D. Selwood

T. Wirth, S. Ylä-Herttuala, M. Kaikkonen, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Big conductance calcium‐activated potassium channel openers control spasticity without sedation

A. Irving, G. Giovannoni, S. Jackson, 2017, British journal of pharmacology.

Infection Counter: Automated Quantification of in Vitro Virus Replication by Fluorescence Microscopy

G. Towers, J. Grove, D. Selwood, 2016, Viruses.

Emerging small-molecule treatments for multiple sclerosis: focus on B cells

S. Tsirka, D. Selwood, K. Thompson, 2019, F1000Research.

4′-Thionucleosides via in situ Pyranose-Furanose Rearrangements: A Short Synthesis of the Antiherpes Agent 2′-Deoxy-5-ethyl-4′- thiouridine via Direct Coupling of a Silylated Pyrimidine Base with a 4-Thiopyranose Sugar.

D. Selwood, K. Jandu, 1995 .

Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction†

C. Allerston, P. Driscoll, S. Djordjević, 2010, Journal of medicinal chemistry.

A concise approach to the epidithiodiketopiperazine (ETP) core

A. Aliev, S. Hilton, D. Selwood, 2006 .

Mitochondrial Permeability Transition: A Molecular Lesion with Multiple Drug Targets.

M. Duchen, G. Szabadkai, D. Selwood, 2019, Trends in pharmacological sciences.

Selective Inhibition of the Mitochondrial Permeability Transition Pore Protects against Neurodegeneration in Experimental Multiple Sclerosis*

Julia M. Hill, M. Duchen, A. Coker, 2015, The Journal of Biological Chemistry.

Disruption of methylarginine metabolism impairs vascular homeostasis

P. Vallance, J. Murray-Rust, N. McDonald, 2007, Nature Medicine.

Endothelial C-type natriuretic peptide maintains vascular homeostasis.

M. Caulfield, P. Gane, A. Ahluwalia, 2014, The Journal of clinical investigation.

Previous Title: Oligodendrocytes, BK channels and remyelination

D. Selwood, David Baker, Maddalena Rupnik, 2021 .

Characterisation of Transcriptional Changes in the Spinal Cord of the Progressive Experimental Autoimmune Encephalomyelitis Biozzi ABH Mouse Model by RNA Sequencing

G. Pryce, D. Selwood, D. Baker, 2016, PloS one.

Control of spasticity in a multiple sclerosis model using central nervous system‐excluded CB1 cannabinoid receptor agonists

A. Montpetit, A. Thompson, C. Ledent, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Lesional-targeting of neuroprotection to the inflammatory penumbra in experimental multiple sclerosis.

J. Garthwaite, S. Joel, G. Giovannoni, 2014, Brain : a journal of neurology.

Genetic Background Can Result in a Marked or Minimal Effect of Gene Knockout (GPR55 and CB2 Receptor) in Experimental Autoimmune Encephalomyelitis Models of Multiple Sclerosis

G. Michael, G. Giovannoni, S. Jackson, 2013, PloS one.

Neuroprotection in Experimental Autoimmune Encephalomyelitis and Progressive Multiple Sclerosis by Cannabis-Based Cannabinoids

G. Giovannoni, G. Pryce, D. Selwood, 2015, Journal of Neuroimmune Pharmacology.

A Bifurcated Proteoglycan Binding Small Molecule Carrier for siRNA Delivery

R. Melander, A. MacRobert, D. Selwood, 2014, Chemical biology & drug design.

siRNA Delivery: From Lipids to Cell‐penetrating Peptides and Their Mimics

D. Selwood, Lorcan P. Browne, M. Gooding, 2012, Chemical biology & drug design.

Gyrase B Inhibitor Impairs HIV-1 Replication by Targeting Hsp90 and the Capsid Protein*

Richard G. Jenner, A. Fassati, P. Gane, 2010, The Journal of Biological Chemistry.

HIV-1 capsid is involved in post-nuclear entry steps

G. Nicastro, I. Taylor, J. Luban, 2016, Retrovirology.

Imatinib binding and cKIT inhibition is abrogated by the cKIT kinase domain I missense mutation Val654Ala

David Selwood, C. Boshoff, J. Whelan, 2005, Molecular Cancer Therapeutics.

