D. Arnaiz

发表

Novel Small Molecule Inhibitors of 3-Phosphoinositide-dependent Kinase-1*

Marc Adler, M. Adler, M. Whitlow, 2005, Journal of Biological Chemistry.

Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 2: optimization of BX-517.

M. Adler, M. Whitlow, R. Feldman, 2007, Bioorganic & medicinal chemistry letters.

Potent Triazolothione Inhibitor of Heat‐Shock Protein‐90

M. Adler, M. Whitlow, R. Feldman, 2009, Chemical biology & drug design.

249 Novel small molecule inhibitors of 3′-phosphoinositide-dependent kinase-1 (PDK-1)

R. Feldman, B. Alicke, M. Polokoff, 2004 .

CCR5 receptor antagonists: discovery and SAR study of guanylhydrazone derivatives.

D. Davey, G. Phillips, J. Onuffer, 2007, Bioorganic & medicinal chemistry letters.

The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex.

M. Adler, M. Whitlow, E. Zhang, 2006, Bioorganic & Medicinal Chemistry Letters.

Synthesis of 13C3,15N4-labeled factor Xa inhibitor

D. Arnaiz, J. Dallas, W. Guilford, 2001 .

Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors.

Bin Ye, David Light, Marc Adler, 2007, Journal of medicinal chemistry.

Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin.

M. Whitlow, D. Davey, M. Morrissey, 1999, Acta crystallographica. Section D, Biological crystallography.

Design, synthesis, and in vitro biological activity of benzimidazole based factor Xa inhibitors.

M. Whitlow, M. Morrissey, S. Sakata, 2000, Bioorganic & medicinal chemistry letters.

Design, synthesis, and in vitro biological activity of indole-based factor Xa inhibitors.

D. Arnaiz, L. Trinh, K. Shaw, 2000, Bioorganic & medicinal chemistry letters.

Conformations of trypsin-bound amidine inhibitors of blood coagulant factor Xa by double REDOR NMR and MD simulations.

M. Whitlow, M. McCarrick, J. Schaefer, 1999, Journal of medicinal chemistry.

Formation of Carbon-Carbon Bonds via Quinone Methide-Initiated Cyclization Reactions

J. Rainier, D. Arnaiz, Wenjin Yang, 1994 .

Formation of Carbon-Carbon Bonds via Quinone Methide-Initiated Cyclization Reactions.

J. Rainier, D. Arnaiz, Wenjin Yang, 1995 .

Formal [3+2]cycloaddition of benzylic cations with alkenes

D. Arnaiz, S. R. Angle, 1992 .

Synthesis of dihydro-1H-indenes via a formal 3 + 2 cycloaddition of para-quinone methides and styrenes

D. Arnaiz, S. R. Angle, 1990 .

Stereoselective synthesis of substituted pipecolic acids

D. Arnaiz, S. R. Angle, 1989 .

Synthesis of 1,2-dihydronaphthalenes and spiro[4.5]-deca-3,6,9-trien-8-ones from benzylic alcohols

D. Arnaiz, S. R. Angle, 1991 .

Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: design, synthesis and biological activity.

M. Adler, M. Whitlow, R. Feldman, 2007, Bioorganic & medicinal chemistry letters.

Derives benzimidazole substitues par un naphtyle comme anticoagulants

S. Sakata, D. Arnaiz, K. Shaw, 1996 .

Human factor Xa bound amidine inhibitor conformation by double rotational-echo double resonance nuclear magnetic resonance and molecular dynamics simulations.

M. Adler, M. McCarrick, J. Schaefer, 2003, Journal of medicinal chemistry.

Conformation of a bound inhibitor of blood coagulant factor Xa.

M. Adler, A. Mehta, J. Schaefer, 2003, Biochemistry.

Design, synthesis, and activity of 2-imidazol-1-ylpyrimidine derived inducible nitric oxide synthase dimerization inhibitors.

M. Adler, M. Whitlow, M. Ohlmeyer, 2007, Journal of medicinal chemistry.

Design, synthesis, and in vitro biological activity of indole-based factor Xa inhibitors.

M. Whitlow, D. Arnaiz, L. Trinh, 2000, Bioorganic & medicinal chemistry letters.

Formal (3 + 2)Cycloaddition of Benzylic Cations with Alkenes.

D. Arnaiz, S. R. Angle, 1993 .