Sveva Pelliccia

发表

Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity.

Ettore Novellino, Luciana Marinelli, Sandro Cosconati, 2017, Journal of medicinal chemistry.

Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities

A. Coluccia, R. Silvestri, G. La Regina, 2017, Journal of enzyme inhibition and medicinal chemistry.

Visible light photocatalysis in the late-stage functionalization of pharmaceutically relevant compounds.

E. Novellino, G. Tron, M. Giustiniano, 2020, Chemical Society reviews.

Selenotriapine – An isostere of the most studied thiosemicarbazone with pronounced pro-apoptotic activity, low toxicity and ability to challenge phenotype reprogramming of 3-D mammary adenocarcinoma tumors

R. Silvestri, G. La Regina, V. Jovanović, 2017, Arabian Journal of Chemistry.

Bio-Inspired Dual Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives.

E. Novellino, B. Pagano, Jussara Amato, 2020, Journal of medicinal chemistry.

Aryl azides as forgotten electrophiles in the Van Leusen reaction: a multicomponent transformation affording 4-tosyl-1-arylimidazoles.

E. Novellino, F. Meneghetti, G. Tron, 2019, The Journal of organic chemistry.

Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors.

C. Supuran, A. Coluccia, D. Vullo, 2015, Journal of medicinal chemistry.

Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors.

Y. Ni, E. Novellino, B. Maresca, 2013, Journal of medicinal chemistry.

Enriching the Arsenal of Pharmacological Tools against MICAL2

F. Da Settimo, S. Taliani, D. Brancaccio, 2021, Molecules.

Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors

E. Novellino, A. Mollica, R. Silvestri, 2017, Journal of enzyme inhibition and medicinal chemistry.

Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route

M. Brindisi, V. Summa, P. Storici, 2022, European Journal of Medicinal Chemistry.

Arylsulfone-based HIV-1 non-nucleoside reverse transcriptase inhibitors.

A. Coluccia, A. Brancale, R. Silvestri, 2013, Future medicinal chemistry.

Interrupted Ugi and Passerini Reactions: An Underexplored Treasure Island

E. Novellino, A. Basso, G. Tron, 2018, Synthesis.

Non-hydrolytic chemoselective cleavage of Ugi tertiary amides: A mild access to N-substituted α-amino acid amides

E. Novellino, G. Tron, M. Giustiniano, 2018 .

Amphoteric 2-(sulfonylamino)benzaldehydes, secondary amines and isocyanides in the multicomponent synthesis of elusive N-alkyl-2,3-diaminoindoles

E. Novellino, F. Meneghetti, G. Tron, 2017 .

A fast route for the synthesis of tetrazolyl oximes by a novel multicomponent reaction between Z-chlorooximes, isocyanides and trimethylsilyl azide

E. Novellino, Michele Pavone, B. Pagano, 2017 .

Exploiting the Nucleophilicity of the Nitrogen Atom of Imidazoles: One-Pot Three-Component Synthesis of Imidazo-Pyrazines

E. Novellino, F. Meneghetti, G. Tron, 2019, Molecules.

Photocatalytic Isocyanide-based Multicomponent Domino Cascade Towards the Stereoselective Formation of Iminofurans.

E. Novellino, A. Massarotti, G. Tron, 2019, The Journal of organic chemistry.

Design, synthesis, and biological evaluation of 1-phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as new glycogen synthase kinase-3β inhibitors.

E. Novellino, A. Coluccia, A. Brancale, 2013, Journal of medicinal chemistry.

New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer.

E. Novellino, L. Di Marcotullio, C. Martini, 2015, Journal of medicinal chemistry.

New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer.

Ettore Novellino, Andrea Brancale, Ruoli Bai, 2014, Journal of medicinal chemistry.

Continuous-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds

S. Collina, M. Brindisi, Sveva Pelliccia, 2023, ACS Medicinal Chemistry Letters.

Indolylarylsulfones carrying a heterocyclic tail as very potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors.

E. Novellino, A. Coluccia, A. Brancale, 2014, Journal of Medicinal Chemistry.

New indolylarylsulfones as highly potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors.

E. Novellino, B. Clotet, A. Coluccia, 2014, European journal of medicinal chemistry.

A Successful Replacement of Phenols with Isocyanides in the Bargellini Reaction: Synthesis of 3-Carboxamido-Isobutyric Acids.

E. Novellino, G. Tron, M. Giustiniano, 2016, The Journal of organic chemistry.

SARS-CoV-2 Entry Inhibitors: Small Molecules and Peptides Targeting Virus or Host Cells

V. Summa, A. Beccari, Sveva Pelliccia, 2020, International journal of molecular sciences.

α-Amino Acids as Synthons in the Ugi-5-Centers-4-Components Reaction: Chemistry and Applications

Ettore Novellino, Gian Cesare Tron, Sveva Pelliccia, 2019, Symmetry.

New 1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides inhibit hepatitis C virus replication via suppression of cyclooxygenase-2.

A. Coluccia, C. Zamperini, M. Botta, 2015, European journal of medicinal chemistry.

Pro-apoptotic and pro-differentiation induction by 8-quinolinecarboxaldehyde selenosemicarbazone and its Co(III) complex in human cancer cell lines

R. Silvestri, C. Muller, D. Stanković, 2016 .

Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination

M. Brindisi, V. Summa, P. Storici, 2023, European Journal of Medicinal Chemistry.

Rejuvenating the [1, 2, 3]-triazolo [1,5-a]quinoxalin-4(5H)-one scaffold: Synthesis and derivatization in a sustainable guise and preliminary antimicrobial evaluation

M. Brindisi, V. Summa, E. Buommino, 2023, Frontiers in Chemistry.

New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer.

E. Novellino, L. Di Marcotullio, A. Brancale, 2014, Journal of medicinal chemistry.

Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors.

Y. Ni, E. Novellino, B. Maresca, 2013, Journal of medicinal chemistry.

3-Aroyl-1-arylpyrroles: a New Class of Potent Inhibitors of Tubulin Polymerization.

E. Novellino, R. Silvestri, E. Hamel, 2014 .