D B Mendel

Neuraminidase Inhibitors as Anti-Influenza Virus Agents

Xiaowu Chen, D. Mendel, C U Kim, 1999, Antiviral chemistry & chemotherapy.

Structure-activity relationship studies of novel carbocyclic influenza neuraminidase inhibitors.

W G Laver, M A Williams, R C Stevens, 1998, Journal of medicinal chemistry.

Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity.

W G Laver, M A Williams, R C Stevens, 1997, Journal of the American Chemical Society.

The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo.

J. Oxford, F. Hayden, J S Oxford, 2002, Antiviral research.

A new series of C3-aza carbocyclic influenza neuraminidase inhibitors: synthesis and inhibitory activity.

W G Laver, C U Kim, X Chen, 1998, Bioorganic & medicinal chemistry letters.

Identity of 4a-carbinolamine dehydratase, a component of the phenylalanine hydroxylation system, and DCoH, a transregulator of homeodomain proteins.

G. Crabtree, S. Milstien, S. Kaufman, 1992, Proceedings of the National Academy of Sciences of the United States of America.

HNF-1 shares three sequence motifs with the POU domain proteins and is identical to LF-B1 and APF.

G. Crabtree, G. Courtois, C. Kuo, 1990, Genes & development.

Carbocyclic influenza neuraminidase inhibitors possessing a C3-cyclic amine side chain: synthesis and inhibitory activity.

B. Graves, X. Chen, D. Mendel, 2000, Bioorganic & medicinal chemistry letters.

Inhibition of the high affinity Fc receptor (Fc gamma RI) on human monocytes by porphyrin photosensitization is highly specific and mediated by the generation of superoxide radicals.

C. Elmets, H. Mukhtar, M. Athar, 1989, The Journal of biological chemistry.