The effect of two novel analogues of antimycin A on oxygen consumption and survival of filarial nematodes in vitro.

D. J. Hayes, J. Comley, D. Selwood, 1990, Molecular and biochemical parasitology (Print).

Glucose transport in Acanthocheilonema viteae

D. J. Hayes, D. Selwood, 1990, Parasitology.

A NEW, EFFICIENT SYNTHESIS OF 5-UNDECYL-6-HYDROXY-4,7-DIOXOBENZOTHIAZOLE (UHDBT), A POTENT ELECTRON-TRANSPORT INHIBITOR

David Selwood, Karamjit S. Jandu, D. Selwood, 1988 .

2- and 3-substituted imidazo[1,2-a]pyrazines as inhibitors of bacterial type IV secretion

K. Walldén, G. Waksman, P. Gane, 2014, Bioorganic & medicinal chemistry.

VEGFA, B, C: Implications of the C-Terminal Sequence Variations for the Interaction with Neuropilins

M. Zloh, S. Djordjević, D. Selwood, 2022, Biomolecules.

Characterization of a Bicyclic Peptide Neuropilin-1 (NP-1) Antagonist (EG3287) Reveals Importance of Vascular Endothelial Growth Factor Exon 8 for NP-1 Binding and Role of NP-1 in KDR Signaling*

P. Driscoll, Richard Harris, I. Zachary, 2006, Journal of Biological Chemistry.

Peptides encoded by exon 6 of VEGF inhibit endothelial cell biological responses and angiogenesis induced by VEGF.

S. Soker, I. Zachary, D. Selwood, 2001, Biochemical and biophysical research communications.

Anti-chemorepulsive Effects of Vascular Endothelial Growth Factor and Placental Growth Factor-2 in Dorsal Root Ganglion Neurons Are Mediated via Neuropilin-1 and Cyclooxygenase-derived Prostanoid Production*

David Selwood, I. Zachary, Azadeh Bagherzadeh, 2004, Journal of Biological Chemistry.

The β4-Subunit of the Large-Conductance Potassium Ion Channel KCa1.1 Regulates Outflow Facility in Mice

D. Baker, E. Lütjen-Drecoll, W. Stamer, 2020, Investigative ophthalmology & visual science.

Aurora A and B kinases as targets for cancer: will they be selective for tumors?

C. Visintin, D. Selwood, Ashley N. Jarvis, 2006, Expert review of anticancer therapy.

Ablation of Neuropilin 1 from glioma-associated microglia and macrophages slows tumor progression

David Selwood, Kenneth R. Shroyer, Stella E. Tsirka, 2016, Oncotarget.

Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis.

P. Vallance, P. Gane, J. Leiper, 2007, Bioorganic & medicinal chemistry letters.

Issue Information

D. Selwood, I. Balamurugan, 2018 .

Oligodendrocytes, BK channels and the preservation of myelin

D. Selwood, David Baker, Maddalena Rupnik, 2021, F1000Research.

Oligodendrocytes, BK channels and the preservation of myelin

D. Selwood, David Baker, Maddalena Rupnik, 2021, F1000Research.

Oligodendrocytes, BK channels and remyelination [version 1; peer review: awaiting peer review]

D. Selwood, David Baker, Maddalena Rupnik, 2021 .

Two- and Three-dimensional Rings in Drugs

D. Selwood, Shipra Malhotra, Matteo Aldeghi, 2014, Chemical biology & drug design.

The Cannabinoid Receptors. Edited by Patricia H. Reggio.

D. Selwood, 2009 .

Regulation of GTP Cyclohydrolase I by Estrogen

A. Hingorani, P. Vallance, A. Ahluwalia, 2002 .

N10‐carbonyl‐substituted phenothiazines inhibiting lipid peroxidation and associated nitric oxide consumption powerfully protect brain tissue against oxidative stress

Tomas C. Bellamy, J. Garthwaite, D. Selwood, 2019, Chemical biology & drug design.

Phosphoinositide Modulation of Heteromeric Kv1 Channels Adjusts Output of Spiral Ganglion Neurons from Hearing Mice

D. McAlpine, D. Jagger, D. Selwood, 2015, The Journal of Neuroscience.

Faculty Opinions recommendation of The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility.

