A. Zervosen

发表

Structural and mechanistic basis of penicillin-binding protein inhibition by lactivicins

A. Luxen, B. Joris, T. Brown, 2007, Nature Chemical Biology.

New Noncovalent Inhibitors of Penicillin-Binding Proteins from Penicillin-Resistant Bacteria

A. Luxen, S. Turk, B. Joris, 2011, PloS one.

Structure guided development of potent reversibly binding penicillin binding protein inhibitors.

A. Luxen, C. Fishwick, E. Sauvage, 2011, ACS medicinal chemistry letters.

Application of recombinant sucrose synthase-large scale synthesis of ADP-glucose

L. Elling, U. Römer, A. Zervosen, 1998 .

Fully automated radiosynthesis of N(1)-[(18)F]fluoroethyl-tryptophan and study of its biological activity as a new potential substrate for indoleamine 2,3-dioxygenase PET imaging.

A. Luxen, C. Lemaire, A. Plenevaux, 2016, Nuclear medicine and biology.

Enantioselective synthesis of α-benzylated lanthionines and related tripeptides for biological incorporation into E. coli peptidoglycan.

A. Luxen, C. Lemaire, B. Joris, 2014, Organic & biomolecular chemistry.

N (1)-Fluoroalkyltryptophan Analogues: Synthesis and in vitro Study as Potential Substrates for Indoleamine 2,3-Dioxygenase.

A. Luxen, C. Lemaire, A. Plenevaux, 2015, ACS medicinal chemistry letters.

Unprecedented inhibition of resistant penicillin binding proteins by bis-2-oxoazetidinyl macrocycles

G. Dive, E. Sauvage, J. Marchand-Brynaert, 2012 .

Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors.

A. Luxen, C. Schofield, D. Fischer, 2009, Journal of medicinal chemistry.

Small molecule inhibitors of peptidoglycan synthesis targeting the lipid II precursor.

J. Frère, S. Turk, T. Vernet, 2011, Biochemical pharmacology.

Aminophosphonic Acids and Aminobis(phosphonic acids) as Potential Inhibitors of Penicillin-Binding Proteins

J. Marchand-Brynaert, P. Lassaux, A. Zervosen, 2008 .

Inhibition of Streptococcus pneumoniae Penicillin-Binding Protein 2x and Actinomadura R39 DD-Peptidase Activities by Ceftaroline

J. Frère, A. Zapun, A. Zervosen, 2012, Antimicrobial Agents and Chemotherapy.

Interactions between Penicillin-Binding Proteins (PBPs) and Two Novel Classes of PBP Inhibitors, Arylalkylidene Rhodanines and Arylalkylidene Iminothiazolidin-4-ones

J. Frère, W. Lu, A. Zervosen, 2004, Antimicrobial Agents and Chemotherapy.

Characterization of the proteins encoded by the Bacillus subtilis yoxA-dacC operon.

A. Luxen, J. Frère, C. Duez, 2009, FEMS microbiology letters.

Stereoselective synthesis of lanthionine derivatives in aqueous solution and their incorporation into the peptidoglycan of Escherichia coli.

A. Luxen, C. Lemaire, B. Joris, 2014, Bioorganic & Medicinal Chemistry.

UDP-N-Acetyl-α-D-glucosamine as acceptor substrate of β-1,4-galactosyltransferase. Enzymatic synthesis of UDP-N-acetyllactosamine

E. Berger, R. Gutiérrez Gallego, J. Kamerling, 1999, Glycoconjugate Journal.

Synthesis of Nucleotide-Activated Oligosaccharides by ?-Galactosidase from Bacillus circulans

J. Kamerling, J. Vliegenthart, L. Elling, 2001, Biological chemistry.

Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin-binding protein.

