshi, J. Simmer, 2002, Connective tissue research.

A dentin sialophosphoprotein mutation that partially disrupts a splice acceptor site causes type II dentin dysplasia.

Jung‐Wook Kim, J. Simmer, J. Hu, 2008, Journal of endodontics.

Biomimetic Enamel Regeneration Mediated by Leucine-Rich Amelogenin Peptide

S. Y. Kwak, S. Kwak, Y. Yamakoshi, 2017, Journal of dental research.

Structural Changes in Amelogenin upon Self-assembly and Mineral Interactions

E. Beniash, J. Simmer, H. Margolis, 2012, Journal of dental research.

Mouse Dspp frameshift model of human dentinogenesis imperfecta

Jung‐Wook Kim, J. Simmer, T. Saunders, 2021, Scientific Reports.

New Perspectives on Amelotin and Amelogenesis

J. Simmer, J. D. Bartlett, J. Simmer, 2015, Journal of dental research.

MMP20-generated amelogenin cleavage products prevent formation of fan-shaped enamel malformations

D. McComb, J. Simmer, J. D. Bartlett, 2021, Scientific Reports.

Enamel defects in Acp4R110C/R110C mice and human ACP4 mutations

F. Seymen, J. Simmer, T. Saunders, 2022, Scientific Reports.

Dentin Glycoprotein

M. Fukae, Y. Yamakoshi, J. Simmer, 2005, Journal of Biological Chemistry.

Dental malformations associated with biallelic MMP20 mutations

Jung‐Wook Kim, Yin-Lin Wang, B. Foster, 2020, Molecular genetics & genomic medicine.

Astacin Proteases Cleave Dentin Sialophosphoprotein (Dspp) to Generate Dentin Phosphoprotein (Dpp)

Y. Yamakoshi, J. Simmer, A. S. Richardson, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Protocols for Studying Formation and Mineralization of Dental Tissues In Vivo: Extraction Protocol for Isolating Dentin Matrix Proteins from Developing Teeth.

Y. Yamakoshi, J. Simmer, Mari M. Saito, 2019, Methods in molecular biology.

MMP20 Cleaves E-Cadherin and Influences Ameloblast Development

A. Nanci, Y. Yamakoshi, J. Simmer, 2011, Cells Tissues Organs.

Amelogenin stimulates bone sialoprotein (BSP) expression through fibroblast growth factor 2 response element and transforming growth factor-beta1 activation element in the promoter of the BSP gene.

E. Shimizu, Y. Ogata, J. Simmer, 2005, Journal of periodontology.

Dentin defects caused by a Dspp−1 frameshift mutation are associated with the activation of autophagy

J. Simmer, Ling Qi, Chuhua Zhang, 2023, Scientific reports.

Novel KLK4 Mutations Cause Hypomaturation Amelogenesis Imperfecta

F. Seymen, J. Simmer, M. Koruyucu, 2022, Journal of personalized medicine.

Kallikrein-related peptidase 4, matrix metalloproteinase 20, and the maturation of murine and porcine enamel.

J. Simmer, J. D. Bartlett, Charles E. Smith, 2011, European journal of oral sciences.

Role of amelogenin self-assembly in protein-mediated dental enamel formation

P. Fratzl, E. Beniash, S. Kwak, 2010 .

The nucleation and growth of calcium phosphate by amelogenin.

M. Snead, M. Paine, C. Howard, 2007, Journal of crystal growth.

Secreted protein kinases?

J. Simmer, Shih-Kai Wang, Andrew C Samann, 2013, Trends in biochemical sciences.

FAM20C Functions Intracellularly Within Both Ameloblasts and Odontoblasts In Vivo

J. Simmer, J. Hu, Shih-Kai Wang, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Dental enamel formation and its impact on clinical dentistry.

J. Simmer, J. Simmer, J. Hu, 2001, Journal of dental education.

A clinical and research protocol for characterizing patients with hypophosphatasia.

J. Simmer, J. Simmer, C. C. Hu, 1996, Pediatric dentistry.

Relationships between protein and mineral during enamel development in normal and genetically altered mice.

J. Simmer, J. D. Bartlett, Charles E. Smith, 2011, European journal of oral sciences.

MMP20 and KLK4 activation and inactivation interactions in vitro.

S. Oida, Y. Yamakoshi, J. Simmer, 2013, Archives of oral biology.

Leucine-rich Amelogenin Peptides Regulate Mineralization in vitro

E. Beniash, S. Kwak, Y. Yamakoshi, 2011, Journal of dental research.

Gingival crevicular fluid can degrade Emdogain and inhibit Emdogain-induced proliferation of periodontal ligament fibroblasts.

T. Salo, T. Sorsa, J. Simmer, 2010, Journal of periodontal research.

FAM20A Mutations Associated with Enamel Renal Syndrome

J. Simmer, S. Dugan, J. Roggenbuck, 2014, Journal of dental research.

Altered Enamelin Phosphorylation Site Causes Amelogenesis Imperfecta

J. Simmer, A. S. Richardson, J. Hu, 2010, Journal of dental research.

Translated Mutant DSPP mRNA Expression Level Impacts the Severity of Dentin Defects

Jung‐Wook Kim, F. Seymen, J. Simmer, 2022, Journal of personalized medicine.

Processing of Ameloblastin by MMP-20

I. Ishikawa, P. Krebsbach, Y. Yamakoshi, 2007, Journal of dental research.

The Non-Amelogenins: Ameloblastin and Enamelin

J. Simmer, J. Hu, Y. Chun, 2010 .