L. Chovan

发表

Discovery of adamantane ethers as inhibitors of 11beta-HSD-1: Synthesis and biological evaluation.

K. Longenecker, Jyoti R. Patel, H. Sham, 2007, Bioorganic & medicinal chemistry letters.

Recombinant Antigens To Detect Toxoplasma gondii-Specific Immunoglobulin G and Immunoglobulin M in Human Sera by Enzyme Immunoassay

L. Howard, D. Aubert, I. Villena, 2000, Journal of Clinical Microbiology.

Novel antibacterial class: a series of tetracyclic derivatives.

N. Soni, Philip J. Merta, B. Beutel, 2006, Journal of medicinal chemistry.

Automatic mass spectrometry method development for drug discovery: application in metabolic stability assays.

Candace Black-Schaefer, L. Chovan, P. Dandliker, 2004, Rapid communications in mass spectrometry : RCM.

Novel Antibacterial Class

Xiaoan Ruan, N. Soni, Philip J. Merta, 2003, Antimicrobial Agents and Chemotherapy.

in Human Sera by Enzyme Immunoassay Immunoglobulin G and Immunoglobulin M-Specific Toxoplasma gondii Recombinant Antigens To Detect

M. J., Sheu, D. Aubert, 2000 .

Evaluation of different inhaled combination therapies (EDICT): a randomised, double-blind comparison of Seretide (50/250 microg bd Diskus vs. formoterol (12 microg bd) and budesonide (800 microg bd) given concurrently (both via Turbuhaler) in patients with moderate-to-severe asthma.

A. Chuchalin, E. Maggi, P. J. Whitehead, 2002, Respiratory medicine.

Synthesis and antibacterial activity of 5-methoxy- and 5-hydroxy-6-fluoro-1,8-naphthyridone-3-carboxylic acid derivatives.

Y. Gu, B. Beutel, L. Chovan, 2005, Bioorganic & medicinal chemistry letters.

Solid phase extraction as a faster alternative to HPLC: application to MS analysis of metabolic stability samples.

L. Chovan, P. Dandliker, Y. Lau, 2007, Journal of pharmaceutical sciences.

Adamantane sulfone and sulfonamide 11-β-HSD1 Inhibitors

K. Longenecker, R. Judge, Deanne F. Stolarik, 2007 .

Gemcitabine in locally advanced and metastatic non-small cell lung cancer: the Central European phase II study.

K. Krejcy, M. Krzakowski, J. Jassem, 1998, Lung cancer.

Pharmacokinetic Enhancement of the Hepatitis C Virus Protease Inhibitors VX-950 and SCH 503034 by Co-Dosing with Ritonavir

D. Kempf, J. Randolph, K. Marsh, 2007, Antiviral chemistry & chemotherapy.

Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.

R. Henry, H. Sham, D. Beno, 2007, Journal of medicinal chemistry.

Novel inhibitors of bacterial protein synthesis: structure-activity relationships for 1,8-naphthyridine derivatives incorporating position 3 and 4 variants.

N. Soni, R. Clark, Y. Gu, 2004, Bioorganic & medicinal chemistry letters.

Development and Clinical Evaluation of a Recombinant-Antigen-Based Cytomegalovirus Immunoglobulin M Automated Immunoassay Using the Abbott AxSYM Analyzer

George L. Wright, M. Clements, T. Lazzarotto, 2000, Journal of Clinical Microbiology.

4 Pharmacokinetic boosting of VX-950, an inhibitor of HCV protease, by co-dosing with ritonavir

D. Kempf, J. Randolph, K. Marsh, 2006 .

From Bacterial Genomes to Novel Antibacterial Agents: Discovery, Characterization, and Antibacterial Activity of Compounds that Bind to HI0065 (YjeE) from Haemophilus influenzae

P. Hajduk, K. Comess, Liping Yu, 2007, Chemical biology & drug design.

Solution structure and function of a conserved protein SP14.3 encoded by an essential Streptococcus pneumoniae gene.

A. Gunasekera, E. Olejniczak, S. Fesik, 2001, Journal of molecular biology.

Genome Scanning in Haemophilus influenzae for Identification of Essential Genes

K. Reich, L. Chovan, P. Hessler, 1999, Journal of bacteriology.

Quantitative Immunolocalization of a P29 Protein (GRA7), a New Antigen of Toxoplasma Gondii

A. Bonhomme, H. Burlet, D. Aubert, 1998, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

The DNA-binding protein pUL57 of human cytomegalovirus: comparison of specific immunoglobulin M (IgM) reactivity with IgM reactivity to other major target antigens

T. Lazzarotto, M. Landini, L. Chovan, 1996, Clinical and diagnostic laboratory immunology.

A Strategy for Discovery of Novel Broad-Spectrum Antibacterials Using a High-Throughput Streptococcus pneumoniae Transcription/Translation Screen

L. Traphagen, U. Warrior, N. Soni, 2004, Journal of biomolecular screening.

Rapid hit to lead evaluation of pyrazolo[3,4-d]pyrimidin-4-one as selective and orally bioavailable mGluR1 antagonists.

J. Brioni, R. Moreland, P. Honore, 2007, Bioorganic & medicinal chemistry letters.

Adamantane sulfone and sulfonamide 11-beta-HSD1 Inhibitors.

K. Longenecker, R. Judge, Deanne F. Stolarik, 2007, Bioorganic & medicinal chemistry letters.