A. Luxen, J. Frère, B. Joris, 2011, Journal of the American Chemical Society.

Synthesis of protected α-alkyl lanthionine derivatives

A. Luxen, C. Lemaire, A. Plenevaux, 2014 .

Development of solid-supported methodology for the preparation of peptidoglycan fragments containing (2S,6R)-diaminopimelic acid

A. Luxen, C. Lemaire, B. Joris, 2016 .

Synthesis and Evaluation of 3-( Dihydroxyboryl ) benzoic Acids as D , D-Carboxypeptidase R 39 Inhibitors

C. Schofield, D. Fischer, A. Zervosen, 2009 .

Development of New Drugs for an Old Target — The Penicillin Binding Proteins

A. Luxen, J. Frère, E. Sauvage, 2012, Molecules.

Synthesis and biological evaluation of potential threonine synthase inhibitors: Rhizocticin A and Plumbemycin A.

A. Luxen, B. Joris, C. Damblon, 2013, Bioorganic & medicinal chemistry.

One-pot enzymatic synthesis of the Galα1→3Galβ1→4GlcNAc sequence within situ UDP-Gal regeneration

Lothar Elling, Cornelis H. Hokke, L. Elling, 1996, Glycoconjugate Journal.

A NOVEL THREE-ENZYME REACTION CYCLE FOR THE SYNTHESIS OF N-ACETYLLACTOSAMINE WITH IN SITU REGENERATION OF URIDINE 5'-DIPHOSPHATE GLUCOSE AND URIDINE 5 '-DIPHOSPHATE GALACTOSE

Lothar Elling, L. Elling, A. Zervosen, 1996 .

Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening.

André Luxen, Laurence Miguet, Aline Thomas, 2009, Journal of medicinal chemistry.

Structural basis of the inhibition of class A beta-lactamases and penicillin-binding proteins by 6-beta-iodopenicillanate.

A. Luxen, G. Dive, B. Joris, 2009, Journal of the American Chemical Society.

Specific structural features of the N-acetylmuramoyl-L-alanine amidase AmiD from Escherichia coli and mechanistic implications for enzymes of this family.

A. Luxen, J. Frère, B. Joris, 2010, Journal of molecular biology.

1,6-AnhMurNAc derivatives for assay development of amidase AmiD.

A. Luxen, J. Frère, B. Joris, 2010, Bioorganic & medicinal chemistry.

Synthesis and evaluation of boronic acids as inhibitors of Penicillin Binding Proteins of classes A, B and C.

A. Luxen, B. Joris, E. Sauvage, 2012, Bioorganic & medicinal chemistry.

Structure-guided design of cell wall biosynthesis inhibitors that overcome β-lactam resistance in Staphylococcus aureus (MRSA).

A. Luxen, B. Joris, C. Schofield, 2011, ACS chemical biology.

Inactivation of Aeromonas hydrophila metallo-beta-lactamase by cephamycins and moxalactam.

J. Frère, J. V. Van Beeumen, B. Devreese, 2001, European journal of biochemistry.

Combined enzymatic synthesis of nucleotide (deoxy) sugars from sucrose and nucleoside monophosphates

L. Elling, A. Zervosen, Andreas Stein, 1996 .

Application of Sucrose Synthase in the Synthesis of Nucleotide Sugars and Saccharides

L. Elling, A. Zervosen, 1999 .

Continuous Enzymatic Synthesis of 2′-Deoxythymidine-5′-(α-D-glucopyranosyl)diphosphate†

M. Kula, L. Elling, A. Zervosen, 1994 .

Isolation of sucrose synthase from rice (Oryza sativa) grains in pilot scale for application in carbohydrate synthesis

M. Kula, L. Elling, A. Zervosen, 1995 .

Small molecule inhibitors of peptidoglycan synthesis targeting the lipid II precursor.

J. Frère, S. Turk, T. Vernet, 2011, Biochemical pharmacology.

Specific structural features of the N-acetylmuramoyl-L-alanine amidase AmiD from Escherichia coli and mechanistic implications for enzymes of this family.

A. Luxen, J. Frère, B. Joris, 2010, Journal of molecular biology.