Willem H Ouwehand

发表

Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation

Nilesh J Samani, Panos Deloukas, Jeanette Erdmann, 2014, Epigenetics.

Correction: Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

Christian Gieger, Thomas Meitinger, Andres Metspalu, 2015, Nature Communications.

Blood pressure loci identified with a gene-centric array.

Jean Tichet, Tom R. Gaunt, Jackie A Cooper, 2011, American journal of human genetics.

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Christian Gieger, Thomas Meitinger, Inês Barroso, 2009, Nature Genetics.

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

Henning Gall, Andrea Olschewski, Horst Olschewski, 2018, Nature Communications.

Inheritance of low-frequency regulatory SNPs and a rare null mutation in exon-junction complex subunit RBM8A causes TAR

Ana Cvejic, Panos Deloukas, Matthew E Hurles, 2012, Nature Genetics.

Human phenotype ontology annotation and cluster analysis to unravel genetic defects in 707 cases with unexplained bleeding and platelet disorders

Sylvia Richardson, Augusto Rendon, Sjoert B. G. Jansen, 2015, Genome Medicine.

Chromosome contacts in activated T cells identify autoimmune disease candidate genes

Ellen Schofield, Jonathan Cairns, Peter Fraser, 2017, Genome Biology.

Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome

Nilesh J Samani, Panos Deloukas, Jeanette Erdmann, 2012, The Lancet.

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

Christian Gieger, Uwe Völker, Mario Falchi, 2009, Nature Genetics.

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

Tom R. Gaunt, Fotios Drenos, Meena Kumari, 2012, American journal of human genetics.

Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody.

Richard W Farndale, Ashley Buckle, W. Ouwehand, 2004, Blood.

Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension

Fengyuan Hu, Kevin Rue-Albrecht, Patrick Deegan, 2017, Circulation.

Inherited platelet disorders: toward DNA-based diagnosis.

Ernest Turro, Kathleen Freson, Claire Lentaigne, 2016, Blood.

A genome-wide association study identifies three loci associated with mean platelet volume.

Christian Gieger, Thomas Meitinger, Henry Völzke, 2009, American journal of human genetics.

Germline mutations in the transcription factor IKZF5 cause thrombocytopenia.

Randy J Read, Karyn Megy, Suthesh Sivapalaratnam, 2019, Blood.

Increased DNA methylation variability in type 1 diabetes across three immune effector cell types

Paul Flicek, Nicole Soranzo, Simon Heath, 2016, Nature Communications.

Single-chain antibody fragments derived from a human synthetic phage-display library bind thrombospondin and inhibit sickle cell adhesion.

W. Ouwehand, N. Watkins, J. Scott, 2003, Blood.

Common variants near MC4R are associated with fat mass, weight and risk of obesity

Subhajyoti De, Inês Barroso, Philippe Froguel, 2008, Nature Genetics.

Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource

Matthew Hardy, Nicholas J Wareham, Erik Fung, 2009, Nature Genetics.

A gain-of-function variant in DIAPH1 causes dominant macrothrombocytopenia and hearing loss.

William J. Astle, Sylvia Richardson, Kathleen Stirrups, 2016, Blood.

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

Mark Woodward, Yoav Ben-Shlomo, Johan Sundström, 2012 .

Phenotype description and response to thrombopoietin receptor agonist in DIAPH1-related disorder.

Wendy N Erber, Chantal Thys, Kate Downes, 2018, Blood advances.