K Das

Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant.

A. D. Clark, Jianping Ding, R. Pauwels, 1996, Journal of molecular biology.

Touching the heart of HIV-1 drug resistance: the fingers close down on the dNTP at the polymerase active site.

S. Sarafianos, P. Boyer, S. Hughes, 1999, Chemistry & biology.

Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution.

A. D. Clark, Jianping Ding, S. Sarafianos, 1998, Journal of molecular biology.

The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance.

A. D. Clark, Jianping Ding, P. Boyer, 2001, Journal of molecular biology.

Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms.

A. D. Clark, Jianping Ding, E. Arnold, 1996, Structure.

Crystal structure of peanut lectin, a protein with an unusual quaternary structure.

M Vijayan, A. Surolia, M. Vijayan, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Evolution of anti-HIV drug candidates. Part 2: Diaryltriazine (DATA) analogues.

R. Pauwels, E. Arnold, F. Daeyaert, 2001, Bioorganic & medicinal chemistry letters.

Targeting HIV reverse transcriptase for anti-AIDS drug design: structural and biological considerations for chemotherapeutic strategies.

Jianping Ding, P. Boyer, S. Hughes, 1996, Drug design and discovery.

Conformation, protein-carbohydrate interactions and a novel subunit association in the refined structure of peanut lectin-lactose complex.

M Vijayan, A. Surolia, M. Vijayan, 1996, Journal of molecular biology.

Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance.

A. D. Clark, Jianping Ding, S. Hughes, 1998, Journal of molecular biology.