J. Marquette

发表

The 2.4-Å crystal structure of the penicillin-resistant penicillin-binding protein PBP5fm from Enterococcus faecium in complex with benzylpenicillin

E. Sauvage, G. Leonard, P. Charlier, 2002, Cellular and Molecular Life Sciences CMLS.

Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.

E. Mandine, G. Lange, P. Broto, 2003, Journal of medicinal chemistry.

SAR and X-ray. A new approach combining fragment-based screening and rational drug design: application to the discovery of nanomolar inhibitors of Src SH2.

Jean-Pierre Marquette, E. Mandine, G. Lange, 2002, Journal of medicinal chemistry.

Factors Predicting Likelihood of Eating Irradiated Meat

D. Reddy, R. Fleming, O. Crowley, 2013 .

KRAS G12C fragment screening renders new binding pockets

M. Mathieu, L. Debussche, M. Lowinski, 2021, Small GTPases.

Discovery of thioazepinone ligands for Src SH2: from non-specific to specific binding.

T. T. Duc, E. Mandine, G. Lange, 2001, Bioorganic & medicinal chemistry letters.

Morphologic and immunologic characterization of human basophils developed in cultures of cord blood mononuclear cells.

D. Conrad, A. Dvorak, J. Marquette, 1985, Journal of immunology.

Discovery of thioazepinone ligands for Src SH2: from non-specific to specific binding.

T. T. Duc, E. Mandine, G. Lange, 2001, Bioorganic & medicinal chemistry letters.

Discovery and optimization of new benzimidazole- and benzoxazole-pyrimidone selective PI3Kβ inhibitors for the treatment of phosphatase and TENsin homologue (PTEN)-deficient cancers.

J. Nicolas, C. Lengauer, L. Vincent, 2012, Journal of medicinal chemistry.

Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule

Dietmar Hoffmann, Jean-Pierre Marquette, Magali Mathieu, 2014, The Journal of Biological Chemistry.

Discovery and optimization of pyrimidone indoline amide PI3Kβ inhibitors for the treatment of phosphatase and tensin homologue (PTEN)-deficient cancers.

Jean-Pierre Marquette, Magali Mathieu, Thomas Bertrand, 2014, Journal of medicinal chemistry.

A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy.

Jean-Pierre Marquette, Magali Mathieu, Thomas Bertrand, 2014, Nature chemical biology.

Automated harvesting and processing of protein crystals through laser photoablation

Peter Murphy, Gergely Papp, Florent Cipriani, 2016, Acta crystallographica. Section D, Structural biology.

Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator‐Activated Receptor (PPAR) γ/δ Agonists with High Potency and in vivo Efficacy

H. Matter, M. Mathieu, S. Keil, 2011, ChemMedChem.

Structures of a pan‐specific antagonist antibody complexed to different isoforms of TGFβ reveal structural plasticity of antibody–antigen interactions

M. Mathieu, Huawei Qiu, R. Wei, 2014, Protein science : a publication of the Protein Society.

Discovery of (2S)-8-[(3R)-3-methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2H-pyrimido[1,2-a]pyrimidin-6-one: a novel potent and selective inhibitor of Vps34 for the treatment of solid tumors.

M. Mathieu, C. García-echeverría, F. Gay, 2014, Journal of medicinal chemistry.

A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy.

M. Mathieu, C. García-echeverría, B. Pasquier, 2014, Nature chemical biology.

Structures of a pan‐specific antagonist antibody complexed to different isoforms of TGFβ reveal structural plasticity of antibody–antigen interactions

M. Mathieu, Huawei Qiu, R. Wei, 2014, Protein science : a publication of the Protein Society.