B. Walse

发表

Fragment-based drug discovery and protein–protein interactions

Andrew P. Turnbull, Björn Walse, Susan M. Boyd, 2014 .

The C-Terminal Sequence of Several Human Serine Proteases Encodes Host Defense Functions

A. Schmidtchen, M. Malmsten, M. Mörgelin, 2011, Journal of Innate Immunity.

Proteolysis of Human Thrombin Generates Novel Host Defense Peptides

A. Schmidtchen, M. Malmsten, M. Mörgelin, 2010, PLoS pathogens.

Tailoring Hit Identification and Qualification Methods for Targeting Protein–Protein Interactions

A. Turnbull, S. Boyd, B. Walse, 2017 .

Transferred nuclear Overhauser effect spectroscopy study of a peptide from the PapG pilus subunit bound by the Escherichia coli PapD chaperone

J. Pinkner, S. Hultgren, J. Kihlberg, 1997, FEBS letters.

Crystal structures of the Bacillus subtilis prophage lytic cassette proteins XepA and YomS

E. Pohl, S. Al-Karadaghi, M. Plotka, 2019, Acta crystallographica. Section D, Structural biology.

The interaction properties of costimulatory molecules revisited.

Andrea Iaboni, Simon J Davis, David I Stuart, 2002, Immunity.

Structural Evidence for Zinc and Peptide Dependence in Superantigen-Major Histocompatibility Complex Class II Interaction

B. Walse, 2007 .

Molecular Characterization of a Novel Lytic Enzyme LysC from Clostridium intestinale URNW and Its Antibacterial Activity Mediated by Positively Charged N-Terminal Extension

S. Al-Karadaghi, M. Plotka, A. Kaczorowska, 2020, International journal of molecular sciences.

Building blocks for glycopeptide synthesis: glycosylation of 3-mercaptopropionic acid and Fmoc amino acids with unprotected carboxyl groups

J. Kihlberg, M. Elofsson, B. Walse, 1991 .

Solid-phase synthesis and conformational studies of helper T cell immunogenic peptides that carry carbohydrate haptens linked to serine.

J. Kihlberg, M. Elofsson, B. Walse, 2009, International journal of peptide and protein research.

Antimicrobial activity of peptides derived from human ß‐amyloid precursor protein

A. Schmidtchen, M. Malmsten, M. Mörgelin, 2012, Journal of peptide science : an official publication of the European Peptide Society.

The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity

D. Logan, S. Dillon, M. Maurer, 2022, Nature Communications.

Cancer Differentiating Agent Hexamethylene Bisacetamide Inhibits BET Bromodomain Proteins.

D. Logan, J. Nilsson, L. Nilsson, 2016, Cancer research.

Collagen VI Contains Multiple Host Defense Peptides with Potent In Vivo Activity

A. Schmidtchen, M. Mörgelin, A. Strömstedt, 2018, The Journal of Immunology.

Development of Interleukin-1 Receptor Antagonist Mutants with Enhanced Antagonistic Activity In Vitro and Improved Therapeutic Efficacy in Collagen-Induced Arthritis

L. Joosten, W. B. van den Berg, M. Andersson, 2008, Journal of immunotoxicology.

Interplay Between Superantigens and Immunoreceptors

B. Walse, G. Forsberg, K. Petersson, 2004, Scandinavian journal of immunology.

Exploitation of DHODH and p53 activation as therapeutic targets - a case study in polypharmacology

Srinivasaraghavan, Gergana Popova, C. Verma, 2020 .

Glycosylated peptide hormones: pharmacological properties and conformational studies of analogues of [1-desamino,8-D-arginine]vasopressin.

J. Kihlberg, T. Drakenberg, B. Walse, 1995, Journal of medicinal chemistry.

Crystal structures of the Chromobacterium violaceumω‐transaminase reveal major structural rearrangements upon binding of coenzyme PLP

D. Logan, Per Berglund, B. Walse, 2012, The FEBS journal.

Staphylococcal Enterotoxin H Induces Vα-Specific Expansion of T Cells

B. Walse, G. Forsberg, H. Pettersson, 2003, The Journal of Immunology.

Glycosylation of C-unprotected 3-mercaptopropionic acid and Fmoc amino acids: Application to the synthesis of glycosylated derivatives of a helper T-cell-stimulating peptide

J. Kihlberg, M. Elofsson, B. Walse, 1993 .

Identification of conformational epitopes for human IgG on Chemotaxis inhibitory protein of Staphylococcus aureus

M. Hijnen, J. V. van Strijp, M. Ohlin, 2009, BMC Immunology.

Cutting Edge: Evidence of Direct TCR α-Chain Interaction with Superantigen1

B. Jakobsen, K. Lindkvist-Petersson, B. Walse, 2007, The Journal of Immunology.

Inhibition of Human DHODH by 4‐Hydroxycoumarins, Fenamic Acids, and N‐(Alkylcarbonyl)anthranilic Acids Identified by Structure‐Guided Fragment Selection

S. Al-Karadaghi, B. Walse, B. Svensson, 2010, ChemMedChem.

Insight into the dimer dissociation process of the Chromobacterium violaceum (S)-selective amine transaminase

D. Logan, Per Berglund, B. Walse, 2019, Scientific Reports.

Conformation of desmopressin, an analogue of the peptide hormone vasopressin, in aqueous solution as determined by NMR spectroscopy.

J. Kihlberg, T. Drakenberg, B. Walse, 1998, European journal of biochemistry.

Transaminase‐Catalyzed Racemization with Potential for Dynamic Kinetic Resolutions

D. Logan, Per Berglund, B. Walse, 2018, ChemCatChem.

Binding of peptides in solution by the Escherichia coli chaperone PapD as revealed using an inhibition ELISA and NMR spectroscopy.

