Mu Yuan

发表

Comparative Molecular Field Analysis (CoMFA) and Comparative Molecular Similarity Indices Analysis (CoMSIA) Studies on α1A-Adrenergic Receptor Antagonists Based on Pharmacophore Molecular Alignment

Xin Zhao, Min-sheng Chen, Biyun Huang, 2011, International journal of molecular sciences.

Design, synthesis and biological evaluation of novel arylpiperazine derivatives on human prostate cancer cell lines.

Biyun Huang, Mu Yuan, Hong Chen, 2015, Bioorganic & medicinal chemistry letters.

Identification of human cytochrome P450 isozymes involved in the metabolism of naftopidil enantiomers in vitro

Mu Yuan, Lijun Zhu, Xia-wen Liu, 2014, The Journal of pharmacy and pharmacology.

Synthesis, crystal structure, biological evaluation, and molecular docking studies of quinoline-arylpiperazine derivative as potent α 1A -adrenoceptor antagonist

R. Jiang, Mu Yuan, W. Xu, 2017 .

Design, synthesis, crystal structure, biological evaluation and molecular docking studies of carbazole-arylpiperazine derivatives.

Wei Xu, R. Jiang, Mu Yuan, 2016, Bioorganic & medicinal chemistry.

Ligand-based pharmacophore model of N-Aryl and N-Heteroaryl piperazine alpha 1A-adrenoceptors antagonists using GALAHAD.

Xin Zhao, Biyun Huang, Hong Ji, 2010, Journal of molecular graphics & modelling.

Novel naftopidil derivatives containing methyl phenylacetate and their blocking effects on α1D/1A-adrenoreceptor subtypes.

Mu Yuan, Xia-wen Liu, Junjun Huang, 2018, Bioorganic & medicinal chemistry letters.

Synthesis, biological evaluation and SAR of naftopidil-based arylpiperazine derivatives.

Mu Yuan, Hong Chen, Jiangxiu Niu, 2018, Bioorganic & medicinal chemistry letters.

Synthesis and Cytotoxic Activity Evaluation of Novel Arylpiperazine Derivatives on Human Prostate Cancer Cell Lines

Biyun Huang, Mu Yuan, Fang Xu, 2014, Molecules.

Synthesis, structure-activity relationship and biological evaluation of novel arylpiperzines as α1A/1D-AR subselective antagonists for BPH.

Bing Li, J. Xu, Xianqiang Sun, 2015, Bioorganic & medicinal chemistry.

X-ray Crystallography, DFT Calculations and Molecular Docking of Indole-Arylpiperazine Derivatives as α1A-Adrenoceptor Antagonists

B. Shao, W. Xu, R. Jiang, 2015, Molecules.

Crystal structures, absolute configurations and molecular docking studies of naftopidil enantiomers as α1D-adrenoceptor antagonists

W. Xu, R. Jiang, Mu Yuan, 2017, Acta pharmaceutica Sinica. B.

Chemical Constituents Having Antioxidant Activities of Solanum lyratum

Hong Ji, Mu Yuan, Langhuan Hou, 2014, Chemistry of Natural Compounds.

Pharmacokinetics, tissue distribution and relative bioavailability of puerarin solid lipid nanoparticles following oral administration.

Shi-Ming Liu, Cheng-Feng Luo, Shi-ming Liu, 2011, International journal of pharmaceutics.

UDP-glucuronosyltransferase 1A1 is the principal enzyme responsible for puerarin metabolism in human liver microsomes

Shi-ming Liu, N. Hou, Min-sheng Chen, 2012, Archives of Toxicology.

Synthesis and biological evaluation of arylpiperazine derivatives as potential anti-prostate cancer agents.

Mu Yuan, Shanchao Zhao, Hong Chen, 2019, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of estrone 3-O-ether derivatives containing the piperazine moiety

Mu Yuan, Hong Chen, Xue Liang, 2018, Steroids.

A Novel Rearrangement of Talatisamine Derivatives

Hong Ji, Mu Yuan, 2012 .

Synthesis of α-Alkyltetronic Acids

Biyun Huang, Hong Ji, Mu Yuan, 2012 .

Synthesis and Antitumor Activity of Novel Arylpiperazine Derivatives Containing the Saccharin Moiety

Mu Yuan, Hong Chen, Bingbing Xu, 2017, Molecules.

Metabolic profile of puerarin in rats after intragastric administration of puerarin solid lipid nanoparticles

Shi-ming Liu, N. Hou, Min-sheng Chen, 2013, International journal of nanomedicine.

Determination of puerarin in rat plasma by rapid resolution liquid chromatography tandem mass spectrometry in positive ionization mode.

Shi-ming Liu, Min-sheng Chen, Biyun Huang, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Metabolites of puerarin identified by liquid chromatography tandem mass spectrometry: similar metabolic profiles in liver and intestine of rats.

Shi-ming Liu, Min-sheng Chen, Hong Ji, 2010, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Puerarin-7-O-glucuronide, a water-soluble puerarin metabolite, prevents angiotensin II-induced cardiomyocyte hypertrophy by reducing oxidative stress

Shi-ming Liu, N. Hou, Min-sheng Chen, 2017, Naunyn-Schmiedeberg's Archives of Pharmacology.

Novel naftopidil-related derivatives and their biological effects as alpha1-adrenoceptors antagonists and antiproliferative agents.

Mu Yuan, Xia-wen Liu, Liu Zhu, 2015, European journal of medicinal chemistry.

Pharmaceutical evaluation of naftopidil enantiomers: Rat functional assays in vitro and estrogen/androgen induced rat benign prostatic hyperplasia model in vivo.

Biyun Huang, Mu Yuan, Yi Cai, 2016, European journal of pharmacology.

Poor and enantioselective bioavailability of naftopidil enantiomers is due to extensive and stereoselective metabolism in rat liver

Y. Cai, Biyun Huang, Mu Yuan, 2017, Journal of pharmaceutical and biomedical analysis.

Chemical Constituents Having Antioxidant Activities of Solanum lyratum

Hong Ji, Mu Yuan, Langhuan Hou, 2014, Chemistry of Natural Compounds.

Legionella qingyii sp. nov., isolated from water samples in China.

Xiao-Yong Zhan, Mu Yuan, Hai-yan Wu, 2019, International journal of systematic and evolutionary microbiology.

Identification of Two Novel α1-AR Agonists Using a High-Throughput Screening Model

Hong Chen, Biyun Huang, Mu Yuan, 2014, Molecules.

Antioxidant constituents from leaves of Engelhardtia roxburghiana

Hong Ji, Mu Yuan, Zhuoting Zhou, 2012, Chemistry of Natural Compounds.

Enantiospecific determination of naftopidil by RRLC-MS/MS reveals stereoselective pharmacokinetics and tissue distributions in rats.

Biyun Huang, Mu Yuan, Y. Rong, 2015, Journal of Pharmaceutical and Biomedical Analysis.

Simultaneous stereoselective analysis of naftopidil and O-desmethyl naftopidil enantiomers in rat feces using an online column-switching high-performance liquid chromatography method.

Mu Yuan, Lijun Zhu, Xia-wen Liu, 2014, Biomedical chromatography : BMC.

Determination of naftopidil enantiomers in rat plasma using chiral solid phases and pre-column derivatization high-performance liquid chromatography.

Mu Yuan, Yinxiang Sun, Xia-wen Liu, 2012, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Design, synthesis and biological evaluation of novel arylpiperazine derivatives on human prostate cancer cell lines

Mu Yuan, Hong Chen, Bingbing Xu, 2016 .