C. Tam

发表

Mutation of the phospholipase catalytic domain of the Pseudomonas aeruginosa cytotoxin ExoU abolishes colonization promoting activity and reduces corneal disease severity.

W. Y. Li, D. Evans, C. Tam, 2007, Experimental eye research.

Clearance of Pseudomonas aeruginosa from a Healthy Ocular Surface Involves Surfactant Protein D and Is Compromised by Bacterial Elastase in a Murine Null-Infection Model

D. Kowbel, James J. Mun, David J. Evans, 2009, Infection and Immunity.

Role of Defensins in Corneal Epithelial Barrier Function against Pseudomonas aeruginosa Traversal

David J. Evans, S. Fleiszig, S. Heimer, 2010, Infection and Immunity.

Simultaneous Control of Infection and Inflammation by Keratin-Derived Antibacterial Peptides (KAMPs) Targeting TLRs and Co-Receptors

Yan Sun, C. Tam, J. Chan, 2021, bioRxiv.

Modulation of epithelial immunity by mucosal fluid

James J. Mun, David J. Evans, S. Fleiszig, 2011, Scientific reports.

Adenylate cyclase activity of Pseudomonas aeruginosa ExoY can mediate bleb-niche formation in epithelial cells and contributes to virulence.

James J. Mun, David J. Evans, S. Fleiszig, 2011, Microbial pathogenesis.

The impact of inoculation parameters on the pathogenesis of contact lens-related infectious keratitis.

James J. Mun, David J. Evans, S. Fleiszig, 2010, Investigative ophthalmology & visual science.

Factors impacting corneal epithelial barrier function against Pseudomonas aeruginosa traversal.

James J. Mun, David J. Evans, S. Fleiszig, 2011, Investigative ophthalmology & visual science.

Association between cytotoxic and invasive Pseudomonas aeruginosa and clinical outcomes in bacterial keratitis.

M. Srinivasan, S. Fleiszig, T. Lietman, 2013, JAMA ophthalmology.

Expression of surfactant protein D in human corneal epithelial cells is upregulated by Pseudomonas aeruginosa.

R. Ramphal, David J. Evans, Amrisha Verma, 2008, FEMS immunology and medical microbiology.

Contributions of MyD 88-Dependent Receptors and CD 11 c-Positive Cells to Corneal Epithelial Barrier Function Against Pseudomonas Aeruginosa

David J. Evans, S. Fleiszig, C. Tam, 2018 .

Contributions of MyD88-dependent receptors and CD11c-positive cells to corneal epithelial barrier function against Pseudomonas aeruginosa

David J. Evans, S. Fleiszig, C. Tam, 2017, Scientific Reports.

The Salmonella enterica Serovar Typhi Type IVB Self-Association Pili Are Detached from the Bacterial Cell by the PilV Minor Pilus Proteins

C. Tam, J. Hackett, C. Morris, 2006, Infection and Immunity.

Salmonella enterica Serovar Paratyphi C Carries an Inactive Shufflon

C. Tam, J. Hackett, C. Morris, 2004, Infection and Immunity.

Salmonella enterica serovar Dublin strains which are Vi antigen-positive use type IVB pili for bacterial self-association and human intestinal cell entry.

T. Wallis, C. Tam, J. Hackett, 2003, Microbial pathogenesis.

A novel murine model for contact lens wear reveals clandestine IL-1R dependent corneal parainflammation and susceptibility to microbial keratitis upon inoculation with Pseudomonas aeruginosa.

James J. Mun, David J. Evans, S. Fleiszig, 2019, The ocular surface.

Rate of Inversion of the Salmonella enterica Shufflon Regulates Expression of Invertible DNA

C. Tam, J. Hackett, C. Morris, 2005, Infection and Immunity.

Impact of topical corticosteroid pretreatment on susceptibility of the injured murine cornea to Pseudomonas aeruginosa colonization and infection

David J. Evans, S. Fleiszig, C. Tam, 2019, Experimental eye research.

Cytokeratins mediate epithelial innate defense through their antimicrobial properties.

James J. Mun, David J. Evans, S. Fleiszig, 2012, The Journal of clinical investigation.

Topical tacrolimus νanocapsules eye drops for therapeutic effect enhancement in both anterior and posterior ocular inflammation models.

S. Benita, Yan Sun, C. Tam, 2021, Journal of controlled release : official journal of the Controlled Release Society.

Traversal of multilayered corneal epithelia by cytotoxic Pseudomonas aeruginosa requires the phospholipase domain of exoU.

David J. Evans, S. Fleiszig, C. Tam, 2012, Investigative ophthalmology & visual science.

Human Tear Fluid Reduces Culturability of Contact Lens-Associated Pseudomonas aeruginosa Biofilms but Induces Expression of the Virulence-Associated Type III Secretion System.

David J. Evans, S. Fleiszig, C. Tam, 2017, The ocular surface.

MicroRNA-762 Is Upregulated in Human Corneal Epithelial Cells in Response to Tear Fluid and Pseudomonas aeruginosa Antigens and Negatively Regulates the Expression of Host Defense Genes Encoding RNase7 and ST2

James J. Mun, David J. Evans, S. Fleiszig, 2013, PloS one.

Membrane-Active Epithelial Keratin 6A Fragments (KAMPs) Are Unique Human Antimicrobial Peptides with a Non-αβ Structure

Guangshun Wang, C. Tam, Judy Lee, 2016, Front. Microbiol..

3D Quantitative Imaging of Unprocessed Live Tissue Reveals Epithelial Defense against Bacterial Adhesion and Subsequent Traversal Requires MyD88

James J. Mun, David J. Evans, S. Fleiszig, 2011, PloS one.

Simultaneous control of infection and inflammation with keratin-derived antibacterial peptides targeting TLRs and co-receptors

C. Tam, Yan Sun, J. Chan, 2023, Science Translational Medicine.

Contributions of MyD88-Dependent Receptors and CD11c- Contributions of MyD88-Dependent Receptors and CD11c-Positive Cells to Corneal Epithelial Barrier Function Against Positive Cells to Corneal Epithelial Barrier Function Against Pseudomonas Aeruginosa Pseudomonas Aeruginosa

S. Fleiszig, C. Tam, M. Stern, 2020 .

Human Tear Fluid Reduces Culturability of Contact Lens-Associated Pseudomonas aeruginosa Biofilms but Induces Expression of the Virulence-Associated Type III Secretion System.

S. Fleiszig, C. Tam, Yvonne T Wu, 2017, The ocular surface.

Cytokeratins mediate epithelial innate defense through their antimicrobial properties.

James J. Mun, S. Fleiszig, C. Tam, 2012, The Journal of clinical investigation.

Efficacy and Structure-Activity of Keratin-Derived Antimicrobial Peptides (kDAMPs): A Novel Role for Intermediate Filament Proteins in Corneal Innate Defense

James J. Mun, S. Fleiszig, C. Tam, 2012 .

Role of Defensins in Corneal Epithelial Barrier Function against Pseudomonas aeruginosa Traversal

S. Fleiszig, S. Heimer, C. Tam, 2010, Infection and Immunity.

Adenylate cyclase activity of Pseudomonas aeruginosa ExoY can mediate bleb-niche formation in epithelial cells and contributes to virulence.

James J. Mun, S. Fleiszig, J. Barbieri, 2011, Microbial pathogenesis.