M. Bobko

发表

Structure-based design of potent and selective 3-phosphoinositide-dependent kinase-1 (PDK1) inhibitors.

S. Rabindran, N. Campobasso, V. Sudakin, 2011, Journal of medicinal chemistry.

Rapid synthesis of diversely functionalized 3,4,7-trisubstituted indoles

T. Gallagher, J. Axten, Seth W. Grant, 2011 .

Synthesis, characterization, and conformational analysis of the D/L-Tic7 stereoisomers of the bradykinin receptor antagonist D-Arg0[Hyp3,Thi5,D-Tic7,Oic8]bradykinin.

J. Salvino, R. Dolle, B. Douty, 1994, Biochemistry.

Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk).

B. Tomczuk, R. DesJarlais, D. Ryan, 2008, Bioorganic & medicinal chemistry letters.

5,7-Dimethoxy-3-(4-pyridinyl)quinoline is a potent and selective inhibitor of human vascular beta-type platelet-derived growth factor receptor tyrosine kinase.

R. Dolle, M. Bobko, D. Sawutz, 1994, Journal of medicinal chemistry.

ISOLATION AND STRUCTURE ELUCIDATION OF TWO NEW CALPAIN INHIBITORS FROMStreptomyces

J. Brownell, A. Rodger, A. Gillum, 2006 .

Isolation and structure elucidation of two new calpain inhibitors from Streptomyces griseus.

J. Brownell, A. Gillum, M. Bobko, 1994, The Journal of antibiotics.

CD45 protein tyrosine phosphatase: Determination of minimal peptide length for substrate recognition and synthesis of some tyrosine-based electrophiles as potential active-site directed irreversible inhibitors

A. Saha, R. Dolle, M. Bobko, 1995 .

Discovery and SAR of novel Naphthyridines as potent inhibitors of spleen tyrosine kinase (SYK).

Renee L DesJarlais, Mark R Player, R. DesJarlais, 2003, Bioorganic & medicinal chemistry letters.

Optimization of the 4-aryl group of 4-aryl-pyridine glucagon antagonists: development of an efficient, alternative synthesis.

J. Livingston, J. Jones, M. Bobko, 2002, Bioorganic & medicinal chemistry letters.

Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach.

J. S. Johnson, H. Wild, D. Rogers, 2001, Bioorganic & medicinal chemistry letters.

Structure determination, pharmacological evaluation, and structure-activity studies of a new cyclic peptide substance P antagonist containing the new amino acid 3-prenyl-beta-hydroxytyrosine, isolated from Aspergillus flavipes.

C. Barrow, M. Bobko, M. Doleman, 1994, Journal of medicinal chemistry.

Discovery of a new class of p38 kinase inhibitors.

J. S. Johnson, S. Wilhelm, W. Scott, 2000, Bioorganic & medicinal chemistry letters.

Solid-phase synthesis of a library of piperazinediones and diazepinediones via Kaiser oxime resin.

M. Bobko, W. Lee, R. Smith, 1998, Bioorganic & medicinal chemistry letters.

Expeditious Synthesis of a Potent Allosteric HIV-1 Integrase Inhibitor GSK3839919A

Jennifer M. Elward, Q. Su, M. Bobko, 2023, Organic Process Research & Development.

Analogues of human parathyroid hormone (1-31)NH(2): further evaluation of the effect of conformational constraint on biological activity.

I. Morize, R. Labaudinière, S. Condon, 2002, Bioorganic & medicinal chemistry.

Synthesis of 2,5-disubstituted-3-cyanoindoles

Leanna E. Shuster, A. Kaura, K. Evans, 2012 .

Acylprolinamides: a new class of peptide deformylase inhibitors with in vivo antibacterial activity.

N. Campobasso, J. Axten, Seth W. Grant, 2012, Bioorganic & medicinal chemistry letters.