D. Goff

发表

Discovery of nanomolar ligands for 7-transmembrane G-protein-coupled receptors from a diverse N-(substituted)glycine peptoid library.

D C Spellmeyer, E J Martin, Liang Wang, 1994, Journal of medicinal chemistry.

Diverse alkaloid-like structures from a common building block

D. Goff, 2013 .

The synthesis of 2-imldazolidones on solid support by tandem aminoacylation/Michael addition

D. Goff, 1998 .

R-253 Disrupts Microtubule Networks in Multiple Tumor Cell Lines

Y. Hitoshi, D. Payan, E. Pali, 2006, Clinical Cancer Research.

Discovery and Characterization of Substituted Diphenyl Heterocyclic Compounds as Potent and Selective Inhibitors of Hepatitis C Virus Replication

D. Payan, K. Qu, T. Kinsella, 2008, Antimicrobial Agents and Chemotherapy.

Substituted 2-iminothiolanes: reagents for the preparation of disulfide cross-linked conjugates with increased stability.

S. Carroll, D. Goff, 1990, Bioconjugate chemistry.

Nmr Structural Characterization of Oligo-N-Substituted Glycine Lead Compounds from a Combinatorial Library

D. Spellmeyer, E. Bradley, J. Blaney, 2004, Molecular Diversity.

Synthesis of nickel(II) isobacteriochlorins from nickel(II) complexes of chlorophyll derivatives

Kevin M. Smith, Kevin M Smith, D. Goff, 1985 .

Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-Imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Synthase Kinase 3.

Sean P. Brown, Kirk W. Johnson, Z. Ni, 2017, Journal of medicinal chemistry.

Exercise performance and peripheral vascular insufficiency improve with AMPK activation in high-fat diet-fed mice.

V. Markovtsov, R. Singh, Y. Hitoshi, 2014, American journal of physiology. Heart and circulatory physiology.

NMR spectra of porphyrins. 18. A ring-current model for chlorophyll derivatives

Kevin M. Smith, R. J. Abraham, Kevin M Smith, 1982 .

Efforts towards a Noyori reduction of a 3-fluorpiperidin-4-one with dynamic kinetic resolution

D. Goff, Rajinder Singh, S. Shaw, 2021 .

Enhanced stability in vitro and in vivo of immunoconjugates prepared with 5-methyl-2-iminothiolane.

A. Kung, S. Carroll, S. L. Bernhard, 1994, Bioconjugate chemistry.

Structure activity relationships leading to the identification of the indirect activator of AMPK, R419.

V. Markovtsov, Y. Hitoshi, D. Payan, 2022, Bioorganic & medicinal chemistry.

Substituted 2-iminothiolanes: reagents for the preparation of disulfide cross-linked conjugates with increased stability.

S. Carroll, D. Goff, 1990, Bioconjugate chemistry.

The NMR spectra of porphyrins: 22—Ring current effects in chlorins versus porphyrins

R. J. Abraham, Kevin M Smith, D. Goff, 1983 .

Discovery and Characterization of Substituted Diphenyl Heterocyclic Compounds as Potent and Selective Inhibitors of Hepatitis C Virus Replication (cid:1)

D. Payan, K. Qu, T. Kinsella, 2008 .

The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma

E. Montgomery, G. Riggins, J. Eshleman, 2010, Cancer biology & therapy.

Meso substitution of chlorophyll derivatives: direct route for transformation of bacteriopheophorbides d into bacteriopheophorbides c

Kevin M. Smith, Kevin M Smith, D. Goff, 1985 .

Solid-phase synthesis of defined 1,4-benzodiazepine-2,5-dione mixtures

R. Zuckermann, D. Goff, 1995 .

Solid-Phase Synthesis of Highly Substituted Peptoid 1(2H)-Isoquinolinones

R. Zuckermann, D. Goff, 1995 .

THE PREPARATION OF 2,4-DISUBSTITUTED THIAZOLES ON SOLID SUPPORT

D. Goff, Juan Fernández, 1999 .

THE SYNTHESIS OF 2-OXOPIPERAZINES BY INTRAMOLECULAR MICHAEL ADDITION ON SOLID SUPPORT

R. Zuckermann, D. Goff, 1996 .

Combinatorial synthesis of indolizines on solid support

D. Goff, 1999 .

Proton NMR study of the conformation of ring D and its side chains in chlorophyll derivatives

R. J. Abraham, Kevin M Smith, D. Goff, 1981 .

Experimental, Structural and Theoretical Models of Bacteriochlorophylls a, d and g

L. K. Hanson, M. Zerner, J. Head, 1985 .

The NMR spectra of porphyrins. 27†—proton NMR spectra of chlorophyll-a and pheophytin-a

R. J. Abraham, Kevin M Smith, D. Goff, 1984 .

Developing a general strategy for the solid supported synthesis of heterocycles: Applications to the generation of molecular diversity and drug discovery

M. Desai, R. Zuckermann, S. Subramanian, 1997 .

Cleavage of methoxymethyl ethers with boron trichloride. A convenient, versatile preparation of chloromethyl ether derivatives

C. Bedford, D. Goff, J. Bottaro, 1986 .

Enantioselective synthesis of cis-3-fluoropiperidin-4-ol, a building block for medicinal chemistry.

M. Irving, D. Goff, Rajinder Singh, 2013, The Journal of organic chemistry.

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 4. Effect of various side-chain substituents on therapeutic activity against anticholinesterase intoxication.

D. Taylor, C. Bedford, D. Goff, 1991, Journal of medicinal chemistry.

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 3. Synthesis and evaluation of (alkenyloxy)-, (alkynyloxy)-, and (aralkyloxy)methyl quaternarized 2-[(hydroxyimino)methyl]-1-alkylimidazolium halides as reactivators and therapy for soman intoxication.

