J. Zuegg

发表

Drug-likeness and increased hydrophobicity of commercially available compound libraries for drug screening.

Matthew A Cooper, Johannes Zuegg, M. Cooper, 2012, Current topics in medicinal chemistry.

Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin Peptides

Matthew A. Cooper, Johannes Zuegg, Mark A. T. Blaskovich, 2016, ACS infectious diseases.

Molecular diversity through sugar scaffolds.

Bernd Becker, Judy Halliday, Wim Meutermans, 2003, Drug discovery today.

Repository In vitro inhibitory evaluation of novel amine and amide compounds against the post-translational modifier enzyme

R. Barnard, J. Zuegg, Christian Fercher, 2019 .

Targeting Bacterial Cell Wall Peptidoglycan Synthesis by Inhibition of Glycosyltransferase Activity

W. Meutermans, M. Conrad, M. Mesleh, 2016, Chemical biology & drug design.

Crystal Structures of the PBP2 Glycosyltransferase Domain: New Opportunities for Antibacterial Drug Design

W. Meutermans, J. Zuegg, 2007, ChemMedChem.

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice

T. Bailey, J. Carroll, B. Black, 2017, eLife.

Discovery of Cephalosporin-3´-Diazeniumdiolates that show Dual Antibacterial and Antibiofilm Effects against Pseudomonas aeruginosa Clinical Cystic Fibrosis Isolates and Efficacy in a Murine Respiratory Infection Model.

S. Rice, M. Naimi-Jamal, S. Faust, 2020, ACS infectious diseases.

Variation of the net charge, lipophilicity, and side chain flexibility in Dmt(1)-DALDA: Effect on Opioid Activity and Biodistribution.

M. Cooper, P. Schiller, E. Wynendaele, 2012, Journal of medicinal chemistry.

Nontoxic Cobalt(III) Schiff Base Complexes with Broad‐Spectrum Antifungal Activity

Amy K. Cain, Justin J. Wilson, Alysha G. Elliott, 2020, Chemistry.

Three‐dimensional structures of enzyme‐substrate complexes of the hydroxynitrile lyase from hevea brasiliensis

K. Gruber, U. Wagner, C. Kratky, 1999, Protein science : a publication of the Protein Society.

The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II.

A. Mark, M. Cooper, M. O’Mara, 2011, Biophysical journal.

Imperfect coordination chemistry facilitates metal ion release in the Psa permease.

R. Couñago, A. McEwan, B. Kobe, 2014, Nature chemical biology.

Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection

S. Beatson, A. McEwan, D. Paterson, 2022, mBio.

The antimicrobial potential of cannabidiol

J. Pogliano, N. West, D. Lyras, 2021, Communications Biology.

Synthesis, antibacterial and antifungal activity of new 3-biphenyl-3H-Imidazo[1,2-a]azepin-1-ium bromides.

R. Lesyk, Alysha G. Elliott, J. Zuegg, 2020, European journal of medicinal chemistry.

Metronidazole-triazole conjugates: Activity against Clostridium difficile and parasites

L. Eckmann, C. Tay, Johnny X. Huang, 2015, European journal of medicinal chemistry.

Amino Alcohols as Potential Antibiotic and Antifungal Leads

M. Cooper, A. McCluskey, Alysha G. Elliott, 2022, Molecules.

Vancomycin: ligand recognition, dimerization and super‐complex formation

A. Mark, M. Cooper, M. O’Mara, 2013, The FEBS journal.

Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First In Vivo Experiments

Amy K. Cain, Justin J. Wilson, P. Sadler, 2022, JACS Au.

Metal complexes as a promising source for new antibiotics

Justin J. Wilson, P. Sadler, M. Todd, 2019, Chemical science.

Highly regio- and diastereoselective [3 + 2]-cycloadditions involving indolediones and α,β-disubstituted nitroethylenes.

M. Ganesh, J. Zuegg, M. P. Rao, 2019, Organic & biomolecular chemistry.

Comparison of electrostatic potential around proteins calculated from Amber and AM1 charges: application to mutants of prion protein

Jill E. Gready, Andrey A. Bliznyuk, Johannes Zuegg, 2003 .

α ‐Iodonitroalkenes as Potential Antifungal and Antitubercular Agents

M. Ganesh, J. Zuegg, Gabrielle J. Lowe, 2020 .

Helping Chemists Discover New Antibiotics.

M. Cooper, Alysha G. Elliott, J. Zuegg, 2015, ACS infectious diseases.

Correction: Metal complexes as a promising source for new antibiotics

Justin J. Wilson, P. Sadler, M. Todd, 2020, Chemical science.

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria

D. Paterson, R. Smith, Johnny X. Huang, 2018, Nature Communications.

Synthesis, Antibacterial and Antifungal Activity of New 3-Aryl-5H-pyrrolo[1,2-a]imidazole and 5H-Imidazo[1,2-a]azepine Quaternary Salts

R. Lesyk, Alysha G. Elliott, J. Zuegg, 2021, Molecules.

Multi-Institution Research and Education Collaboration Identifies New Antimicrobial Compounds.