D. Selwood, 2019, Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.

A peptide encoded by exon 6 of VEGF (EG3306) inhibits VEGF-induced angiogenesis in vitro and ischaemic retinal neovascularisation in vivo.

R. Ali, J. Bainbridge, I. Zachary, 2003, Biochemical and biophysical research communications.

VSN16S, an agonist of the cannabinoid receptor, reduces IOP profiles and exhibits neuroprotective properties in a rat model of glaucoma

M. Cordeiro, Li Guo, V. Luong, 2022, Acta ophthalmologica.

Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production in Regulatory T-Cells

C. Milagre, S. Tsirka, P. Frankel, 2018, Journal of medicinal chemistry.

A mitochondrial-targeted cyclosporin A with high binding affinity for cyclophilin D yields improved cytoprotection of cardiomyocytes

M. Crompton, D. Selwood, H. Dube, 2011, The Biochemical journal.

Biophysical screening methods for extracellular domain peptide receptors, application to natriuretic peptide receptor C ligands

A. Hobbs, D. Selwood, F. Mota, 2018, Chemical biology & drug design.

Small-molecule mimics of an alpha-helix for efficient transport of proteins into cells.

C. Boshoff, K. Stoeber, H. Laman, 2007, Nature methods.

Oligodendrocytes, BK channels and remyelination [version 1; peer review: 1 approved, 1 approved with reservations]

D. Selwood, David Baker, Maddalena Rupnik, 2021 .

A new patient‐derived iPSC model for dystroglycanopathies validates a compound that increases glycosylation of α‐dystroglycan

Fengtang Yang, F. Muntoni, D. Stemple, 2019, EMBO reports.

A Humanized Antibody against LRG1 that Inhibits Angiogenesis and Reduces Retinal Vascular Leakage

J. Greenwood, M. Gourlaouen, S. Liyanage, 2020, bioRxiv.

Neuroprotection in an Experimental Model of Multiple Sclerosis via Opening of Big Conductance, Calcium-Activated Potassium Channels

G. Giovannoni, G. Pryce, D. Selwood, 2023, Pharmaceuticals.

Improved fluorescence assays to measure the defects associated with F508del‐CFTR allow identification of new active compounds

J. Reymond, E. Langron, D. Selwood, 2017, British journal of pharmacology.

A new small molecule inhibitor of soluble guanylate cyclase

J. Garthwaite, C. Allerston, P. Gane, 2015, Bioorganic & medicinal chemistry.

Surface plasmon resonance using the catalytic domain of soluble guanylate cyclase allows the detection of enzyme activators☆

J. Garthwaite, C. Allerston, D. Selwood, 2014, Bioorganic & medicinal chemistry letters.

Vascular pharmacology of a novel cannabinoid‐like compound, 3‐(5‐dimethylcarbamoyl‐pent‐1‐enyl)‐N‐(2‐hydroxy‐1‐methyl‐ethyl)benzamide (VSN16) in the rat

S. Gardiner, T. Bennett, C. Visintin, 2007, British journal of pharmacology.

New synthesis of KT5823 indolocarbazole aglycone

D. Madge, D. Selwood, G. Burtin, 2000 .

New Synthesis of KT5823 Indolocarbazole Aglycone.

D. Madge, D. Selwood, G. Burtin, 2001 .

Solution-Phase parallel synthesis of 5-carboxamido 1-benzyl-3-(3-dimethylaminopropyloxy)-1H-pyrazoles as activators of soluble guanylate cyclase with improved oral bioavailability.

R. Glen, D. Selwood, G. Wishart, 2001, Bioorganic & medicinal chemistry letters.

Discovery of a novel fluorescent chemical probe suitable for evaluation of neuropilin‐1 binding of small molecules

S. Djordjević, D. Selwood, F. Mota, 2020, Drug development research.

Selective substrate-based inhibitors of mammalian dimethylarginine dimethylaminohydrolase.

P. Vallance, J. Leiper, D. Selwood, 2005, Journal of medicinal chemistry.

Beyond the Hundred Dollar Genome – Drug Discovery Futures

D. Selwood, 2013, Chemical biology & drug design.

Lesional-targeting of neuroprotection to the inflammatory penumbra in experimental multiple sclerosis.

J. Garthwaite, S. Joel, G. Giovannoni, 2014, Brain : a journal of neurology.