Sharon Shacham

发表

VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux

Michael E. Ragozzino, Frank Lezoualc'h, Paul E. Gold, 2007, Neuropharmacology.

CRM1 Inhibition Sensitizes Drug Resistant Human Myeloma Cells to Topoisomerase II and Proteasome Inhibitors both In Vitro and Ex Vivo

C. Cubitt, D. Sullivan, L. Hazlehurst, 2013, Journal of Cancer.

Modeling the 3D structure of GPCRs: advances and application to drug discovery.

Yael Marantz, O. Becker, Sharon Shacham, 2003, Current opinion in drug discovery & development.

G protein-coupled receptors: in silico drug discovery in 3D.

Shay Bar-Haim, Yael Marantz, Alexander Heifetz, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Understanding XPO1 target networks using systems biology and mathematical modeling.

Asfar S Azmi, A. Azmi, R. Mohammad, 2014, Current pharmaceutical design.

An integrated in silico 3D model-driven discovery of a novel, potent, and selective amidosulfonamide 5-HT1A agonist (PRX-00023) for the treatment of anxiety and depression.

Raphael Nudelman, Yael Marantz, Alexander Heifetz, 2006, Journal of medicinal chemistry.

Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia.

Yuh Min Chook, David Lucas, J. Byrd, 2012, Blood.

Preclinical evaluation of selective inhibitors of nuclear export (SINE) in basal-like breast cancer (BLBC).

Lynda Chin, William Senapedis, L. Chin, 2012 .

Selective inhibitors of nuclear export block pancreatic cancer cell proliferation and reduce tumor growth in mice.

Bin Bao, Asfar S Azmi, B. Bao, 2013, Gastroenterology.

Measurements of the static friction coefficient between bone and muscle tissues.

Amit Gefen, A. Gefen, D. Castel, 2010, Journal of biomechanical engineering.

PREDICT modeling and in‐silico screening for G‐protein coupled receptors

Maya Topf, Shay Bar-Haim, Yael Marantz, 2004, Proteins.

Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia.

Guido Marcucci, Michael Caligiuri, M. Caligiuri, 2012, Blood.

XPO1 (CRM1) Inhibition Represses STAT3 Activation to Drive a Survivin-Dependent Oncogenic Switch in Triple-Negative Breast Cancer

Yan Cheng, M. P. Holloway, R. Altura, 2014, Molecular Cancer Therapeutics.

Genomic and molecular characterization of esophageal squamous cell carcinoma

Li Shang, Xin Xu, Henry Yang, 2014, Nature Genetics.