Stephen G Sligar

发表

Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties.

Yoshitsugu Shiro, Shin-ichi Adachi, S. Sligar, 2002, Journal of inorganic biochemistry.

Kinetics of dithionite-dependent reduction of cytochrome P450 3A4: heterogeneity of the enzyme caused by its oligomerization.

S. Sligar, J. Halpert, B. Baas, 2005, Biochemistry.

Screening of type I and II drug binding to human cytochrome P450-3A4 in nanodiscs by localized surface plasmon resonance spectroscopy.

George C Schatz, Richard P Van Duyne, R. V. Van Duyne, 2009, Analytical chemistry.

Thermotropic phase transition in soluble nanoscale lipid bilayers.

S. Sligar, I. Denisov, Y. Grinkova, 2005, The journal of physical chemistry. B.

Application of Fragment-Based Drug Discovery to Membrane Proteins: Identification of Ligands of the Integral Membrane Enzyme DsbB

Gregg Siegal, Eiso Ab, G. Siegal, 2015 .

Phospholipid phase transitions in homogeneous nanometer scale bilayer discs

S. Sligar, Stephen G Sligar, Andrew W Shaw, 2004, FEBS letters.

Cooperativity in Cytochrome P450 3A4

S. Sligar, I. Denisov, Y. Grinkova, 2007, Journal of Biological Chemistry.

Nanodiscs in Membrane Biochemistry and Biophysics.

S. Sligar, I. Denisov, Stephen G Sligar, 2017, Chemical reviews.

Molecular dynamics simulations of discoidal bilayers assembled from truncated human lipoproteins.

Klaus Schulten, James C. Phillips, James C Phillips, 2005, Biophysical journal.

Nanodiscs separate chemoreceptor oligomeric states and reveal their signaling properties.

Mingshan Li, S. Sligar, G. L. Hazelbauer, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Transducin Activation by Nanoscale Lipid Bilayers Containing One and Two Rhodopsins*

D. Oprian, S. Sligar, T. H. Bayburt, 2007, Journal of Biological Chemistry.

Dissecting the molecular origins of specific protein-nucleic acid recognition: hydrostatic pressure and molecular dynamics.

Klaus Schulten, Dorina Kosztin, K. Schulten, 2002, Biophysical journal.

Ligand Binding to Cytochrome P450 3A4 in Phospholipid Bilayer Nanodiscs

S. Sligar, Y. Grinkova, W. Atkins, 2007, Journal of Biological Chemistry.

Nonlinear analyte concentration gradients for one-step kinetic analysis employing optical microring resonators.

Ryan C Bailey, S. Sligar, R. Bailey, 2012, Analytical chemistry.

Co-incorporation of heterologously expressed Arabidopsis cytochrome P450 and P450 reductase into soluble nanoscale lipid bilayers.

S. Sligar, M. Schuler, H. Duan, 2004, Archives of biochemistry and biophysics.

Assembly of lipids and proteins into lipoprotein particles.

Klaus Schulten, Peter L. Freddolino, Peter L Freddolino, 2007, The journal of physical chemistry. B.

Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins.

S. Sligar, W. Atkins, A. Nath, 2007, Biochemistry.

Finding a single-molecule solution for membrane proteins.

S. Sligar, Stephen G Sligar, 2003, Biochemical and biophysical research communications.

Biomimetic chemical sensors using nanoelectronic readout of olfactory receptor proteins.

Alan Gelperin, A. Gelperin, Mitchell B. Lerner, 2011, ACS nano.

Functional reconstitution of Beta2-adrenergic receptors utilizing self-assembling Nanodisc technology.

S. Sligar, T. H. Bayburt, Stephen G Sligar, 2006, BioTechniques.

Structural analysis of nanoscale self-assembled discoidal lipid bilayers by solid-state NMR spectroscopy.

Ying Li, C. Rienstra, S. Sligar, 2006, Biophysical journal.

Single-molecule height measurements on microsomal cytochrome P450 in nanometer-scale phospholipid bilayer disks

S. Sligar, T. H. Bayburt, Stephen G Sligar, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment.

S. Sligar, I. Denisov, B. Baas, 2004, Archives of biochemistry and biophysics.

Elliptical structure of phospholipid bilayer nanodiscs encapsulated by scaffold proteins: casting the roles of the lipids and the protein.

Lise Arleth, Robert Feidenhans'l, Kell Mortensen, 2010, Journal of the American Chemical Society.

Modulation of the cytochrome P450 reductase redox potential by the phospholipid bilayer.

A. Das, S. Sligar, Stephen G Sligar, 2009, Biochemistry.

Blood clotting reactions on nanoscale phospholipid bilayers.

James H Morrissey, Emad Tajkhorshid, E. Tajkhorshid, 2008, Thrombosis research.

The Ferrous-Dioxygen Intermediate in Human Cytochrome P450 3A4

S. Sligar, I. Denisov, Y. Grinkova, 2006, Journal of Biological Chemistry.

The Local Phospholipid Environment Modulates the Activation of Blood Clotting*

James H Morrissey, S. Sligar, Stephen G Sligar, 2007, Journal of Biological Chemistry.

Mechanism of drug-drug interactions mediated by human cytochrome P450 CYP3A4 monomer.

Emad Tajkhorshid, Javier L Baylon, E. Tajkhorshid, 2015, Biochemistry.

Interfacing lipid bilayer nanodiscs and silicon photonic sensor arrays for multiplexed protein-lipid and protein-membrane protein interaction screening.

Ryan C Bailey, S. Sligar, R. Bailey, 2013, Analytical chemistry.

Disassembly of nanodiscs with cholate.

Klaus Schulten, Peter L Freddolino, Amy Y Shih, 2007, Nano letters.

Self‐assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers

S. Sligar, T. H. Bayburt, Stephen G Sligar, 2003, Protein science : a publication of the Protein Society.

Membrane protein assembly into Nanodiscs

S. Sligar, T. H. Bayburt, Stephen G Sligar, 2010, FEBS letters.

Nanodiscs for structural and functional studies of membrane proteins

S. Sligar, I. Denisov, Stephen G Sligar, 2016, Nature Structural &Molecular Biology.

Direct solubilization of heterologously expressed membrane proteins by incorporation into nanoscale lipid bilayers.

S. Sligar, M. Schuler, T. H. Bayburt, 2003, BioTechniques.