S. Boyd

发表

Fragment-based drug discovery and protein–protein interactions

Andrew P. Turnbull, Björn Walse, Susan M. Boyd, 2014 .

Tailoring Hit Identification and Qualification Methods for Targeting Protein–Protein Interactions

A. Turnbull, S. Boyd, B. Walse, 2017 .

Molecular characterization of macbecin as an Hsp90 inhibitor.

Christine J. Martin, M. Gregory, S. Gaisser, 2008, Journal of medicinal chemistry.

A Novel Pyrazolopyrimidine Ligand of Human PGK1 and Stress Sensor DJ1 Modulates the Shelterin Complex and Telomere Length Regulation

A. Turnbull, A. Bilsland, Katrina Stevenson, 2019, Neoplasia.

Discovery of potent inhibitors of the lysophospholipase autotaxin.

H. Ovaa, A. Turnbull, W. Moolenaar, 2016, Bioorganic & medicinal chemistry letters.

Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors.

Mohammad Nur-E-Alam, Christine J. Martin, Sabine Gaisser, 2008, Journal of medicinal chemistry.

Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta.

V. Grinkevich, A. Turnbull, N. Holliday, 2022, Journal of medicinal chemistry.

Discovery, Development, and SAR of Aminothiazoles as LIMK Inhibitors with Cellular Anti-Invasive Properties.

M. Olson, D. Crighton, S. Boyd, 2015, Journal of medicinal chemistry.

Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival advantage in peritoneal mesothelioma

Alan Bilsland, Jon Roffey, N. Jamieson, 2010, BMC Genomics.

Fragment library design considerations

Andrew P. Turnbull, Björn Walse, Susan M. Boyd, 2012 .

Fragment library design: efficiently hunting drugs in chemical space.

Susan M. Boyd, Gerdien E. de Kloe, S. Boyd, 2010, Drug discovery today. Technologies.

Characterising the geometric diversity of functional groups in chemical databases

Roderick E. Hubbard, Susan M. Boyd, Martin Beverley, 1995, J. Comput. Aided Mol. Des..

By careful selection and experimental design, fragments can provide very useful starting points for medicinal chemistry-driven programmes, leading to tailor-made, selective molecules with highly favourable physico-chemical and ADMET properties

David Bailey, Iwan J. P. de Esch, Susan Boyd, 2008 .