Jean-Pierre Issa

Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia.

Michael Rytting, Jorge Cortes, Guillermo Garcia-Manero, 2006, Blood.

Ezh2 phosphorylation state determines its capacity to maintain CD8+ T memory precursors for antitumor immunity

Bethany Moore, Shan He, Changhong Li, 2017, Nature Communications.

Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells.

Nita Ahuja, Yi Cai, Yoon-Young Jang, 2012, Cancer cell.

Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells.

Paul Pavlidis, Muneesh Tewari, Zhijun Duan, 2009, Cell stem cell.

Chromosome 5q deletion and epigenetic suppression of the gene encoding α-catenin (CTNNA1) in myeloid cell transformation

Michael F Clarke, C. Bloomfield, A. Look, 2007, Nature Medicine.

Age-related epigenetic changes and the immune system.

J. Issa, Jean-Pierre Issa, 2003, Clinical immunology.

Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation.

Li Mao, Fadlo R Khuri, Diane D. Liu, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Epigenetic variation and cellular Darwinism

J. Issa, Jean-Pierre Issa, 2011, Nature Genetics.

Evolution of decitabine development

Guillermo Garcia-Manero, J. Issa, H. Kantarjian, 2008, Cancer.

A Parallel Phase I/II Clinical Trial Design for Combination Therapies

Xuelin Huang, Donald A Berry, D. Berry, 2007, Biometrics.

Using short‐term response information to facilitate adaptive randomization for survival clinical trials

Jing Ning, Xuelin Huang, Donald A Berry, 2009, Statistics in medicine.