Amelia A. Fuller, Matthew A Cooper, William L Scott, 2020, ACS chemical biology.

Hydroxyl substituted benzoic acid/cinnamic acid derivatives: Tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies.

M. Rafiq, W. M. Hussein, A. Saeed, 2019, Bioorganic & medicinal chemistry letters.

A Subset Screen of the Compounds Australia Scaffold Library Identifies 7-Acylaminodibenzoxazepinones as Potent and Selective Hits for Anti-Giardia Drug Discovery

J. H. Ryan, T. Skinner-Adams, J. Zuegg, 2022, Biomedicines.

Selectivity of lipases : Conformational analysis of suggested intermediates in ester hydrolysis of chiral primary and secondary alcohols

J. Schrag, M. Cygler, J. Zuegg, 1997 .

An evaluation of Minor Groove Binders as anti-fungal and anti-mycobacterial therapeutics.

M. Barrett, F. Brombacher, R. Guler, 2017, European journal of medicinal chemistry.

Rational prioritization strategy allows the design of macrolide derivatives that overcome antibiotic resistance

A. Bashan, A. Yonath, P. Sokkar, 2021, Proceedings of the National Academy of Sciences.

Molecular reasons for lipase-sensitivity against acetaldehyde

K. Faber, J. Zuegg, H. Weber, 1997 .

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

L. Coin, Anna Stincone, K. Francis, 2022, Science Translational Medicine.

Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity

W. Meutermans, A. Lloyd, T. Cheng, 2015, Nature Communications.

An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants

Johnny X. Huang, M. Cooper, M. Butler, 2014, Bioorganic & medicinal chemistry.

A probabilistic measure for alignment-free sequence comparison

Tuan D. Pham, Johannes Zuegg, J. Zuegg, 2004, Bioinform..

Small-Molecule Inhibitors of the SOX18 Transcription Factor.

Y. Gambin, E. Sierecki, P. Koopman, 2017, Cell chemical biology.

Metals to combat antimicrobial resistance

Alysha G. Elliott, J. Zuegg, M. Blaskovich, 2023, Nature Reviews Chemistry.

R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma

E. Pasquier, G. Andelfinger, K. Khosrotehrani, 2019, eLife.

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria

D. Paterson, R. Smith, Johnny X. Huang, 2018, Nature Communications.

Structure aided design of chimeric antibiotics.

Johnny X. Huang, M. Cooper, M. Butler, 2012, Bioorganic & medicinal chemistry letters.

Molecular dynamics simulation of human prion protein including both N-linked oligosaccharides and the GPI anchor.

J. Gready, J. Zuegg, 2000, Glycobiology.

Identification of antitubercular benzothiazinone compounds by ligand-based design.

Johnny X. Huang, M. Cooper, U. Möllmann, 2012, Journal of medicinal chemistry.

Platinum Cyclooctadiene Complexes with Activity against Gram‐positive Bacteria

Amy K. Cain, N. Jung, Lucie Semenec, 2021, ChemMedChem.

An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

Amy K. Cain, Christine J. Boinett, S. Lociuro, 2020, Nature Communications.

How to Stimulate and Facilitate Early Stage Antibiotic Discovery.

M. Cooper, K. Hansford, Alysha G. Elliott, 2020, ACS infectious diseases.

Institutional profile: Community for Open Antimicrobial Drug Discovery – crowdsourcing new antibiotics and antifungals

Matthew A Cooper, Mathilde R. Desselle, Alysha G Elliott, 2017, Future science OA.

Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach

Christopher B. Howard, S. Goodall, Y. Gambin, 2018, mAbs.

Molecular cloning and homology modeling of protocatechuate 3,4-dioxygenase from Pseudomonas marginata.

D. W. Ribbons, H. Schwab, J. Zuegg, 1996, Microbiological research.

On the Prediction of the Enantioselectivity of Candida-Rugosa Lipase by Comparative Molecular-Field Analysis

Helmut Hönig, Kurt Faber, Herfried Griengl, 1994 .

Membrane binding and perturbation studies of the antimicrobial peptides caerin, citropin, and maculatin

C. S. Brian Chia, M. Cooper, J. Bowie, 2011, Biopolymers.

An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

Amy K. Cain, Christine J. Boinett, S. Lociuro, 2020, Nature Communications.

Identification of active-site residues of the pro-metastatic endoglycosidase heparanase.

J. Gready, S. Ohms, M. Hulett, 2000, Biochemistry.

Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach.

A. McEwan, B. Kobe, Johnny X. Huang, 2015, ACS chemical biology.

Molecular dynamics simulations of human prion protein: importance of correct treatment of electrostatic interactions.

J. Gready, J. Zuegg, 1999, Biochemistry.

Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates.

J. Medina-Franco, L. Ruiz-Azuara, J. Zuegg, 2022, Drug discovery today.

Structural model of human IL‐13 defines the spatial interactions with the IL‐13Rα/IL‐4Rα receptor

J. Zuegg, J Zuegg, DC Webb, 2001 .

Antimicrobial screening of a historical collection of over 140 000 small molecules

K. Hansford, Alysha G. Elliott, J. Zuegg, 2021, Mendeleev Communications.