R. Howd, C. Bedford, D. Goff, 1989, Journal of medicinal chemistry.

NMR spectra of porphyrins. 28. Detailed solution structure of a bacteriochlorophyllide d dimer

R. J. Abraham, Kevin M Smith, D. Goff, 1986 .

Intermediates in the formation of the chlorophyll isocyclic ring.

Y. Wong, D. Goff, K. Smith, 1985, Plant physiology.

NMR spectra of porphyrins. Part 31. Ring currents in hydroporphyrins

R. J. Abraham, Kevin M Smith, C. Medforth, 1987 .

Bacteriochlorophylls-d from Chlorobium vibrioforme: chromatographic separations and structural assignments of the methyl bacteriopheophorbides

Kevin M. Smith, Kevin M Smith, D. Goff, 1985 .

Anion radicals of bacteriochlorophylls c, d, and e. Likely electron acceptors in the primary photochemistry of green and brown photosynthetic bacteria

L. K. Hanson, Kevin M Smith, D. Goff, 1983 .

NMR Spectra of Porphyrins. Part 37. The Structure of the Methyl Pyrochlorophyllide a Dimer.

R. J. Abraham, Kevin M Smith, A. Rowan, 1990 .

N.m.r. spectra of porphyrins. Part 37. The structure of the methyl pyrochlorophyllide a dimer

R. J. Abraham, Kevin M Smith, A. Rowan, 1989 .

NMR spectra of porphyrins. XXIX: Conformation of the propionic ester side chain in chlorophyll derivatives

R. J. Abraham, Kevin M Smith, D. Goff, 1987 .

Isolation and characterization of two new bacteriochlorophylls d bearing neopentyl substituents

Kevin M. Smith, Kevin M Smith, D. Goff, 1983 .

R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer.

Y. Hitoshi, D. Payan, Weiqun Li, 2010, Cancer research.

R 428 , a Selective Small Molecule Inhibitor of Axl Kinase , Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer

Y. Hitoshi, D. Payan, Weiqun Li, 2010 .

Developing DYRK inhibitors derived from the meridianins as a means of increasing levels of NFAT in the nucleus.

D. Payan, T. Kinsella, J. McLaughlin, 2017, Bioorganic & medicinal chemistry letters.

Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo.

Kirk W. Johnson, Sylvia Ma, J. Nuss, 2003, Diabetes.

A peptoid based synthesis of di- and tri-substituted 2-oxopiperazines on solid support

D. Goff, 1998 .

AMPK Activation through Mitochondrial Regulation Results in Increased Substrate Oxidation and Improved Metabolic Parameters in Models of Diabetes

B. Viollet, V. Markovtsov, L. Boros, 2013, PloS one.

THE MESO SUBSTITUTION OF CHLOROPHYLL DERIVATIVES: DIRECT ROUTE FOR TRANSFORMATION OF BACTERIOPHEOPHORBIDES D INTO BACTERIOPHEOPHORBIDES C.

Kevin M. Smith, D. Goff, D. Simpson, 1985 .

CHLOROPHYLL-A DERIVATIVES IN PHOTODYNAMIC THERAPY : EFFECT OF POSITION OF HEPTYL ETHER SIDE-CHAINS ON IN VIVO PHOTOSENSITIZING ACTIVITY

Kevin M. Smith, T. Dougherty, R. Pandey, 1996 .

Discovery of dual Axl/VEGF-R2 inhibitors as potential anti-angiogenic and anti-metastatic drugs for cancer chemotherapy.

Weiqun Li, D. Goff, Raj K. Singh, 2017, Bioorganic & medicinal chemistry letters.

Selective Small Molecule Inhibitor of Axl Kinase , Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer

Y. Hitoshi, D. Payan, Weiqun Li, 2010 .

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 5. Structure-activity relationships for side-chain nitro-, sulfone-, amino-, and aminosulfonyl-substituted analogues for therapy against anticholinesterase intoxication.

K. Lin, C. Bedford, D. Goff, 1991, Journal of medicinal chemistry.

Quaternary Salts of 2-((Hydroxyimino)methyl)imidazole. Part 2. Preparation and in vitro and in vivo Evaluation of 1-(Alkoxymethyl)-2-((hydroxyimino)methyl)-3-methylimidazolium Halides for Reactivation of Organophosphorus-Inhibited Ace

R. O. Pick, R. Howd, C. Bedford, 1989 .

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 2. Preparation and in vitro and in vivo evaluation of 1-(alkoxymethyl)-2-[(hydroxyimino)methyl]-3-methylimida zolium halides for reactivation of organophosphorus-inhibited acetylcholinesterases.

R. O. Pick, R. Howd, C. Bedford, 1989, Journal of Medicinal Chemistry.

Cyclopeptide Alkaloids. Phencyclopeptines From the Polymorphic Species Ceanothus integerrimus.

J. Lagarias, H. Rapoport, D. Goff, 1979, Journal of natural products.

Global metabolite profiling of mice with high-fat diet-induced obesity chronically treated with AMPK activators R118 or metformin reveals tissue-selective alterations in metabolic pathways

V. Markovtsov, Y. Hitoshi, D. Payan, 2014, BMC Research Notes.

Exercise performance and peripheral vascular insufficiency improve with AMPK activation in high-fat diet-fed mice.

V. Markovtsov, R. Singh, Y. Hitoshi, 2014, American journal of physiology. Heart and circulatory physiology.

Chirality and structures of bacteriochlorophylls d

Kevin M Smith, D. Goff, K. Barkigia, 1982 .