Jean-Philippe Pin

发表

N-{4-Chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide (CPPHA) Acts through a Novel Site as a Positive Allosteric Modulator of Group 1 Metabotropic Glutamate Receptors

P. Jeffrey Conn, J. Pin, P. Conn, 2008, Molecular Pharmacology.

Sequential Inter- and Intrasubunit Rearrangements During Activation of Dimeric Metabotropic Glutamate Receptor 1

Carsten Hoffmann, L. Prézeau, U. Zabel, 2012, Science Signaling.

A Single Subunit (GB2) Is Required for G-protein Activation by the Heterodimeric GABAB Receptor*

Julie Perroy, L. Prézeau, L. Fagni, 2002, The Journal of Biological Chemistry.

Closed state of both binding domains of homodimeric mGlu receptors is required for full activity

L. Prézeau, J. Pin, J. Kniazeff, 2004, Nature Structural &Molecular Biology.

Common Structural Requirements for Heptahelical Domain Function in Class A and Class C G Protein-coupled Receptors*

Gilles Labesse, G. Labesse, L. Prézeau, 2007, Journal of Biological Chemistry.

Multicolor time‐resolved Förster resonance energy transfer microscopy reveals the impact of GPCR oligomerization on internalization processes

Eric Trinquet, Orestis Faklaris, J. Pin, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The Metabotropic Glutamate Receptor mGlu7 Activates Phospholipase C, Translocates Munc-13-1 Protein, and Potentiates Glutamate Release at Cerebrocortical Nerve Terminals*

Francisco Ciruela, F. Ciruela, J. Pin, 2010, The Journal of Biological Chemistry.

Dimers and beyond: The functional puzzles of class C GPCRs.

L. Prézeau, J. Pin, J. Kniazeff, 2011, Pharmacology & therapeutics.

A model for the functioning of family 3 GPCRs.

L. Prézeau, J. Bockaert, J. Pin, 2002, Trends in pharmacological sciences.

International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the Recognition and Nomenclature of G Protein-Coupled Receptor Heteromultimers

Michel Bouvier, Lakshmi Devi, Jonathan A. Javitch, 2007, Pharmacological Reviews.

Cell surface detection of membrane protein interaction with homogeneous time-resolved fluorescence resonance energy transfer technology.

Eric Trinquet, Gérard Mathis, J. Pin, 2004, Analytical biochemistry.

Generic GPCR residue numbers - aligning topology maps while minding the gaps.

Chris de Graaf, Stefan Mordalski, Vignir Isberg, 2015, Trends in pharmacological sciences.

Probing the Existence of G Protein-Coupled Receptor Dimers by Positive and Negative Ligand-Dependent Cooperative Binding

Maurice Manning, Christophe Breton, J. Pin, 2006, Molecular Pharmacology.

Building a new conceptual framework for receptor heteromers.

Michel Bouvier, Graeme Milligan, Jonathan A Javitch, 2009, Nature chemical biology.

Asymmetric Functioning of Dimeric Metabotropic Glutamate Receptors Disclosed by Positive Allosteric Modulators*

Francine Acher, L. Prézeau, J. Pin, 2005, Journal of Biological Chemistry.

G Protein–Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives

Martin J. Lohse, Graeme Milligan, Marta Filizola, 2014, Pharmacological Reviews.

Organization and functions of mGlu and GABAB receptor complexes

J. Pin, B. Bettler, Jean-Philippe Pin, 2016, Nature.

Time-resolved FRET strategy to screen GPCR ligand library.

Eric Trinquet, J. Pin, E. Trinquet, 2015, Methods in molecular biology.

Allosteric modulators of group I metabotropic glutamate receptors: novel subtype-selective ligands and therapeutic perspectives.

Fabrizio Gasparini, F. Gasparini, J. Pin, 2002, Current opinion in pharmacology.

Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.

Jianfeng Liu, Xavier Rovira, J. Pin, 2015, Nature chemical biology.

No Ligand Binding in the GB2 Subunit of the GABABReceptor Is Required for Activation and Allosteric Interaction between the Subunits

Gilles Labesse, G. Labesse, J. Pin, 2002, The Journal of Neuroscience.