M. Barker

发表

4-Phenyl-7-azaindoles as potent, selective and bioavailable IKK2 inhibitors demonstrating good in vivo efficacy.

P. Bamborough, W. Rumsey, C. Chung, 2012, Bioorganic & medicinal chemistry letters.

Preparation of enantiomerically pure phosphine oxides by nucleophilic displacement chemistry using oxazaphospholidines

J. V. Carey, John M. Brown, M. Barker, 1993 .

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

David M. Wilson, G. Drewes, D. Eberhard, 2015, Nature chemical biology.

4-Phenyl-7-azaindoles as potent and selective IKK2 inhibitors.

P. Bamborough, J. Liddle, M. Morse, 2009, Bioorganic & medicinal chemistry letters.

Kinetic resolution of racemic pyrrolidine-2,5-diones using chiral oxazaborolidine catalysts.

M. Barker, B. J. Marsh, Simon Jones, 2008, Chemical communications.

The solid phase synthesis of a series of tri-substituted hydantoin ligands for the somatostatin SST5 receptor.

J. Scicinski, M. Barker, E. Jarvie, 1998, Bioorganic & medicinal chemistry letters.

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives.

David M. Wilson, Melanie V. Leveridge, G. Drewes, 2016, Journal of medicinal chemistry.

Enantioselective catalytic desymmetrization of maleimides by temporary removal of an internal mirror plane and stereoablative over-reduction: synthesis of (R)-pyrrolam A.

H. Adams, M. Barker, B. J. Marsh, 2014, Organic letters.

Optimisation of a novel series of potent and orally bioavailable azanaphthyridine SYK inhibitors.

David M. Wilson, J. Liddle, D. Lugo, 2016, Bioorganic & medicinal chemistry letters.

Configuration of a High-Content Imaging Platform for Hit Identification and Pharmacological Assessment of JMJD3 Demethylase Enzyme Inhibitors

Melanie Leveridge, Emma Jones, John Liddle, 2012, Journal of biomolecular screening.

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives.

Douglas W. Thomson, David M. Wilson, Melanie V. Leveridge, 2016, Journal of medicinal chemistry.

Discovery of potent and selective Spleen Tyrosine Kinase inhibitors for the topical treatment of inflammatory skin disease.

David M. Wilson, J. Liddle, D. Somers, 2018, Bioorganic & medicinal chemistry letters.

Quinolines as a novel structural class of potent and selective PDE4 inhibitors. Optimisation for inhaled administration.

Tony W Dean, Michael D. Woodrow, D. Somers, 2009, Bioorganic & medicinal chemistry letters.

The crucial role of the nitrogen substituent in the desymmetrisation of cyclic meso-imides using B-Me and B-OMe oxazaborolidine catalysts

M. Barker, B. J. Marsh, R. Dixon, 2006 .

The Crucial Role of the Nitrogen Substituent in the Desymmetrization of Cyclic meso-Imides Using B-Me and B-O-Me Oxazaborolidine Catalysts.

M. Barker, B. J. Marsh, R. Dixon, 2007 .

Investigating the effects of the core nitrogen atom configuration on the thermodynamic solubility of 6,5-bicyclic heterocycles.

M. Barker, N. Tomkinson, Sophie M. Bertrand, 2020, Bioorganic & medicinal chemistry letters.