S. Brass

A small nonrule of 3 compatible fragment library provides high hit rate of endothiapepsin crystal structures with various fragment chemotypes.

Gerhard Klebe, Tobias Craan, Lars Neumann, 2011, Journal of medicinal chemistry.

Unexpected Novel Binding Mode of Pyrrolidine‐Based Aspartyl Protease Inhibitors: Design, Synthesis and Crystal Structure in Complex with HIV Protease

G. Klebe, A. Heine, G. Müller, 2006, ChemMedChem.

Computer‐Aided Design and Synthesis of Nonpeptidic Plasmepsin II and IV Inhibitors

Gerhard Klebe, Christoph A Sotriffer, Wibke E Diederich, 2008, ChemMedChem.

Facile synthesis of substituted 2,3,4,7-tetrahydro-1H-azepines via ring-closing metathesis

S. Brass, H. Gerber, W. Diederich, 2006 .

Synthesis of 2,3,4,7-tetrahydro-1H-azepines as privileged ligand scaffolds for the design of aspartic protease inhibitors via a ring-closing metathesis approach

Christof Gerlach, J. Böttcher, S. Brass, 2006 .

Fragment‐Based Lead Discovery: Screening and Optimizing Fragments for Thermolysin Inhibition

Gerhard Klebe, Katrin Silber, Hans-Dieter Gerber, 2010, ChemMedChem.

Computer‐Aided Design and Synthesis of Nonpeptidic Plasmepsin II and IV Inhibitors

G. Klebe, C. Sotriffer, S. Brass, 2008, ChemMedChem.