Kenneth M. Engstrom

发表

Discovery of adamantane ethers as inhibitors of 11beta-HSD-1: Synthesis and biological evaluation.

K. Longenecker, Jyoti R. Patel, H. Sham, 2007, Bioorganic & medicinal chemistry letters.

Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor.

A. Souers, G. Diaz, H. Sham, 2008, Journal of medicinal chemistry.

Process development of ABT-450 – A first generation NS3/4A protease inhibitor for HCV

Ahmad Y. Sheikh, Russell D. Cink, N. Nere, 2019, Tetrahedron.

Development of a Large-Scale Route to Glecaprevir: Synthesis of the Side Chain and Final Assembly

Russell D. Cink, S. Chemburkar, R. Henry, 2020 .

Improved synthesis of 3-substituted-4-amino-[3,2-c]-thienopyridines.

R. Rickert, S. Wagaw, Kenneth M. Engstrom, 2009, The Journal of organic chemistry.

Total Synthesis of (+)‐Pyrenolide D

Kenneth M. Engstrom, D. Gin, Mario R. Mendoza, 2001 .

Aminopiperidine indazoles as orally efficacious melanin concentrating hormone receptor-1 antagonists.

Ju Gao, Anil Vasudevan, John K Lynch, 2005, Bioorganic & medicinal chemistry letters.

Process Development of a Diacyl Glycerolacyltransferase-1 Inhibitor

Brian J. Kotecki, A. Souers, P. Kym, 2010 .

Development of a Large-Scale Route to Glecaprevir: Synthesis of the Macrocycle via Intramolecular Etherification

Dennie S. Welch, Russell D. Cink, N. Nere, 2020 .

Development of a Scalable Synthesis of Dipeptidyl Peptidase-4 Inhibitor ABT-279

Brian J. Kotecki, A. Sheikh, L. Bhagavatula, 2009 .

Synthesis of the glucuronide metabolite of ABT-751

R. Henry, Kenneth M. Engstrom, I. Marsden, 2007 .

Gram scale synthesis of the glucuronide metabolite of ABT-724.

S. Wagaw, Kenneth M. Engstrom, A. Stewart, 2006, The Journal of organic chemistry.

Implications of the Conformationally Flexible, Macrocyclic Structure of the First-Generation, Direct-Acting Anti-Viral Paritaprevir on Its Solid Form Complexity and Chameleonic Behavior.

Ahmad Y. Sheikh, Richard S. Hong, R. Henry, 2021, Journal of the American Chemical Society.

The Stability of N,N-Carbonyldiimidazole Toward Atmospheric Moisture

Ahmad Y. Sheikh, A. Sheikh, Kenneth M. Engstrom, 2014 .

Practical Considerations for the Formation of Acyl Imidazolides from Carboxylic Acids and N,N′-Carbonyldiimidazole: The Role of Acid Catalysis

Kenneth M. Engstrom, 2018, Organic Process Research & Development.

Chlorination at the 8-Position of a Functionalized Quinolone and the Synthesis of Quinolone Antibiotic ABT-492

M. J. Peterson, Elaine C. Lee, J. Tedrow, 2006 .

A Convergent Process for the Preparation of Adamantane 11-β-HSD-1 Inhibitors

J. Tolle, S. Wagaw, Kenneth M. Engstrom, 2008 .