H. Köster

Structure-based design of inhibitors of the aspartic protease endothiapepsin by exploiting dynamic combinatorial chemistry.

Gerhard Klebe, Nedyalka Radeva, Constantinos Potamitis, 2014, Angewandte Chemie.

A small nonrule of 3 compatible fragment library provides high hit rate of endothiapepsin crystal structures with various fragment chemotypes.

Gerhard Klebe, Tobias Craan, Lars Neumann, 2011, Journal of medicinal chemistry.

Tracing binding modes in hit-to-lead optimization: chameleon-like poses of aspartic protease inhibitors.

Gerhard Klebe, Wibke E Diederich, G. Klebe, 2015, Angewandte Chemie.

Experimental and Computational Active Site Mapping as a Starting Point to Fragment‐Based Lead Discovery

G. Klebe, A. Heine, H. Köster, 2012, ChemMedChem.

One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit Lists

Timo Krotzky, Gerhard Klebe, Nedyalka Radeva, 2015, ChemMedChem.

Structure-based design of inhibitors of the aspartic protease endothiapepsin by exploiting dynamic combinatorial chemistry.

G. Klebe, A. Park, C. Potamitis, 2014, Angewandte Chemie.