J. Pinkner, S. Hultgren, J. Kihlberg, 1998, Bioorganic & medicinal chemistry.

Intact Protein Analysis at 21 Tesla and X-Ray Crystallography Define Structural Differences in Single Amino Acid Variants of Human Mitochondrial Branched-Chain Amino Acid Aminotransferase 2 (BCAT2)

C. Nilsson, Lissa C. Anderson, B. Walse, 2017, Journal of The American Society for Mass Spectrometry.

Benzimidazole-galactosides bind selectively to the Galectin-8 N-Terminal domain: Structure-based design and optimisation.

M. Anderluh, C. Diehl, T. Tomašič, 2021, European journal of medicinal chemistry.

Rational design of antimicrobial C3a analogues with enhanced effects against Staphylococci using an integrated structure and function-based approach.

A. Schmidtchen, M. Malmsten, Mukesh Pasupuleti, 2008, Biochemistry.

Crystal structure of a SEA variant in complex with MHC class II reveals the ability of SEA to crosslink MHC molecules.

M. Thunnissen, B. Walse, G. Forsberg, 2002, Structure.

Crystal structure of a superantigen bound to MHC class II displays zinc and peptide dependence

A. Liljas, B. Walse, M. Håkansson, 2001, The EMBO journal.

Structural features of a polypeptide carrier promoting secretion of a β‐lactamase fusion protein in yeast

H. Vihinen, M. Simonen, N. Kalkkinen, 1995, Yeast.

Going to extremes - a metagenomic journey into the dark matter of life.

Sigmar K. Stefánsson, J. Söding, E. Karlsson, 2021, FEMS microbiology letters.

Solid-phase synthesis and conformational studies of glycosylated derivatives of helper-T-cell immunogenic peptides from hen-egg lysozyme.

J. Kihlberg, M. Elofsson, B. Walse, 1993, Carbohydrate research.

Directed evolution of chemotaxis inhibitory protein of Staphylococcus aureus generates biologically functional variants with reduced interaction with human antibodies.

S. Lindman, K. Haraldsson, J. V. van Strijp, 2010, Protein engineering, design & selection : PEDS.

Crystal structure of a soluble CD28-Fab complex

D. Stuart, R. Esnouf, T. Hanke, 2005, Nature Immunology.

The structures of human dihydroorotate dehydrogenase with and without inhibitor reveal conformational flexibility in the inhibitor and substrate binding sites.

S. Al-Karadaghi, B. Walse, B. Svensson, 2008, Biochemistry.

Specific Expansion of T Cells α Staphylococcal Enterotoxin H Induces V

Björn Walse, Göran Forsberg, Karin Petersson, 2013 .

Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

Gergana Popova, K. Larsson, A. Thompson, 2018, Nature Communications.

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

Gergana Popova, K. Larsson, A. Thompson, 2018, Nature Communications.

Midkine and Pleiotrophin Have Bactericidal Properties

A. Schmidtchen, M. Malmsten, R. Palmer, 2010, The Journal of Biological Chemistry.

Structural basis for carbohydrate-binding specificity--a comparative assessment of two engineered carbohydrate-binding modules.

D. Logan, M. Ohlin, B. Walse, 2012, Glycobiology.

Fragment library design considerations

Andrew P. Turnbull, Björn Walse, Susan M. Boyd, 2012 .

Structure of a cyclic peptide with a catalytic triad, determined by computer simulation and NMR spectroscopy

Björn Walse, Magnus Ullner, Christer Lindbladh, 1996, J. Comput. Aided Mol. Des..

Identification of Protein-Protein Interfaces Implicated in CD80-CD28 Costimulatory Signaling

K. Bennett, M. Kussmann, P. Roepstorff, 2004, The Journal of Immunology.

Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology

Gergana Popova, D. Lane, C. Verma, 2020, The Journal of Biological Chemistry.

Synthesis and conformational studies of peptides fromE. coli pilus proteins recognized by the chaperone PapD

J. Kihlberg, T. Drakenberg, B. Walse, 1996, Letters in Peptide Science.

Preservation of Antimicrobial Properties of Complement Peptide C3a, from Invertebrates to Humans*

A. Schmidtchen, M. Malmsten, M. Mörgelin, 2007, Journal of Biological Chemistry.

Antimicrobial peptides derived from growth factors

Björn Walse, Martin Malmsten, Artur Schmidtchen, 2007, Growth factors.

Identification of the antigenic epitopes in staphylococcal enterotoxins A and E and design of a superantigen for human cancer therapy.

P. Antonsson, B. Walse, G. Forsberg, 2003, Journal of molecular biology.

Discovery of Selective Small-Molecule CD80 Inhibitors

M. Åkesson, K. Uvebrant, P. Björk, 2007, Journal of biomolecular screening.

De Novo Fragment Design for Drug Discovery and Chemical Biology.

Petra Schneider, Gisbert Schneider, Daniel Reker, 2015, Angewandte Chemie.

Virtual Screening and Design with Machine Intelligence Applied to Pim‐1 Kinase Inhibitors

Gisbert Schneider, Bo Svensson, Petra Schneider, 2020, Molecular informatics.

Specific Expansion of T Cells α Staphylococcal Enterotoxin H Induces V

B. Walse, G. Forsberg, H. Pettersson, 2013 .

Cutting edge: Evidence of direct TCR alpha-chain interaction with superantigen.

B. Jakobsen, K. Lindkvist-Petersson, B. Walse, 2007, Journal of immunology.

Inhibition of Human DHODH by 4‐Hydroxycoumarins, Fenamic Acids, and N‐(Alkylcarbonyl)anthranilic Acids Identified by Structure‐Guided Fragment Selection

S. Al-Karadaghi, B. Walse, B. Svensson, 2010, ChemMedChem.