Nedyalka Radeva

Structure-based design of inhibitors of the aspartic protease endothiapepsin by exploiting dynamic combinatorial chemistry.

Gerhard Klebe, Nedyalka Radeva, Constantinos Potamitis, 2014, Angewandte Chemie.

Active Site Mapping of an Aspartic Protease by Multiple Fragment Crystal Structures: Versatile Warheads To Address a Catalytic Dyad.

G. Klebe, A. Heine, M. Weiss, 2016, Journal of medicinal chemistry.

From Active-Site Mapping to Lead Discovery using Fragment-based Approaches on the Aspartic protease Endothiapepsin

Nedyalka Radeva, N. Radeva, 2016 .

High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits.

Gerhard Klebe, Michael Krug, Manfred S Weiss, 2016, Structure.

A False-Positive Screening Hit in Fragment-Based Lead Discovery: Watch out for the Red Herring.

G. Klebe, U. Linne, A. Heine, 2017, Angewandte Chemie.

Experimental Active-Site Mapping by Fragments: Hot Spots Remote from the Catalytic Center of Endothiapepsin.

G. Klebe, A. Heine, M. Weiss, 2016, Journal of medicinal chemistry.

Structure-Based Optimization of Inhibitors of the Aspartic Protease Endothiapepsin

G. Klebe, M. Mondal, Nedyalka Radeva, 2015, International journal of molecular sciences.

Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment‐Based Drug Design Facilitated by Dynamic Combinatorial Chemistry

G. Klebe, S. Otto, M. Mondal, 2016, Angewandte Chemie.